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Heparan sulfate proteoglycans are proteins substituted with one or more heparan sulfate (HS) polysaccharides, found in abundance at cell surfaces. HS chains influence the activity of many biologically important molecules involved in cellular communication and signaling. The exostosin (EXT) proteins are glycosyltransferases in the Golgi apparatus that assemble HS chains on HSPGs. The EXTL3 enzyme m
Brain pericytes are important to maintain vascular integrity of the neurovascular unit under both physiological and ischemic conditions. Ischemic stroke is known to induce an inflammatory and hypoxic response due to the lack of oxygen and glucose in the brain tissue. How this early response to ischemia is molecularly regulated in pericytes is largely unknown and may be of importance for future the
As a novel coolant, the ethylene glycol-water (50 wt.%:50 wt.%) with graphene nanoplatelets nanofluids (GnP-EGW) were prepared at four weight concentrations (0.01, 0.1 0.5 and 1.0 wt.%), and heat transfer and pressure drop characteristics in a miniature plate heat exchanger (MPHE) were investigated. All nanofluid samples were prepared and diluted by ultrasonic vibration, and their thermal conducti
The chapter discusses the principle of legal separation of entities and its ramifications in the transnational human rights context. There have been calls to hold multinational enterprises accountable for human rights infringements in their global value chains. Some argue that lead firms should be subjected to a legal obligation of due diligence that would compel them to oversee subsidiaries and c
BACKGROUND: There is a lack of information on positive work factors among health care workers. OBJECTIVE: To explore salutogenic work-related factors among primary health care employees. METHOD: Questionnaire to all employees (n = 599) from different professions in public and private primary health care centers in one health care district in Sweden. The questionnaire, which had a salutogenic persp
III-V semiconductor nanowires have attracted extensive research interests over the past few decades due to their unique geometry and great potential for promoting new functionalities in future electronics, light-emitting diodes and solar cells. However, in order to push this technology beyond the laboratory level, it is essential to combine it with the current Si-based semiconductor industry for a
In Swedish historical archaeology, studies of towns have diverged from definition to deconstruction. In landscape studies the existence of occasional similar expressions of power in rural contexts as in towns is stressed. Another observation is that towns can display vague forms of urbanity, with lack of dense settlement and varied economy, as well as showing agrarian affiliations. A focus on sing
Recent statistics on language diversity among pupils in Swedish secondary school classrooms show that 24% have another L1 than Swedish. Thus, classrooms are multilingual spaces. In the English subject, an 'English Only' ideology dominates, where classrooms are exclusively English-medium, an ideology endorsed by educational policy, agencies like the Swedish Schools Inspectorate, and teacher educato
