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Biological and molecular evidence for existence of lymphoid-primed multipotent progenitors
Studies from our and other laboratories have over the last 2 years implicated the existence of multipotent progenitors (MPPs) with combined granulocyte-macrophage, B cell, and T cell potential, but little or no megakaryocyte-erythroid (MkE) potential in the adult bone marrow Lineage (-)SCA-1 +KIT+ (LSK) compartment of multipotent stem and progenitor cells. The evidence for the existence of LSKCD34
Phototoxicity
Phototoxicity occurs when a substance is toxic only under the action of light, and can, depending on the mechanism of toxic action, be divided into type I and type II phototoxicity. Other types are sometimes recongnized, and sometimes toxicity occurs through more than one mechanism. Plants often use phototoxins for their defense. They may be harmful to man, but also exploited for medical treatment
High-Resolution Measurement of the 4He(g,n) Reaction in the Giant Resonance Region
Popular Abstract in Swedish Kärnan kan ses som en samling nukleoner vilka hålls samman av den starka kraften. Nukleonerna är protoner (p) med laddning +1 och neutroner (n) med laddning 0. Kraften kan beskrivas som ett utbyte av mesoner såsom pioner (pi) vilka förekommer i tre laddningstillstånd pi+, pi- och pi0 (laddning +1, -1 och 0). Inuti kärnan rör sig nukleonerna och utbytesmesonerna vilket g
Meta-managing: A Study on How Superiors and Subordinates Manage Their Relationship in Everyday Work
In virtually every organization we find formally appointed managers, but nevertheless we tend to condemn the idea of formal hierarchy and celebrate alternative modes of governance that better respect the discretion of employees. This tension, that seemingly surrounds the vertical dimension of contemporary organizations, forms the backdrop of this study which examines how superiors and subordinates
Detection of HCl in a Premixed CH4/O-2/Ar Flame Seeded with CHCl3 Using Mid-IR Polarization Spectroscopy
Medical Laser-Induced Thermotherapy - Models and Applications
Contact allergens in p-tert-butylphenol-formaldehyde resin
Popular Abstract in Swedish p-tert-Butylfenol-formaldehydharts (PTBP-F-R) är ett bindemedel som används i vissa limmer och målarfärger. Det har använts sedan 1950-talet och redan från denna tid finns rapporter om allergier. PTBP-F-R ingår i den internationella standardserien av kontaktallergen. Råvaror för framställning av hartset är p-tert-butylfenol och formaldehyd. Det färdiga hartset består av
Effect of Pin Base-Fillet on Heat Transfer Enhancement of an Internal Blade Pin-Finned Tip-Wall
Gene expression in the dorsal root ganglion and the role of PAI-1 and amphiregulin during regeneration
This thesis is concerned with two aspects of peripheral nerve injury. First the early changes in the gene expression of the dorsal root ganglion (DRG) in response to sciatic nerve injury as revealed by micro-array analysis. Second an examination of the effect of PAI-1 and amphiregulin on survival and axonal outgrowth from DRG. Based on the micro-array analysis, performed on DRG 12 h and 24 h post
Protein Surfaces Probed by Aqueous Two-phase Partitioning
This thesis is concerned primarily with peptide and protein partitioning in aqueous two-phase systems and the connection between partitioning behavior and protein structure. The surface properties of a protein is often crucial for recognition and interaction with other molecules. Important functional residues can be identified by mutational analysis. There is a need for rapid methods to study prot
Glacial history of Northeast Greenland: cosmogenic nuclide constraints on chronology and ice dynamics
Popular Abstract in Swedish Senpleistocen nedisningshistoria på Nordöstgrönland: kosmogen exponeringsdatering, isutbredning och isdynamik Under den senaste istiden var periodvis stora delar av landmassorna på norra halvklotet istäckta. Idag är den Grönländska inlandsisen den enda större återstoden av detta, men likväl binder den tillsammans med isen i Antarktis och jordens mindre glaciärer väldigt
Endothelial and cardiac effects of 5-fluorouracil. An experimental and clinical study.
Popular Abstract in Swedish Bakgrund 5-Fluorouracil (5-FU) är ett cytostatikum, även kallat cellgift (ett ämne som hämmar tillväxten av cancerceller), som använts för behandling av cancersjukdom sedan många decennier. Det kan ges både i snabb injektion och i dropp över flera dygn. 5-FU har tyvärr flera vanliga biverkningar. Man kan få påverkan av slemhinnor i magtarm-kanalen, vilket ger sår i munn
Microcalorimetric methods for direct measurement of solubility and solvent activity
New calorimetric methods for direct measurement of solubility and solvent activity are presented. The classical role of calorimetry for measurements of enthalpic parameters is abandoned and the technique is instead used for assessing thermodynamic quantities related to the chemical potential of a substance in a solution. Isothermal calorimetry is here employed as a general analytical method where
Lean burn versus stoichiometric operation with EGR and 3-way catalyst of an engine fueled with natural gas and hydrogen enriched natural gas
Engine tests have been performed on a 9.6 liter spark-ignited engine fueled by natural gas and a mixture of 25/75 hydrogen/natural gas by volume. The scope of the work was to test two strategies for low emissions of harmful gases; lean burn operation and stoichiometric operation with EGR and a three-way catalyst. Most gas engines today, used in city buses, utilize the lean burn approach to achieve
Developing Sustainable Capacity for Disaster Risk Reduction in Southern Africa
Southern Africa suffers from an acute lack in skilled capacities for disaster risk reduction and climate change adaptation. The region, with its unique disaster risk profile, is mostly bound by its inability to effect change and transformation for sustainable development and resilience building. Reasons for these limitations are largely due to the lack of capacities in disaster risk reduction with
Involvement of Eicosanoid Signaling in Intestinal Epithelial Cell Survival
Popular Abstract in Swedish Vad bestämmer om en cell skall dö? En viktig, avgörande faktor är vilken signal cellen får från omgivningen. Den måste nämligen vara mycket öppen för intryck och beredd att tjänstvilligt dö på begäran, eftersom hela den flercelliga varelsen beror av att det fungerar så. Det måste förstås också finnas signaler utifrån som talar om att det är dags att kämpa, att överleva
Field study of the penetration of chlorides and other ions into a high quality concrete marine bridge column
Predictions of Enhanced Heat Transfer of an Internal Blade Tip-Wall with Hemishperical Dimples or Protrusions
The blade tip region encounters high thermal loads because of the hot gas leakage flows, and it must therefore be cooled to ensure a long durability and safe operation. A common way to cool a blade tip is to design serpentine passages with 180-deg turn under the blade tip-cap inside the turbine blade. Improved internal convective cooling is therefore required to increase the blade tip lifetime. Di
DNA Compaction at Surfaces
Popular Abstract in Swedish DNA kan ses som en negativ laddad polymer som samtidigt har grupper som vill undvika vatten och därför bildas den karakteristiska dubbelspiralen. DNA och ett ytaktiv ämne (tensid) som är positivt laddad, bildar olika komplex. Dessa komplex är mycket mer kompakta än DNA själv. I denna avhandling har vi undersökt DNA och DNA-tensid komplex på olika ytor. Vi har använt oli
