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Freshly thawed and continuously cultured human bone marrow-derived mesenchymal stromal cells comparably ameliorate allergic airways inflammation in immunocompetent mice

Recent data suggest that freshly thawed previously frozen mesenchymal stromal cells (MSCs) may not have the same effectiveness or breadth of anti-inflammatory activities as do continuously cultured MSCs. This has significant implications for clinical use, in which many infusion schemes use frozen cells thawed at the bedside for administration. The available data, however, predominantly evaluate in

Automatic Gleason grading of H&E stained microscopic prostate images using deep convolutional neural networks

Prostate cancer is the most diagnosed cancer in men. The diagnosis is confirmed by pathologists based on ocular inspection of prostate biopsies in order to classify them according to Gleason score. The main goal of this paper is to automate the classification using convolutional neural networks (CNNs). The introduction of CNNs has broadened the field of pattern recognition. It replaces the classic

Psychoacoustics and hallucinating schizophrenics. A psychobiological approach to schizophrenia

Popular Abstract in Swedish Psykoakustik och hallucinerande schizofrena Hallucinationer för hörseln är ett stort problem vid schizofreni. Många har försökt förklara men ingen lyckats. Denna avhandling påvisar avvikelser vid schizofrenisjukdomen vilka kan utgöra grundstenar för framtida förståelse av detta plågsamma symptom. Vad är psykoakustik ? Psykoakustik kan beskrivas som psykofysiska studie

A quantitative study of the P/E ratio on the Swedish market

Title: A quantitative study of the P/E ratio on the Swedish market Seminar date: June 4th, 2007 Course: Master thesis in Business and Finance and Economics, 10 Swedish Credits (15 ECTS) Authors: Filip Lundberg and Karl Johan Kulling Tutor: Hossein Asgharian Key words: P/E ratio, dividend yield, interest rate, risk, growth, debt to equity, market value, market to book, regression analysis and Swedi

Hylluppställning och användarbeteende i en skönlitterär samling : en fallstudie av Lunds stadsbibliotek

The aim of this thesis was to look closer into the shelf arrangement and user behavior in a fiction collection with the municipal library in Lund as an example. The purpose was to investigate to what extent the shelf arrangement in this library is adapted to the behavior of users when it comes to searching for and choosing fiction. The study is mainly focused on the division between Hc- and Hce-cl

Fostering buyer-supplier relationships An analysis of the supplier perspective in offshoring to China

This papers aims at analysing Chinese suppliers’ expectations of interfirm relationship when Western companies offshore their production to China. The research is motivated by the underrepresentation of the Chinese suppliers’ perspective in the literature and the undisputed role of China as the second most popular destination for offshoring. The literature finds that a successful relationship betw

Multivariate selection and the making and breaking of mutational pleiotropy

The role of mutations have been subject to many controversies since the formation of the Modern Synthesis of evolution in the early 1940ties. Geneticists in the early half of the twentieth century tended to view mutations as a limiting factor in evolutionary change. In contrast, natural selection was largely viewed as a “sieve” whose main role was to sort out the unfit but which could not create a

Pharmacological Medical Treatment of Epilepsy in Patients with Dementia : A Systematic Review

Background: Patients with dementia have an increased risk of developing epilepsy, es-pecially in patients with vascular dementia and Alzheimer’s disease. In selecting the optimal an-ti-epileptic drug (AED), the possible side effects such as drowsiness and worsening of cognitive function should be taken into consideration, together with co-morbidities and type of epilepsy. Objective: The current sy

Transients from ONe white dwarf - neutron star/black hole mergers

We conduct the first 3D hydrodynamic simulations of oxygen-neon white dwarf-neutron star/black hole mergers (ONe WD-NS/BH mergers). Such mergers constitute a significant fraction, and may even dominate, the inspiral rates of all WD-NS binaries. We post-process our simulations to obtain the nuclear evolution of these systems and couple the results to a supernova spectral synthesis code to obtain th

Implementation of a standardized HIPEC protocol improves outcome for peritoneal malignancy

BACKGROUND: Experience with Cytoreductive Surgery (CRS) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in a pioneer hospital resulted in a treatment protocol that has become the standard in the Netherlands. Outcome of CRS and HIPEC was reviewed to assure differences between the pioneer phase and the period wherein the Dutch HIPEC protocol was clinically implemented.METHODS: The first consec