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Final report of Working Group 4: Ergonomics of thermal effects. A COST Action TU1101 / HOPE collaboration

The thermal effects related to wearing a bicycle helmet are complex and different studies have investigated single parts of this topic. A literature review was produced and published (Bogerd et al., 2015) summarizing the different findings to give a complete overview on this topic as well as to suggest new perspectives. Headgear increases head insulation and therefore is mainly problematic under w

Community and food web assembly on virgin habitat islands - The nunatak saga

Popular Abstract in Icelandic Landnám á jökulskerjum Plöntur hafa lengi verið taldar nauðsynlegar til að dýr geti numið land en þessi sýn er að breytast því rannsóknir hafa sýnt að smádýr nema oft land á undan plöntum. Landnám bæði plantna og dýra getur hafist um leið og nýtt land myndast en til að landnám takist þurfa nokkrir þættir að fara saman. Þau verða að komast á staðinn og þegar þangað erThe classical view of primary community assembly is that colonisation by plants is essential before invertebrates can establish. It has been recognised, however, that invertebrates can establish before plants, and that they may be important in the first steps of community assembly. Plant succession is well studied but assembly of invertebrates and how their dispersal abilities affect the community

Primary screening for human papillomavirus compared with cytology screening for cervical cancer in European settings: cost effectiveness analysis based on a Dutch microsimulation model

Objectives To investigate, using a Dutch model, whether and under what variables framed for other European countries screening for human papillomavirus (HPV) is preferred over cytology screening for cervical cancer, and to calculate the preferred number of examinations over a woman's lifetime. Design Cost effectiveness analysis based on a Dutch simulation model. Base case analyses investigated the

Palaeomagnetic, geochronological and geochemical study of Mesoproterozoic Lakhna Dykes in the Bastar Craton, India: Implications for the Mesoproterozoic supercontinent

Palaeomagnetic analysis of the Lakhna Dykes (Bastar Craton, India) yields a palaeopole at 36.6 degrees N, 132.8 degrees E, dp=12.4 degrees, dm=15.9 degrees, and the U-Pb zircon age obtained from one of the rhyolitic dykes is 1466.4 +/- 2.6 Ma (MSWD = 0.21, concordia age based on two analyses with identical Pb/U ages), similar to previously published U-Pb ages. Major and trace element analyses of t

Coreceptor usage of sequential isolates from cynomolgus monkeys experimentally infected with simian immunodeficiency virus (SIVsm)

Sequential isolates from eight cynomolgus monkeys experimentally infected with Simian immunodeficiency virus (SIVsm, of sooty mangabey origin) were tested for coreceptor use in the human osteosarcoma indicator cell line, GHOST(3), expressing CD4 and one or another of the chemokine receptors CCR3, CCR5, CXCR4, BOB, or the orphan receptor Bonzo. The indicator cell line carries the human immunodefici

Effects of Levosimendan on Right Ventricular Afterload in Patients with Acute Respiratory Distress Syndrome: a Pilot Study

OBJECTIVE: Acute respiratory distress syndrome (ARDS) is frequently associated with increased pulmonary vascular resistance and thus with systolic load of the right ventricle. We hypothesized that levosimendan, a new calcium sensitizer with potential pulmonary vasodilator properties, improves hemodynamics by unloading the right ventricle in patients with ARDS. DESIGN: Prospective, randomized, pla

Application of an atomic relaxation model for the interpretation of O1s to Rydberg excited Auger electron spectra of molecular oxygen

Resonant and normal Auger electron spectra associated with an O1s initial vacancy of the O-2 molecule have been recorded using photon energies of 541.80, 541.97 and 650 eV. The resonant Auger spectra obtained at 541.80 and 541.97 eV are interpreted as composed essentially of two characteristic parts, one between 10 and 35 eV binding energy reminiscent to direct photoionisation, and another, above

Positional and functional mapping of a neuroblastoma differentiation gene on chromosome 11

