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We examine socioecological drivers of nutrient overloading and eutrophication in the Chesapeake Bay associated with poultry production on the Delmarva Peninsula. We use a social metabolic analysis—rooted in a political-economy perspective—that highlights the interchange of matter and energy and the inextricable links within and between social and ecological systems, illuminating the social structu

This open issue is published against the background of a major global pandemic. The old ‘normal’ seems far away and undesirable, as a socio-ecological transformation becomes even more urgent. The contributions featured here scrutinize the current trends in the capitalist mode of production and envision the alternative organization of our societies. They examine new configurations of work, to which

Urea is a very attractive chemical raw material for large-scale production as it combines low cost with virtually unlimited supply and essentially no toxic effects. Here, we present a study on its use in the dehydration of trimethylolpropane with formation of 3-ethyl-3-(hydroxymethyl)oxetane. The reaction consists of carbonylation of trimethylolpropane and subsequent extrusion of carbon dioxide. T

The unsurpassed versatility of heat sensitive biosensors is illustrated by various new applications of the flow-calorimetric biosensor system, the enzyme thermistor (ET) developed in our laboratory. The ET measures the reaction heat in a small column containing immobilized biocatalyst. Since most biological reactions are exothermic, the ET has a very broad applicability and numerous assays of clin

The aim of this thesis is to investigate the changes in vasoactive intestinal peptide (VIP) and calcitonin gene-related peptide(CGRP) and P2Y6-mediated signaling following experimental subarachnoid hemorrhage (SAH) and transient middle cerebral artery occlusion (tMCAO). VIP and CGRP are among the most powerful vasodilators known to man while P2Y6 mediates strong vasoconstriction in cerebral blood

Blodet bär med sig syre och näringsämnen som är vitala för vävnadens överlevnad, och därför är karakterisering av hjärnans blodförsörjning av stor betydelse. Blodflödet i kapillärerna kallas för perfusion. Vid MRI-baserad perfusionsmätning i hjärnan utnyttjas ofta signalförändringar orsakade av ett spårämne i blodet. Spårämnet kan antingen skapas internt genom märkning av det arteriella inflödet a

A new polynomial formulation of variable step size linear multistep methods is presented, where each k-step method is characterized by a fixed set of k-1 or k parameters. This construction includes all methods of maximal order (p=k for stiff, and p=k+1 for nonstiff problems). Supporting time step adaptivity by construction, the new formulation is not based on extending classical fixed step size me

Calcitonin gene-related peptide (CGRP) is a 37 amino acid neuropeptide with several functions including vasodilation, the perception of painful stimuli, and inflammation. The CGRP receptor consists of two main components; calcitonin-like receptor (CLR) and receptor activity-modifying protein 1 (RAMP1). While there is a growing recognition that CGRP plays a key role in migraine, the function of CGR

The simulation of viscous, compressible flows around complex geometries or similar applications often inherit the task of solving large, stiff systems of ODEs. Domain-based implicit-explicit (IMEX) type schemes offer the possibility to apply two different schemes to different parts of the computational domain. The goal hereby is to decrease the computational cost by increasing the admissible step

Today, there is an increased realization that engaging with Paralympic athletes offers the chance for healthcare professionals to work at the intersection of rehabilitation with sports and exercise medicine. The study of both injury and illness epidemiology in Paralympic sport is important, as findings may assist in the formulation of prevention strategies. A model for the systematic development o