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Popular Abstract in Swedish Man har tidigare sett att patienter med akut myeloisk leukemi (AML) har förhöjda nivåer av det cellcykelreglerande proteinet cyklin A1 och överuttryck av cyklin A1 i de myeloiska cellerna hos transgena möss resulterade i att mössen utvecklade AML. Syftet med avhandlingen var att ytterligare studera uttrycket och regleringen av cyklin A1 i hematopoetiska celler. Vi börja
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Transplants of fetal ventral mesencephalic tissue are known to contain a mixture of two major dopamine (DA) neuron types: the A9 neurons of the substantia nigra pars compacta (SNpc) and the A10 neurons of the ventral tegmental area (VTA). Previous studies have suggested that these two DA neuron types may differ in their growth characteristics, but, because of technical limitations, it has so far b
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The advent of safe languages like Java on the real-time systems scene motivates further research on efficient strategies for non-intrusive garbage collection and especially GC scheduling. This thesis presents new approaches to flexible and robust memory management from an engineering perspective and is a step towards write once --- run anywhere with hard real-time performance. The traditional app
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Popular Abstract in Swedish Vad säger notbilden? Notation är av central betydelse i västerländsk tonal musik. Repertoarens utsträckning över flera århundraden gör det angeläget att studera hur musikaliskt innehåll medieras genom notation. I denna studie har strategiskt utvalda musikers sätt att ta sig an noterna till tonal musik undersökts. Slutsatser har dragits beträffande notbildens funktionerAbstract Centering on notation is a characteristic of Western tonal music. The printed scores are expected to provide the necessary information on musical expression. In this study, strategically selected contemporary musicians’ ways of under-standing the printed scores are investigated. All participants are thoroughly familiar with musical practice in Western tonal tradition. The intention is to
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INTRODUCTION: General practitioners are often interested in doing research but are hampered by lack of time and research training. Interpreting the results of others can also be difficult. For this reason a course in basic research methods for GPs was started in Sweden in 1989. It was originally aimed at GPs but was later extended to hospital physicians as well. The course is given regionally and
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Semenogelins I and II (SgI and SgII) are homologous and rapidly evolving proteins that have a repetitive primary structure and are synthesized mainly in the seminal vesicles. Upon ejaculation, a gelatinous coagulum is formed when the semenogelin-rich secretion from the seminal vesicles is mixed with the prostate secretion, which contains high concentrations of zinc(II) and proteases. These proteas
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It was recently shown that prostacyclin at a low dose reduces cortical cell death following brain trauma in the rat. Conceivably, prostacyclin with its vasodilatory, anti-aggregatory, anti-adhesive and permeability-reducing properties improved a compromised perfusion caused by post-traumatic vasoconstriction, microthrombosis and increased microvascular permeability. The objective of the present st
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OBJECTIVE: Bone morphogenetic protein-2 (BMP2) plays a critical role in osteoblastogenesis and adipogenesis from osteoprogenitor cells. The balance between osteogenic and adipogenic effects is influenced by BMP2 concentration, transcription factors and age. BMP2 single nucleotide polymorphisms (SNPs) may contribute to osteoporosis risk, but the relationship between adiposity and body composition h