Background: Loss of chromosome 11q defines a subset of high-stage aggressive neuroblastomas. Deletions are typically large and mapping efforts have thus far not lead to a well defined consensus region, which hampers the identification of positional candidate tumour suppressor genes. In a previous study, functional evidence for a neuroblastoma suppressor gene on chromosome 11 was obtained through m

A new system for photon induced fluorescence spectroscopy applied to the study of doubly excited states of helium

A new system for photon induced fluorescence spectroscopy (PIFS) at the gas phase photoemission beamline (Elettra, Trieste) is described. It consists of a novel non-dispersive detector for VUV photons and a spectrometer for UV/visible light with cooled CCD detector. To illustrate the performance of the apparatus, the fluorescence decay of the doubly excited states of helium below the N = 2 ionizat

Sex Differences in the Methylome and Transcriptome of the Human Liver and Circulating HDL-Cholesterol Levels

Context: Epigenetics may contribute to sex-specific differences in human liver metabolism. Objective: To study the impact of sex on DNA methylation and gene expression in human liver. Design/Setting: Cross-sectional, Kuopio Obesity Surgery Study. Participants/Intervention: We analyzed DNA methylation with the Infinium HumanMethylation450 BeadChip in liver of an obese population (34 males, 61 femal

Revealing turning points in ecosystem functioning over the Northern Eurasian agricultural frontier

The collapse of the Soviet Union in 1991 has been a turning point in the World history that left a unique footprint on the Northern Eurasian ecosystems. Conducting large scale mapping of environmental change and separating between naturogenic and anthropogenic drivers is a difficult endeavor in such highly complex systems. In this research a piece-wise linear regression method was used for breakpo

Feeding Honeybee Colonies with Honeybee-Specific Lactic Acid Bacteria (Hbs-LAB) Does Not Affect Colony-Level Hbs-LAB Composition or Paenibacillus larvae Spore Levels, Although American Foulbrood Affected Colonies Harbor a More Diverse Hbs-LAB Community

The main current methods for controlling American Foulbrood (AFB) in honeybees, caused by the bacterial pathogen Paenibacillus larvae, are enforced incineration or prophylactic antibiotic treatment, neither of which is fully satisfactory. This has led to an increased interest in the natural relationships between the pathogenic and mutualistic microorganisms of the honeybee microbiome, in particula

Intracranial bleeding due to vitamin K deficiency : Advantages of using a pediatric intensive care registry

Aim: To determine the incidence of late intracranial vitamin K deficiency bleeding (VKDB) in The Netherlands using the Dutch Pediatric Intensive Care Evaluation (PICE) registry. Methods: The PICE registry was used to identify all infants who were admitted to a Dutch pediatric intensive care unit (PICU) with intracranial bleeding between 1 January 2004 and 31 December 2007. Cases of confirmed late

Multicentre age-related reference intervals for cerebrospinal fluid serine concentrations : Implications for the diagnosis and follow-up of serine biosynthesis disorders

The disorders of serine biosynthesis are a group of inborn errors of metabolism characterised by congenital microcephaly, seizures and severe psychomotor retardation. Although these disorders are rare the prompt recognition of serine deficiency is important as these disorders are treatable. The diagnosis is based on decreased concentrations of serine in cerebrospinal fluid (CSF). It has previously

Dynamical suppression of atomic peaks in resonant dissociative photoemission

Resonant excitation to the F1s-σ* dissociative state in hydrogen fluoride gives a photoelectron spectrum where the spectator part contains strong atomic lines but a participator part where such lines are lacking. We demonstrate that this contrasting behaviour between the two parts is due to a strong dynamical suppression of the resonant contribution, making direct main state photoionization the do

Femtosecond dissociation of ozone studied by the Auger Doppler effect

The peaks arising from the decay of the excited oxygen atom were studied. Fast dissociation of core-excited ozone was confirmed by the presence of Auger emission from atomic oxygen in the decay spectrum from the ozone OT 1s-σ*(7a1) state. No such emission was observed after excitation of the corresponding state on the central oxygen atom. An angle-dependent energy shift of the atomic lines was obs