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Addressees are sensitive to the presence of gesture when tracking a single referent in discourse

Production studies show that anaphoric reference is bimodal. Speakers can introduce a referent in speech by also using a localizing gesture, assigning a specific locus in space to it. Referring back to that referent, speakers then often accompany a spoken anaphor with a localizing anaphoric gesture (i.e., indicating the same locus). Speakers thus create visual anaphoricity in parallel to the anaph

Islamic Modernities in Southeast Asia. Exploring Indonesian Popular and Visual Culture, by Leonie Schmidt

In Islamic Modernities in Southeast Asia, Leonie Schmidt provides a thorough analysis of contemporary Islamic-themed popular and visual cultures, mainly in Indonesia. This book is an essential read for those who wish to understand multiple modernities unfolding in post-1998 Indonesia (the Reformasi era). By using the term Islamic, she refers to any ‘cultural practices that are considered bernafask

Sexual dimorphism in a top predator (Notophthalmus viridescens) drives aquatic prey community assembly

Intraspecific variation can have important consequences for the structure and function of ecological communities, and serves to link community ecology to evolutionary processes. Differences between the sexes are an overwhelmingly common form of intraspecific variation, but its community-level consequences have never been experimentally investigated. Here, we manipulate the sex ratio of a sexually

Convection-diffusion-reaction and transport-flow problems motivated by models of sedimentation: some recent advances

The sedimentation of a suspension is a unit operation widely used in mineral processing, chemical engineering,wastewater treatment, and other industrial applications. Mathematical models that describe these processes and may be employed for simulation, design and control are usually given as nonlinear, time-dependent partial differential equations that in one space dimension include strongly degen

From genes to blooms : Diversity in microcystin phenotypes and mcy biosynthesis genes in the cyanobacterium Microcystis

Cyanobakterier är urgamla prokaryoter, som finns i en mängd olika livsmiljöer över hela världen. Deras förmåga att utföra fotosyntes (det vill säga att använda solljus, vatten och koldioxid för att producera syre- och kolhydrater) gör dem till viktiga primära producenter, och tillsammans med andra växtplankton utgör de basen för akvatiska näringsvävar.Vid optimala tillväxtförhållandena kan populatCyanobacterial blooms are increasing in occurrence and frequency world-wide, mainly due to eutrophication and increased water temperatures. In freshwater, Microcystis is one of the most common bloom-forming genera, renowned for producing the toxin microcystin which is harmful to humans and other mammals. The ability of Microcystis strains to produce microcystins is largely due to the presence or a

Identification and validation of NFIA as a novel prognostic marker in renal cell carcinoma

Prognostic tools are an essential component of the clinical management of patients with renal cell carcinoma (RCC). Although tumour stage and grade can provide important information, they fail to consider patient- and tumour-specific biology. In this study, we set out to find a novel molecular marker of RCC by using hepatocyte nuclear factor 4A (HNF4A), a transcription factor implicated in RCC pro

Hypomyelination and reversible white matter attenuation in 3-phosphoglycerate dehydrogenase deficiency

White matter abnormalities are a feature of many inborn errors of metabolism and magnetic resonance imaging (MRI) of the brain has become an important tool in the diagnostic workup of these disorders. Recently, patients were reported with a potentially treatable disorder of serine biosynthesis. They presented with congenital microcephaly, severe psychomotor retardation and intractable seizures. Lo

Fatal cerebral edema associated with serine deficiency in CSF

Two young girls without a notable medical history except for asthma presented with an acute toxic encephalopathy with very low serine concentrations both in plasma and cerebrospinal fluid (CSF) comparable to patients with 3-phosphoglycerate dehydrogenase (3-PGDH) deficiency. Clinical symptoms and enzyme measurement (in one patient) excluded 3-PGDH deficiency. Deficiencies in other serine biosynthe

Recursive focus prosody

This paper presents results of a production experiment testing the recursivity of prosodic realization of focus in Tokyo Japanese. Tokyo Japanese wh-questions obligatorily exhibit focus prosody, which starts from a wh-phrase (WH) and continues until the question particle (Q) that binds the wh-phrase (Deguchi and Kitagawa 2002; Ishihara 2002, 2003). The current study examines the case where one WH–

2012/13 influenza vaccine effectiveness against hospitalised influenza A(H1N1)pdm09, A(H3N2) and B : estimates from a European network of hospitals

While influenza vaccines aim to decrease the incidence of severe influenza among high-risk groups, evidence of influenza vaccine effectiveness (IVE) among the influenza vaccine target population is sparse. We conducted a multicentre test-negative case–control study to estimate IVE against hospitalised laboratoryconfirmed influenza in the target population in 18 hospitals in France, Italy, Lithuani

Development and Validation of Decision Rules Models to Stratify Coronary Artery Disease, Diabetes, and Hypertension Risk in Preventive Care : Cohort Study of Returning UK Biobank Participants

Many predictive models exist that predict risk of common cardiometabolic conditions. However, a vast majority of these models do not include genetic risk scores and do not distinguish between clinical risk requiring medical or pharmacological interventions and pre-clinical risk, where lifestyle interventions could be first-choice therapy. In this study, we developed, validated, and compared the pe

Experiences with the narrow gap undulator at MAX-lab

An undulator with short poles (period 24 mm) and extremely narrow gap (magnet gap 7.7 mm) using a squeezable vacuum chamber has been installed and is in operation at the MAX-lab 550 MeV storage ring. The device operates with a vacuum chamber aperture down to 6.2 mm. The behaviour of the storage ring concerning lifetime, emittance, tune shift and closed orbit is well described by conventional model

ERP studies of visual and auditory processing of negated sentences

In two event-related potential studies, we investigated the processing of sentences with prefixal negation (unauthorized), sentential negation (not authorized) and no negation (authorized). We asked whether prefixal and sentential negation resulted in delayed processing. In Experiment 1, sentences such as “The White House announced that the new Obama biography was authorized/unauthorized/not autho

Hyperthyroidism as a late effect in childhood cancer survivors - an Adult Life after Childhood Cancer in Scandinavia (ALiCCS) study

Background: Hyperthyroidism is a rare disorder which may negatively affect health and quality of life. Its occurrence in childhood cancer survivors has not previously been investigated in detail. Material and methods: In the hospital registers of the five Nordic countries, 32,944 childhood cancer survivors and 212,675 population comparisons were followed for the diagnosis of hyperthyroidism. Hospi