Filtyp
Most available methods for detecting single nucleotide polymorphisms (SNPs) are based principally on the system that can produce an increased fluorescence signal during hybridization. In the current study, we demonstrate a method of base-quenched probe for polymerase chain reaction (PCR) genotyping that requires only a pair of primers and one fluorescent probe and does not invariably depend on the
This article describes and explains the movement of female relative wages in Sweden from 1920 to 1995. During this period the aggregate gender wage gap shrunk from 41 to 15%. The bulk of the change took place in two periods: 1920 to 1940 and 1960 to 1980. With regard to determining factors, the analysis distinguishes between the period before 1960, when the rise in the female relative wage was the
BACKGROUND AND PURPOSE: Preeclampsia is a major obstetric problem of unknown etiology. The fact that removal of the placenta is the only cure for preeclampsia, has led to the well-established hypothesis, that the placenta is central in the etiology. Gene profiling and proteomics studies have suggested oxidative stress caused by reperfusion and free oxygen radicals as a potential pathophysiological
BackgroundSocial function is a key aspect of health‐related quality of life after solid organ transplantation (SOT). The focus of this study was to report how solid organ‐transplanted patients change their social function after transplantation.AimTo investigate the main concerns associated with social function after SOT and how solid organ transplant recipients (SOTRs) deal with these concerns.Met
This study examined retirement decisions among people who had left working life before 65 years of age and those working beyond 65 years in an extended working life. The results were used to make a model about their considerations, weighting and decision making, and important factors and themes in working beyond 65 years of age or retiring before 65. The interviewees seemed to have considered and
Summary: Reduction of the cerebral perfusion pressure caused by vessel occlusion or stenosis is a cause of neurological symptoms and border-zone infarctions. The aim of this article is to describe perfusion patterns in hemodynamic stroke, to give a practical approach for the assessment of colour encoded CT- and MR-perfusion maps and to demonstrate the clinical use of comprehensive imaging in the w
In Europe, land use changes follow public policies, and particularly the Common Agricultural Policy. To predict the effect of policies on agricultural practices, landscape, and ultimately biodiversity, requires understanding of the interactions between social, economic and ecological dynamics at regional scale. We studied by means of prospective scenarios the possible effects of agricultural chang
Infective endocarditis (IE) caused by bacteria within Haemophilus (excluding Haemophilus influenzae), Aggregatibacter, Cardiobacterium, Eikenella and Kingella (HACEK) is rare. This study aimed to describe clinical features of IE caused by HACEK genera in comparison with IE due to other pathogens. Cases of IE due to HACEK were identified through the Swedish Registry of Infective Endocarditis (SRIE)
IntroductionEmerging evidence suggests a difference in access to facilities for medical termination of pregnancy (MTP) and delivery among women in different regions of the country. However, we lack assessments at a large scale across all geographies. Our study aims to describe the percent contribution of private and public sectors in institutional deliveries and MTP in India.MethodsA secondary dat
Background: The incidence of detected ductal carcinoma in situ (DCIS) continues to increase and now accounts for 14% of all breast cancer, and 20%–25% of screen-detected cases. Treatment trends of DCIS are important in order to inform the ongoing debate about possible overdiagnosis and overtreatment, but have not been investigated for over a decade in Australia and New Zealand. Against this backgr
AIMS: Diabetic peripheral neuropathy (DPN) is a common and severe complication to type 2 diabetes (T2D). The pathogenesis of DPN is not fully known, but several pathways and gene polymorphisms contributing to DPN are described. DPN can be studied using nerve biopsies, but studies on the proteome of the nerve itself, and its surrounding tissue as a whole, are lacking. Studies on the posterior inter
Background: Over the past decade, the miniaturisation of animal borne tags such as geolocators and GPS-transmitters has revolutionized our knowledge of the whereabouts of migratory species. Novel light-weight multi-sensor loggers (1.4g), which harbour sensors for measuring ambient light intensity, atmospheric pressure, temperature and acceleration, were fixed to two long-distance migrant bird spec
Individualization of therapy based on a person’s specific type of diabetes is one key element of a “precision medicine” approach to diabetes care. However, applying such an approach remains difficult because of barriers such as disease heterogeneity, difficulties in accurately diagnosing different types of diabetes, multiple genetic influences, incomplete understanding of pathophysiology, limitati
As messaging applications are becoming increasingly popular, it is of utmost importance to analyze their security and mitigate existing weaknesses. This paper focuses on one of the most acclaimed messaging applications: Signal. Signal is a protocol that provides end-to-end channel security, forward secrecy, and post-compromise security. These features are achieved thanks to a key-ratcheting mechan
Despite large industrial relevance, the relation between rotor-stator geometry, hydrodynamics and drop breakup is poorly understood, partly since no methods for measuring the fragmenting stresses acting on drops have been established. This study attempts to bridge this gap by developing, applying and evaluating two approaches for estimating local turbulent stresses based on particle image velocime
The aim of this paper is to enhance understanding of how the resilience of water, sanitation and hygiene (WASH) systems to hazards can be improved. In turn, this aims to inform different strategies for public and private partnerships (PPPs). In a new approach, to acknowledge the multi levelled nature of resilience; risk at the relevant levels are taken into account, (regional/river basin, urban ar
Populärvetenskaplig sammanfattning1,7 miljoner nya fall av bröstcancer diagnosticeras årligen i världen. Bröstcancer är kvinnans vanligaste tumörsjukdom och i västvärlden samt Sverige kommer var åttonde till var nionde kvinna att insjukna under sin livstid. Överlevnaden efter bröstcancer är bland de högsta i världen i Sverige, med femårsöverlevnad på cirka 90%. För de kvinnor som diagnosticeras i Most patients with breast cancer present with low-risk tumors, node-negative disease, and excellent prognosis. For these patients, routine axillary nodal staging by sentinel lymph node biopsy (SLNB) has no therapeutic benefit. For patients with limited sentinel lymph node metastasis, completion axillary nodal dissection is controversial. Furthermore, those with heavy-burden metastasis could benefi
