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(+)-5,6-Epoxy-bicyclo[2.2.1]heptane-2-one, (+)-1, and endo-(−)-5,6-epoxy-bicyclo[2.2.1]heptane-2-ol, endo-(−)-2, were obtained by kinetic resolution of rac-1 by asymmetric bioreduction catalyzed by whole cells of a genetically engineered Saccharomyces cerevisiae yeast strain. The strain, TMB4100, had 1% phosphoglucose isomerase (PGI) activity and overexpressed a specific short-chain dehydrogenase,

This article deals with copyright regulation meeting the quite rapid societal changes associated with digitization, and it does so by reinterpreting Karl Renner's classical texts in the light of contemporary cognitive theory of conceptual metaphors and embodiment. From a cognitive theory perspective, I focus on the notion that the legal norms only appear to be unchanged—the Renner distinction betw

Human telomerase reverse transcriptase (TERT) encodes a rate-limiting catalytic subunit of telomerase that maintains genomic integrity. TERT expression is mostly repressed in somatic cells with exception of proliferative cells in self-renewing tissues and cancer. Immortality associated with cancer cells has been attributed to telomerase over-expression. The precise mechanism behind the TERT activa

Group G streptococcus (GGS) is a human bacterial pathogen expressing surface proteins FOG and protein G (PG) which interact with several host defense systems, including the complement and contact systems. Selected reaction monitoring mass spectrometry, electron microscopy, and protein binding assays were used to follow the amounts of FOG and PG intracellularly and on the bacterial surface during d

We introduce partially defined dynamical systems defined on a topological space. To each such system we associate a functor s from a category G to Topop and show that it defines what we call a skew category algebra A ⋊ G. We study the connection between topological freeness of s and, on the one hand, ideal properties of A ⋊ G and, on the other hand, maximal commutativity of A in A ⋊ G. In particul

During the last decade women in Sweden have reduced men’s lead in participation in mathematics education and in professional careers as mathematicians. However, the development is uneven and slow overall. In some areas and at the highest levels women have increased their participation only marginally. Why, one may ask, is progress so slow after almost twenty years of active work from the Women and

This proposal, by a Working Group of Integration of ice-core, marine, and terrestrial records (INTIMATE) and the Subcommission on Quaternary Stratigraphy (SQS) of the International Commission on Stratigraphy (ICS), is for a formal subdivision of the Holocene Series/Epoch. Although previous attempts to subdivide the Holocene have proved inconclusive, recent developments in Quaternary stratigraphy,

The aim of this article is to contribute to the literature on how stratification affects professions. Our case study is the ‘first teacher reform’ in Sweden, which introduced a more prominent position for some teachers. In this article, we elaborate six different first teacher types and analyse how these affect the profession. While elites are generally described as hybrids, we conclude that sever

The article analyses a case of prosecution for human smuggling. Three film crew members accompanied a Syrian refugee boy from Greece to Sweden, while recording the journey in a documentary that was screened on Swedish public television in 2015. Despite widespread recognition, they were prosecuted and found guilty of human smuggling by all the levels of the Swedish judiciary. Using a variety of mat

Följande studie är en litteraturstudie, vars syfte har varit att undersöka kommunikationen med och stimuleringen av medvetslösa och dess effekter på patienten. Intresset var även att ta reda på hur mycket och i så fall vad patienter kommer ihåg från sin medvetslöshet. Metoden har varit att kritiskt granska, bearbeta och analysera 16 vetenskapliga artiklar från USA, Storbritannien, Irland och Kanad

Hjärtinfarkt är ett vanligt förekommande problem i dagens samhälle och kan drabba dem som utsätter sig för ett riskbeteende. Syftet med föreliggande litteraturstudie var att belysa patienters och anhörigas syn på information om rehabiliteringsfasen och regimföre-skrifter efter genomgången hjärtinfarkt. Genom analys av 10 vetenskapliga, engelskspråkiga artiklar framkom att det är en komplex sammans

Olycksfall bland barn är den största enskilda orsaken till dödsfall i den industrialiserade världen. I skolan och på vägen till och från skolan skadas många elever. Syftet med studien var att undersöka vilka uppfattningar och erfarenheter svenska och polska skolsköterskor har angående olycksfall och förebyggande av olycksfall bland grundskoleelever samt vilken roll skolsköterskorna har i det olyck