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The Euro50 is a telescope for optical and infrared wavelengths. It has an aspherical primary mirror with a size of 50 meters and 618 segments. The optical configuration is of Gregorian type and the secondary mirror is deformable for adaptive optics. Observations can take place in prime focus, Gregorian foci, and Nasmyth foci using additional relay mirrors. The telescope provides seeing limited obs

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Identification of the causes of past climate change requires detailed knowledge of one of the most important natural factors—solar forcing. Prior to the period of direct solar observations, radionuclide abundances in natural archives provide the best-known proxies for changes in solar activity. Here we present two independent reconstructions of changes in solar activity during the last 1000 yr, wh

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With a surface wave method to estimate shear-wave velocity (Vs) from dispersion curve(s) of known mode(s), accurate modal identification is obviously a crucial issue. In this regard, the dispersion imaging method is an essential processing tool as it can unfold the multi-modal nature of surface waves through direct wavetield transformations. When a combined dispersion curve of an extended frequenc

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The objective of this study was to examine the effects of heparan sulfate (HS) on factors involved in the remodeling of connective tissue observed in patients with fibrotic respiratory disorders such as asthma. A suitable working model is to stimulate human fetal lung fibroblasts in vitro with structurally different forms of HS. Highly sulfated and iduronic acid (IdoUA)-rich HS specifically decrea

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The Chemotaxis Inhibitory Protein of Staphylococcus aureus (CHIPS) binds and blocks the C5a receptor (C5aR) and formyl-peptide receptor (FPR). This way, CHIPS is a potent inhibitor of the immune cell recruitment associated with inflammation. Truncation of the protein and the introduction of mutations, shifts the expression towards the insoluble fraction of Escherichia coli, whereas the wild-type p

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Simulations of one maritime and four continental observed cases of deep convection are performed with the Hebrew University Cloud Model that has spectral bin microphysics. The maritime case is from observations made on 18 September 1974 during the Global Atmospheric Research Program's Atlantic Tropical Experiment ( GATE). The continental storm cases are those of summertime Texas clouds observed on