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Apalutamide in Patients With Metastatic Castration-Sensitive Prostate Cancer : Final Survival Analysis of the Randomized, Double-Blind, Phase III TITAN Study

PURPOSE: The first interim analysis of the phase III, randomized, placebo-controlled TITAN study showed that apalutamide significantly improved overall survival (OS) and radiographic progression-free survival in patients with metastatic castration-sensitive prostate cancer (mCSPC) receiving ongoing androgen deprivation therapy (ADT). Herein, we report final efficacy and safety results after unblin

Definition and sonographic reporting system for Cesarean scar pregnancy in early gestation : modified Delphi method

Objective: To develop a standardized sonographic evaluation and reporting system for Cesarean scar pregnancy (CSP) in the first trimester, for use by both general gynecology and expert clinics. Methods: A modified Delphi procedure was carried out, in which 28 international experts in obstetric and gynecological ultrasonography were invited to participate. Extensive experience in the use of ultraso

Results of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy after early failure of adjuvant systemic chemotherapy

BACKGROUND AND OBJECTIVES: Failure to respond to systemic chemotherapy is considered an exclusion criterion by some institutions for treatment with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC). However, it is unknown if these patients benefit from HIPEC treatment. This study aimed to report on outcomes of HIPEC in patients who failed to respond to adjuvant systemic c

Precision prognostics for cardiovascular disease in Type 2 diabetes : a systematic review and meta-analysis

BACKGROUND: Precision medicine has the potential to improve cardiovascular disease (CVD) risk prediction in individuals with Type 2 diabetes (T2D).METHODS: We conducted a systematic review and meta-analysis of longitudinal studies to identify potentially novel prognostic factors that may improve CVD risk prediction in T2D. Out of 9380 studies identified, 416 studies met inclusion criteria. Outcome

Transatlantic differences in the use and outcome of minimally invasive pancreatoduodenectomy : an international multi-registry analysis

BACKGROUND: Minimally invasive pancreatoduodenectomy (MIPD) has emerged as an alternative to open pancreatoduodenectomy (OPD). However, the extent of variation in the use and outcomes of MIPD in relation to OPD among countries is unclear as international studies using registry data are lacking. This study aimed to investigate the use, patient selection, and outcomes of MIPD and OPD in four transat

Identification of FasL as a crucial host factor driving COVID-19 pathology and lethality

The dysregulated immune response and inflammation resulting in severe COVID-19 are still incompletely understood. Having recently determined that aberrant death-ligand-induced cell death can cause lethal inflammation, we hypothesized that this process might also cause or contribute to inflammatory disease and lung failure following SARS-CoV-2 infection. To test this hypothesis, we developed a nove

09092016 679 56 mp67 swartling jerhre 2016

Parental Estimation of Their Child’s Increased Type 1 Diabetes Risk During the First 2 Years of Participation in an International Observational Study Journal of Empirical Research on Human Research Ethics 2016, Vol. 11(2) 106 –114 © The Author(s) 2016 Reprints and permissions: sagepub.com/journalsPermissions.nav DOI: 10.1177/1556264616648589 jre.sagepub.com Research Concerning Young People Type 1

https://www.teddy.lu.se/sites/teddy.lu.se/files/09092016_679_56_mp67_swartling_jerhre_2016.pdf - 2026-05-31

Mapping Resonance Structures in Transient Core-Ionized Atoms

The nature of transient electronic states created by photoabsorption critically determines the dynamics of the subsequently evolving system. Here, we investigate K-shell photoionized atomic neon by absorbing a second photon within the Auger-decay lifetime of 2.4 fs using the European XFEL, a unique high-repetition-rate, wavelength-tunable x-ray free-electron laser. By high-resolution electron spec

aromatashämmare – Vetenskap och Hälsa

aromatashämmare – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Etikett: aromatashämmare Rökning kan hämma vanlig behandling mot bröstcancer 2016-06-17 Det är känt att individer som röker tar stora hälsorisker. Nu visar dessutom en ny forskningsstudie vid Lunds universitet att en vanlig be

https://www.vetenskaphalsa.se/tag/aromatashammare/ - 2026-05-31

bråck – Vetenskap och Hälsa

bråck – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Etikett: bråck Teknikutveckling inom bråckkirurgin 2015-02-27 I Sverige opereras årligen runt 16 000 bråck i ljumskregionen på patienter över 15 år. Bråck i ljumskregionen kan vara lokaliserade ovan ljumskvecket (inguinala) eller nedom

https://www.vetenskaphalsa.se/tag/brack/ - 2026-05-31

Clostridium difficile – Vetenskap och Hälsa

Clostridium difficile – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Etikett: Clostridium difficile Fritt fram för diarrébakterier när tarmfloran slagits ut 2013-06-03 Syftet med antibiotika är att slå ut sjukdomsframkallande bakterier. Tyvärr går många oskyldiga bakterier under samtidigt

https://www.vetenskaphalsa.se/tag/clostridium-difficile/ - 2026-05-31

cytologiska analyser – Vetenskap och Hälsa

cytologiska analyser – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Etikett: cytologiska analyser Alternativa sätt för att diagnostisera svårdefinierade tumörer 2024-12-11 Cancersjukdomar som uppstår i mjukdels- och benvävnad utgör en stor och heterogen grupp av tumörer. Det finns över 10

https://www.vetenskaphalsa.se/tag/cytologiska-analyser/ - 2026-05-31