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The fibrinolytic activity of plasmin plays a fundamental role in resolution of blood clots and clearance of extravascular deposited fibrin in damaged tissues. These vital functions of plasmin are exploited by malignant cells to accelerate tumor growth and facilitate metastases. Mice lacking functional plasmin thus display decreased tumor growth in a variety of cancer models. Interestingly, this ro
Background: In spite of considerable rice production gains over the past 50 years, Sub-Saharan Africa is becoming increasingly dependent on rice imports as demand is outpacing domestic supply. The serious economic and social strains caused by this have urged national leaders to address production deficits. The aim of this article is to analyse and discuss the drivers behind recent changes in rice
The Lyme disease spirochetes, Borrelia burgdorferi sensu stricto, Borrelia afzelii and Borrelia garinii. are tick-borne pathogens that can cause chronic disseminated infections. To survive in the human host borreliae need to evade the immune system. It is already well known that B. burgdorferi ss. and B. afzelii bind the complement (C) alternative pathway inhibitor factor H from serum using OspE a
Microscale acoustofluidics utilizes ultrasound to manipulate microparticles flowing through a microchannel. Using this technique, particles or cells can be e.g. separated, aligned, washed or trapped. It is however an emerging technology that should be further developed in order to maximally capitalize on its potential. One possible improvement is to increase the particle migration velocity by incr
På senare tid har en särskild typ av företag, vars affärsverksamhet går ut på att hyra bostadslägenheter för att vidareupplåta dem till företag som behöver personalbostäder, vuxit fram på hyresmarknaden i Sverige. Detta fenomen är vanligast i storstadsregionerna, företagen brukar kallas för mellanhandsföretag och bostäderna som hyrs ut för företagsbostäder. En av reglerna som aktualiseras vid dennIn recent years, a new category of business has emerged within the Swedish rental housing market, operating by leasing residential flats and subsequently subletting them to companies in need of staff accommodation. This phenomenon is most prevalent in metropolitan areas. Such businesses are usually referred to as intermediary companies, and the flats as corporate apartments. One of the legal provi
I juli 2023 tillsatte regeringen en utredning i syfte att genomföra en övergri- pande översyn av straffskalorna samt lägga fram förslag till ett reformerat och mer rättvist påföljdssystem. Regeringen framhåller i direktivet att straffsyste- met bör uttrycka en tydligare klandervärdering av brottsliga gärningar för att undvika att brottsoffer upplever rättsprocessen som ytterligare en kränkning. DeIn July 2023, the Swedish government appointed an inquiry with the purpose of conducting a comprehensive review of the penalty scales and presenting proposals for a reformed and fairer penalty system. The government empha- sizes in the directive that the penal system should express a clearer condem- nation of the blameworthiness of criminal acts in order to avoid that victims experience the legal
Låneförbuden i den svenska aktiebolagslagen (ABL) utgör kapitalskydds-regler och innefattar två separata förbudsbestämmelser. Först, ett generellt låneförbud, ofta benämnt som förbudet mot närståendelån, som specificeras i 21 kap. 1§ ABL. Detta förbud hindrar aktiebolag från att låna ut pengar till exempelvis styrelsemedlemmar, aktieägare i bolaget, eller andra bolag inom samma koncern. För det anThe loan prohibitions in the Swedish Aktiebolagslagen (ABL) constitute capital protection rules and mainly encompass two separate prohibition provisions. First, a general loan prohibition, often referred to as the prohibi-tion against loans to related parties (närståendelåneförbudet), which is specified in ABL chapter 21, section 1. This prohibition prevents Swedish limited companies (Sw. aktiebol
The purpose of this thesis is to improve the understanding of how generative AI contributes to change the conditions for teens’ everyday information search, as well as to highlight how user and ChatGPT interact within information search. To achieve this, qualitative interviews with teens between the ages of 15 and 19 were conducted. In addition, prompts written by the teens to ChatGPT were collect
Stroke is a highly debilitating disease of the central nervous system occurring as a result of cerebral ischemia – deprivation of a cerebral tissue from blood that supplies it with oxygen and glucose, causing the cells in affected tissue to die, bringing about a large number of downstream effects and responses. Localized infarction in the brain also triggers tissue death and related responses in r
Offentlig-privat samverkan (”OPS”) kan ses som en typ av offentlig upphandling där en eller flera privata aktörer, genom ett gemensamt projektbolag, levererar en tjänst på uppdrag av en offentlig beställare, vanligtvis ett infrastrukturprojekt inom transport, energiförsörjning, utbildning eller sjukvård. Utmärkande för OPS är att projektbolaget ansvarar för alla delar av projektet, inklusive projePublic-private partnership ("PPP") can be seen as a type of public procurement where one or more private actors, through a joint project company, deliver a service on behalf of a public client, typically an infrastructure project in transportation, energy supply, education, or healthcare. A distinguishing feature of PPP is that the project company is responsible for all aspects of the pr
Den sociala indikationen är ett juridikens medel för att i vissa fall rättfärdiga att vuxna missbrukare bereds vård, oberoende deras eget tycke. Ett sådant tvångsförfarande innebär i grunden en inskränkning av mänskliga fri- och rättigheter. I ljuset av denna inskränkning är det alldeles nödvändigt att det legitima tvångsförfarandet föregås dels av en tydlig och precis rättsreglering, dels av en fThe social indication is a legal mechanism that, in certain cases, serves to justify compulsory care for adult substance abusers, irrespective of their con-sent. Such a coercive measure inherently entails a restriction of human rights and freedoms. In light of this restriction, it is essential that the legitimate compulsory measure be preceded by a clear and precise legal regulation, as well as a
Since 2010 the first, second, third and fourth Swedish public pension funds (AP-funds)have drastically increased their exposure towards real estate. The AP-funds have done this through starting and acquiring private property companies. With these companies,the funds have gradually increased their real estate assets. This study aims to identify the four AP-funds investment strategies in real estate
The labor market for IT-oriented professions, especially software engineers, is characterized by extensive skills gaps due to fast-evolving technology. The purpose of this thesis is to shed light on the work toward closing the skills gap in IT-oriented professions, especially for software engineers, by providing suggestions on how the workforce can be prepared with the skills needed for tomorrow -
This thesis explores two interrelated issues when it comes to traditional alcohol in Tanzania and its day-to-day activities: identity formation and local economic life. Given the fact that drinking traditional alcohol in Africa is an intrinsic part of social life, it becomes an object in the articulation of diversity, coexistence, and preservation of identity. The study presents women as nodes thr
