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Schizophrenia - progressive and massive decline in response readiness by episodes

Objective: To relate the pattern of neuropsychological impairments among schizophrenic patients to case history data and disease characteristics in a cross-sectional study of unselected patients, and to integrate these data with two previous longitudinal studies of neuropsychological impairments among schizophrenic patients. Method: One hundred consecutive schizophrenic patients were studied with

Oxidation and reduction of pyridine nucleotides in alamethicin-permeabilized plant mitochondria

The inner mitochondrial membrane is selectively permeable, which limits the transport of solutes and metabolites across the membrane. This constitutes a problem when intramitochondrial enzymes are studied. The channel-forming antibiotic AlaM (alamethicin) was used as a potentially less invasive method to permearbilize mitochondria and study the highly branched electron-transport chain in potato tu

Trends of HIV-1 and HIV-2 prevalence among pregnant women in Guinea-Bissau, West Africa: possible effect of the civil war 1998-1999.

Objectives: Sentinel surveys in Bissau, the capital of Guinea-Bissau, have shown low prevalence of HIV-1 but high HIV-2 prevalence before 1998. Guinea-Bissau experienced a civil war in 1998-1999. To examine specifically the trends of HIV prevalence from antenatal surveys in Bissau, Guinea-Bissau in 1987-2004, and whether the civil war in 1998-1999 could have an effect on HIV prevalence levels afte

Aspects on coronary heart disease prevention in clinical practice

Prevention of first time disease or recurrence of coronary heart disease (CHD) is a major task for the health service. Guidelines regarding CHD prevention have been issued but studies have shown that treatment goals are inadequately met in clinical practice and there is urgent need for improved methods of implementation of guidelines. There is also a need for better risk stratification tools in or

An Emerging Product Approach in Environmental Law: Incorporating the life cycle perspective

Popular Abstract in Swedish Under senare år har produkternas roll uppmärksammats mer och mer inom miljöpolitiken. Det talas allt oftare om behovet av ett livscykeltänkande där produktens påverkan på miljön under olika faser av livscykeln blir en utgångspunkt för politiska åtgärder. I en värld där leverantörskedjorna ofta är långa och involverar aktörer i ett flertal länder kan ett livscykeltänkandOne of the noticeable trends in recent years is that products have received increasing attention in environmental policy. The focus on products and their life cycle impacts is often referred to as ?life cycle thinking?. This implies a shift away from the traditional focus on production processes and the environmental impacts of point-source pollution, towards a stronger focus on emissions from the

Interfaces in Self-Assembling Diblock Copolymer Systems: Characterization of Poly(isoprene-b-methyl methacrylate) Micelles in Acetonitrile

The kinetics of dipolar nonradiative energy transfer (DET) between dyes confined to the core−corona interface region of poly(isoprene-b-methyl methacrylate) block copolymers (PI−PMMA) in acetonitrile was analyzed using a new distribution model for energy transfer in spherical micelles. The distribution of block junction points was described by the model of Helfand and Tagami (HT) for the strong se

L22 ribosomal protein and effect of its mutation on ribosome resistance to erythromycin

The ribosomal protein L22 is a core protein of the large ribosomal subunit interacting with all domains of the 23 S rRNA. The triplet Met82-Lys83-Arg84 deletion in L22 from Escherichia coli renders cells resistant to erythromycin which is known as an inhibitor of the nascent peptide chain elongation. The crystal structure of the Thermus thermophilus L22 mutant with equivalent triplet Leu82-Lys83-A

Determination of Novel Borrelia Genospecies in Swedish Ixodes ricinus Ticks.

A total of 301 adult questing Ixodes ricinus ticks were collected at 15 different locations along the south and east coasts of Sweden to determine the Borrelia genospecies diversity. Thirty-two ticks (11%) were found to be positive by nested PCR with Borrelia burgdorferi sensu lato-specific primers. Species determination was based on partial sequencing of the 16S rRNA gene and the flagellin gene.

Quantum Optics and Quantum Information Processing in Rare-Earth-Ion-Doped Crystals

Popular Abstract in Swedish Ljusets minsta kända beståndsdelar kallas fotoner. Enligt kvantmekaniken har dessa egenskaper som normalt förknippas med vågor och samtidigt sådana egenskaper som normalt förknippas med partiklar. Partikelegenskaperna tar sig uttryck i att den minsta mängd ljus som går att mäta är den mängd som motsvaras av en foton. Vågegenskaperna, å andra sidan, visar sig i interfere

Expression and biological role of laminin-1.

Of the approximately 15 laminin trimers described in mammals, laminin-1 expression seems to be largely limited to epithelial basement membranes. It appears early during epithelial morphogenesis in most tissues of the embryo, and remains present as a major epithelial laminin in some adult tissues. Previous organ culture studies with embryonic tissues have suggested that laminin-1 is important for e

Euploidy in somatic cells from R6/2 transgenic Huntington's disease mice

Background: Huntington's disease (HD) is a hereditary neurodegenerative disorder caused by a CAG repeat expansion in the HD gene. The huntingtin protein expressed from HD has an unknown function but is suggested to interact with proteins involved in the cell division machinery. The R6/2 transgenic mouse is the most widely used model to study HD. In R6/2 fibroblast cultures, a reduced mitotic index