Sökresultat

Infantile malignant osteopetrosis (IMO) is a rare, recessive disorder characterized by increased bone mass caused by dysfunctional osteoclasts. The disease is most often caused by mutations in the TCIRG1 gene encoding a subunit of the V-ATPase involved in the osteoclasts capacity to resorb bone. We previously showed that osteoclast function can be restored by lentiviral vector-mediated expression

BACKGROUND: Colorectal carcinoma is one of the most common malignancies in the Western population, and a considerable proportion of colorectal carcinomas are estimated to have a familial background.METHODS: Individuals whose mothers were diagnosed with colon carcinoma or rectal carcinoma from 1958 to 1993, a total of 1. 48 million person-years, constituted the cohort of this Swedish population-bas

With aging populations, unequal access to care, and shortages of staff, healthcare systems today are facing many challenges. Technology advancements, with artificial intelligence (AI) in particular, have been one of the main drivers of innovation in multiple industries. Although the healthcare sector is moving slower compared to other industries, there is great potential for relieving healthcare w

Det har sagts att alla arkitekturepoker brukar nå sitt bottenmärke någonstans runt 30 år. Under en praktik på ett arkitektkontor upplevde jag det på egen hand när jag arbetade med ett område i Stockholm. Strategin för området är att riva stora delar av dess bebyggelse från 80- och 90-talet. Jag uppfattar strategin som ett uttryck för en allmän impopularitet av arkitekturen från denna period — den

A shareholder agreement is a contract between the owners of a company which regulates rights and obligations associated with being a shareholder. The contract differs from other contracts because it regulates corporate law issues. The purpose of the contract is often to avoid application of the freedom to transfer shares according to the Swedish Companies Act, by providing restrictions on the tran

Pufendorfinstitutet 2009 – 2019 En jubileumsskrift LUNDS UNIVERSITET Box 117 221 00 Lund Tel 046-222 00 00 www.pi.lu.se P U FE N D O R FIN S T IT U T E T 2 0 0 9 – 2 0 1 9 – E N JU B ILE U M S S K R IFT Pufendorfinstitutet 2009 – 2019 En jubileumsskrift LUNDS UNIVERSITET Box 117 221 00 Lund Tel 046-222 00 00 www.pi.lu.se P U FE N D O R FIN S T IT U T E T 2 0 0 9 – 2 0 1 9 – E N JU B ILE U M S S K

https://www.pi.lu.se/sites/pi.lu.se/files/jubileumsboken_hemsidan.pdf - 2026-07-20

With an increasing population, the demand for housing also increases. Due to renovation and retrofitting of the housing stock it is possible to give the future resident a modern housing and at the same time reduce the energy demand for the building. Reusing buildings is often a more sustainable way to develop housing because it results in less waste and lower carbon dioxide emissions compared to d

The JPL rover Perseverance's investigations of Jezero crater's floor reveal that the ultramafic Séítah formation and the overlying mafic Máaz formation are deformed into a broad, low-amplitude structural dome. Mastcam-Z stereo images processed into digital outcrop models, together with RIMFAX ground-penetrating radar profiles, were used to reconstruct the three-dimensional stratal geometry of both

Chronic suppurative otitis media (CSOM) is a long-term inflammatory disease of the middle ear that can cause persistent ear discharge and hearing loss. EarClean is an ear pipette intended to enable simple and cost-effective rinsing and cleaning of the ear canal. For safe clinical use, it is importantto evaluate whether the pressure generated during use may pose a risk of damaging the tympanic memb

Mantle cell lymphoma (MCL) after relapse is associated with poor prognosis. No standard of care exists and available evidence for treatments is limited, particularly in patients who fail Bruton tyrosine kinase inhibitor (BTKi) therapy. This multicentre retrospective chart review study, SCHOLAR-2, addresses this knowledge gap and reports on data collected from 240 patients with relapsed/refractory

We monitored northern bat Eptesicus nilssonii (Keyserling & Blasius, 1839) acoustically along a 27 km road transect at weekly intervals in 1988, 1989 and 1990, and again in 2016 and 2017. The methodology of data collection and the transect were the same throughout, except that the insect-attracting mercury-vapour street-lights along parts of the road were replaced by sodium lights between the

Calcareous nannofossils are considered to be the most productive calcifying organisms, but the impact of their emergence on the chemistry of the ocean in the Late Triassic is not understood yet. Evolutionary details of this bio-event are missing due to the scarcity of well-preserved outcrops worldwide. The current study focuses on the calcareous nannofossil assemblage of the middle Norian to lower

As part of the OP3 field study of rainforest atmospheric chemistry, above-canopy fluxes of isoprene, monoterpenes and oxygenated volatile organic compounds were made by virtual disjunct eddy covariance from a South-East Asian tropical rainforest in Malaysia. Approximately 500 hours of flux data were collected over 48 days in April-May and June-July 2008. Isoprene was the dominant non-methane hydro

Fe 0 fluorescence by PAR has been investigated in eight symbiotic starshaving a wide range in temperature of the hot component and orbitalperiod. The data used are spectra obtained from the IUE archive. Allpumping lines investigated in this work are in the short wavelengthregion of IUE (1200-2000 Å), except for He 0 λ 1084.942 andO 0 λ 1032.041. The resulting Fe 0 fluorescence lines are mainlyin t

Bone mineral density (BMD) assessed by DXA is used to evaluate bone health. In children, total body (TB) measurements are commonly used; in older individuals, BMD at the lumbar spine (LS) and femoral neck (FN) is used to diagnose osteoporosis. To date, genetic variants in more than 60 loci have been identified as associated with BMD. To investigate the genetic determinants of TB-BMD variation alon

The critically endangered Sumatran rhinoceros (Dicerorhinus sumatrensis) has, due to previous hunting and habitat loss, diminished to a few non-viable and fragmented populations. Despite a relatively large amount of conservation efforts during the last 30 years, numbers are still declining. Accurate numbers today are unknown, since the species is rare. Information indicates that less than 100 indi

Since its inception, Estonia has been at the forefront of innovation in terms of e-governance and applications of online systems into various aspects of Estonians’ lives. In 2014 Estonia opened up it’s digital borders and launched a digital economic citizenship - e-Residency - available to anyone in the world for using Estonian e-services to register and manage a company online. In May 2018, 5000