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Time synchronization is crucial for wireless sensor networks (WSNs), where operations often rely on time ordering of events. WSNs are deployed in different scenarios, and therefore their timing requirements are often related to the peculiar characteristics of the specific environment they have to act in. Synchronization is anyway always an issue: transactional applications need monotonicity of the

Melanocortin therapy by using adrenocorticotropic hormone (ACTH) or non-steroidogenic melanocortin peptides attenuates proteinuria and glomerular injury in experimental glomerular diseases and induces remission of nephrotic syndrome in patients with diverse glomerulopathies, even those resistant to steroids. The underlying mechanism remains elusive, but the role of melanocortin 1 receptor (MC1R) h

To what extent have public policies contributed to the innovation performance of Finland and Sweden in the period 1970-2013? This paper aims to assess the share of innovations stimulated by the public sector, specifically because of receiving public funding or being the result of research collaboration with public institutions. We combine survey and LBIO results on these variables, to overcome rep

Purpose: Construction waste is one of the larger waste streams in the developed world. Its environmental impact can be reduced by increased waste sorting. Waste sorting efficiency, however, is influenced by the characteristics of an evolving construction site with space limitation, changing layout, different waste streams over time, and the many different actors involved. This study explores facto

Introduction Reporting estimated glomerular filtration rate (eGFR) instead of serum concentrations is advised in current guidelines. Most creatinine-based eGFR equations for children require height, a parameter not readily available to laboratories. Combining height-dependent creatinine- and cystatin C-based eGFR improves performance. Recently, a height-independent creatinine-based eGFR equation h

Play is an enigmatic behaviour, the function of which is still debated, despite more than a century of research. We discuss the evolutionary function of play behaviour, focusing on the domestic dog (Canis familiaris), a unique species due to its past domestication and current cohabitation with humans. The ultimate function of play in dogs is explored through four main theories: 1) developing motor

Understanding how cancer cells regulate endocytosis during the cell cycle could lead us to capitalize this event pharmacologically. Although certain endocytosis pathways are attenuated during mitosis, the endocytosis shift and regulation during the cell cycle have not been well clarified. The conventional concept of glucose-regulated proteins (GRPs) as protein folding chaperones was updated by dis

Climate change impacts are a key challenge for sustainable urban development. To address this challenge, ecosystem-based adaptation (EbA), i.e., the use of ecosystem services and biodiversity to help people adapt to climate change, is increasingly being considered as an alternative or complement to traditional, engineering-based approaches (increasingly also known as nature-based solutions). Howev

Initiation and maintenance of several cancers including glioblastoma (GBM) may be driven by a small subset of cells called cancer stem cells (CSCs). CSCs may provide a repository of cells in tumor cell populations that are refractory to chemotherapeutic agents developed for the treatment of tumors. STAT3 is a key transcription factor associated with regulation of multiple stem cell types. Recently