Sökresultat

Thrombotic microangiopathy is the pathological lesion found in hemolytic uremic syndrome (HUS), thrombotic thrombocytopenic purpura (TTP) as well as other conditions. It manifests as damaged endothelial cells in small vessels with deposits of platelet plugs, occlusion of vessels, decreased blood flow and secondary organ insufficiency. HUS is characterized by microangiopathic hemolytic anemia, thro

Primary defence against invading microorganisms depends on a functional innate immune system and the complement system plays a major role in such immunity. Deficiencies in one of the components of the complement system can cause severe and recurrent infections, systemic diseases, such as systemic lupus erythematosus (SLE) and renal disease. Screening for complement deficiencies in the classical or

Sequential Monte Carlo (SMC) methods have demonstrated a strong potential for inference on the state variables in Bayesian dynamic models. In this context, it is also often needed to calibrate model parameters. To do so, we consider block maximum likelihood estimation based either on EM (Expectation-Maximization) or gradient methods. In this approach, the key ingredient is the computation of smoot

BACKGROUND: Vascular endothelial dysfunction, accelerated thickening of arterial intima, and changes in ventricular repolarization contribute to increased cardiovascular morbidity in type 1 diabetes (T1D). Although vitamin C has important antioxidant functions and increased oxidative stress is a central mechanism of cardiovascular dysfunction in T1D, the relation between vitamin C and the cardiova

BACKGROUND: Retinoic acid (RA) and fibroblast growth factor 4 (FGF4) signaling control endoderm patterning and pancreas induction/expansion. Based on these findings, RA and FGFs, excluding FGF4, have frequently been used in differentiation protocols to direct differentiation of hESCs into endodermal and pancreatic cell types. In vivo, these signaling pathways act in a temporal and concentration-de

In the article, the issue of environmental sustainability criteria in the coffee sector is researched. Such important aspects in this topic are highlighted and discussed as reasons for the emergence of sustainability criteria for coffee and factors that make the production of coffee sustainable. Two widely used sustainability standards for coffee, the Fair Trade Coffee sustainability standard and

Energy efficient wood frame buildings give besides a number of positive effects also risks for moisture damages. To avoid moisture damage in wood houses some parts of the Swedish construction industry use WUFI 1D calculation tool in the design phase. The purpose of this study is to demonstrate the coupling between measured and WUFI 1D calculated values of relative humidity and temperature. The fir

Osmotic processing can be a very useful processing step in today’s food industry enabling the production of high quality natural food ingredients out of plant tissues. The maintenance of high product quality is quite product specific with regard to quality attributes. These attributes include fresh/like appearance, taste, texture and composition. Modern manufacturing trends and legislation regardi

The third generation (3G) cellular networks are starting to be deployed around the world. These networks are predicted to bring a vast number of IP enabled cellular terminals to the Internet. The limited address space of the current version of IP in the Internet, IPv4, has made the cellular industry decide to use IPv6 for these terminals. However, their success will largely depend on the availabil

Popular Abstract in Swedish Avhandlingen behandlar den svenska fotbollens kulturhistoria från 1800-talets slut fram till år 1950. Det är berättelsen om hur spelet gradvis etableras, överkommer en mängd inre och yttre problem och konflikter, för att träda in i sin guldålder under 1940-talet. Mer konkret följs hur fotbollens medelklassdominerade maktelit försökte kontrollera skeendet inom en sport pThis thesis concerns Swedish football´s cultural history from the end of the nineteenth century to 1950. It is the story of how the game was gradually established, and overcame a great number of internal and external problems and conflicts, before entering its sporting and cultural golden age during the 1940s. I demonstrate how this game´s middle-class dominated power elite tried to control the de