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The goal of this chapter is to provide an overview of key concepts related to modelling accident frequency, considering the random nature of traffic accidents. This includes topics such as the expected number of accidents (the 'true' yet unobserved measure of safety), regression-to-the-mean (RTM) and the safety-in-numbers phenomenon, which were briefly introduced in the chapter on accident data. T

Background/Objectives: Fertility-sparing surgery (FSS) is a standard practice for managing early stage cervical cancer, yet significant variation exists in clinical approaches worldwide. Our objective was to ascertain current practices and preferences for cerclage use among expert centers globally regarding FSS in patients with early stage cervical cancer. Methods: We conducted a cross-sectional s

Immune function varies widely across humans. Biological sex is a key factor underlying human immune variability, with men presenting with more severe infections and increased cancer rates, while women exhibit higher vaccine responses and prevalence of autoimmunity. Intrinsic biological sex differences arise from varying contributions of chromosomal sex, and sex hormone sensing and downstream signa

PurposeBlood culture collection with all bottles filled from a single venipuncture (single-sampling strategy, SSS) is increasingly used. More data on the effects of SSS on blood culture contamination is needed. After combined implementation of SSS and initial specimen diversion (ISDT) in our region, we evaluated the proportion of sampling events with at least four bottles, with growth of relevant

This paper assesses the communication and the use of climate scenarios at the science–science and science–policy interface in Finland, Sweden and Norway. It is based on document analysis and stakeholder questionnaires. The questionnaires targeted three stakeholder groups, all engaged in the communication and the use of climate scenario information: climate scenario producers; impact, adaptation an

Group exhibition. Participated with the work HEROES.Double Cheese Platter: Centenary of the Collection. Twenty Years of the Kunstmuseum StuttgartIn 1925, works from the City of Stuttgart art collection, then called the Städtische Gemäldesammlung (Municipal Painting Collection), were shown to the public for the first time in the Villa Berg. As the Galerie der Stadt Stuttgart (Stuttgart City Gallery

The co-occurrence of α-synuclein (αSyn) and Tau in synucleinopathies and tauopathies suggests a complex interplay between these proteins. Their cross-seeding enhances fibrillization, leading to the formation of diverse amyloid-specific structures enriched with β-sheets, which may influence their biological functions. However, existing tools cannot differentiate structural polymorphs directly in ce