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Polymorphism and transcription of Mhc class I genes in a passerine bird, the great reed warbler

The class I genes of the major histocompatibility complex (Mhc) are here investigated for the first time in a passerine bird. The great reed warbler is a rare species in Sweden with a few semi-isolated populations. Yet, we found extensive Mhc class I variation in the study population. The variable exon 3, corresponding to the alpha(2) domain, was amplified from genomic DNA with degenerated primers

Ultrafast formation of a carotenoid radical in LH2 antenna complexes of purple bacteria

The SI-mediated carotenoid to BChl a energy-transfer pathway and carotenoid radical formation have been studied using femtosecond time-resolved transient absorption spectroscopy. A series of LH2 complexes (LH2 = light-harvesting complex 2) from Rhodobacter sphaeroides incorporating carotenoids neurosporene, spheroidene, and spheroidenone were used to explore the effect of conjugation length. The S

Inhibitors in the Swedish population with severe haemophilia A and B : A 20-year survey

Aim: To survey the entire population (n = 116) afflicted with severe haemophilia A or B born in Sweden over a 20-y period (1980-1999), and to examine the epidemiological, genetic and clinical aspects of development of inhibitors to factors VIII and IX (FVIII/FIX). Methods: One hundred of the subjects had haemophilia A and 16 had haemophilia B. All of these subjects had received prophylactic treatm

Streptococcus pyogenes secreted enzymes interacting with the human host

Streptococcus pyogenes is one of the most common bacteria infecting humans. One of the factors contributing to the disease-causing properties is the secreted streptococcal cysteine proteinase, SpeB, which degrades several host proteins in connective tissue and circulation. SpeB activity depends on the transformation from an inactive precursor, zymogen, into a mature proteinase. We show that

Stress-related peptides in suicide attempters

Popular Abstract in Swedish Det är välkänt att patienter som har gjort ett suicidförsök löper en ökad risk att i framtiden ta sitt liv. I de flesta fall görs suicidförsök av individer som på något sätt är utsatta för stress. Stress kan orsakas av en psykisk eller fysisk sjukdom. Psykosociala faktorer, såsom en skilsmässa eller en annan ohållbar situation i hemmet eller på arbetet, kan också förors

Modelling the gold market, explaining the past and assessing the physical and economical sustainability of future scenarios

By using an integrated dynamic model we are able to reconstruct the supply and gold price of the past (1920-2010) and this is used to predict the future supply of gold to the market and to make a forecast of the goldprice 2010-2100. The model was validated against field data for the period 1920-2010 and it performs well. The model GOLD is implemented in the STELLA® software and the model described

Driving Forces of Supplier Integration - A Case Study from the Grocery Industry

The focal company in this study is establishing a partnership style of’ relationships with a few selected suppliers. The article focuses on the driving forces behind such an initiative. It attempts to answer the questions why this company is trying to develop a closer working relationship with one of the selected suppliers, the supplier of corrugated board. The purpose of the article is thus to an

A World of Tropes?

Abstract in UndeterminedWhy should one hold that the world is a world of tropes? Or, more generally: How do we justify our ontological conclusions? It seems clear that the only evidence at our disposal must belong to appearances. For a realist, however, it is unreasonable to think that our conceptualisation of reality will reveal to us reality as it is independently of how it seems. You simply can

From Sequence to Structure- Characterizing Human and Plant Aquaporins

Popular Abstract in Swedish Biokemi, livets kemi, är den gren av naturvetenskapen som avhandlar de molekyler och kemiska processer som är nödvändiga för allt levandes existens. Genom att karakterisera livets molekyler och deras funktion vill man öka förståelsen kring vad som krävs för att en organism ska kunna leva, växa, fortplanta sig och anpassa sej till nya miljöer och förhållanden. Som biokem

The pedagogical dimension of internationalisation? – A challenging quality issue in higher education for the 21st century.

Abstract What are the pedagogical impacts of internationalisation on the development of higher education in Europe? How can we proceed in this process and take a pedagogical stance on the issue? This theoretical paper is partly based on a series of empirical studies conducted by the author, investigating students’ and teachers’ experiences and understanding of an internationalised educational cont