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Background: Colour differences in photographs can be enhanced using a digital image-processing technique called LYYN. Objective: To investigate colour changes in the histamine wheal after skin prick tests (SPTs). Methods: Histamine SPTs were performed on the forearm of six medical students, and the reactions of the skin were photographed every 2 min for 30 min. Colour differences in the photograph

A large number of disease-causing mutations have been identified from several protein kinases. KinMutBase is a comprehensive knowledge base for human disease-related mutations in protein kinase domains (http://bioinf.uta.fi/KinMutBase/). The latest version contains 582 different mutations for 1,790 cases in 1,322 families. KinMutBase entries are described on the DNA, mRNA, and protein level. Numbe

All scientific research requires problem definition and discipline, as well as concept and method formation. However, from a human point of view the most important problems are probably those found in areas where it may be difficult to provide such ideal research conditions. Rehabilitation engineering and design research is one such field. Nonetheless, we believe that these theory and method forma

Does a rising tide lift all boats? This question – that is, to what extent does improvements of the general economy benefit all – is central to the study of economics and history. From fundamental issues about whether market forces have an innate tendency to increase or decrease differences in economic outcomes, to much debated questions about the effects of government policies, distributional con

Objectives. Surgical sites infections are very expensive and the total costs for coronary artery bypass grafting (CABG) surgery followed by deep sternal wound infection (DSWI) with conventional therapy are estimated to be 2.8 times that for normal, CABG surgery. Promising results have been reported with vacuum-assisted closure (VAC) therapy in patients with DSWI. This study presents the cost of VA

Dialysis patients often suffer from cardiovascular dis- eases, motivating the use of continuous monitoring of car- diac activity in clinical routine. Cardiac pressure pulses propagate through the vascular system and enter the ex- tracorporeal blood circuit of a dialysis machine, where the pulses are captured by pressure sensors. The cardiac pulses are obscured by the much stronger pressure pulses

The activated sludge process is the main process in most urban wastewater treatment systems. It is considered complex in nature, and building its mathematical model in practice becomes difficult. A simple and easy way to build the simulation models for the system is needed. In this paper, a LabVIEW based simulator for the system is presented. LabVIEW offers a highly efficient, simple and flexible

Calcitonin gene-related peptide (CGRP) is expressed throughout the CNS and peripheral nervous system, consistent with control of vasodilatation, nociception, motor function, secretion and olfaction. alphaCGRP is prominently localized in primary afferent C and Adelta fibres of spinal and trigeminal ganglia. Activation of the trigeminal nerve results in antidromic release of CGRP, acting through a C

Imaging the orientations of crystallites in bone requires the usage of synchrotron X-ray radiation, which is a limited resource for researchers. Thus scans have historically been limited to either small regions or few samples. In the present study, we scan 16 full frontal cross sections of mouse femora. This makes it possible to study structure, orientation, and composition, statistically across m

Major Depressive Disorder (MDD) is a leading global health challenge, affecting nearly 5% of the population. Mounting evidence suggests that systemic low-grade chronic inflammation (SLGCI) plays a central role in the development and progression of MDD. This persistent inflammatory state results from unresolved immune activation and sustained exposure to modern lifestyle factors, such as sedentary

The selective oxidation of alcohols to corresponding carbonyl compounds is essential in academia and industry. Benzil and BHMF have emerged as important classes of carbonyl compounds that have shown promising applications in materials and drug intermediates, especially in sustainable bio-based plastics. The traditional selective oxidation process generally uses equivalent amounts of oxidants or to

Throughout the last decades, the social responsibility of corporations has undergone significant changes. From revolving around self-regulation, voluntariness, and soft law, the regulatory landscape has expanded to involve harder demands on corporations, such as mandatory sustainability due diligence. This thesis considers these changes as a hardening of Corporate Social Responsibility (CSR), and