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Professor Contact details Email: ulf [dot] gerdtham [at] med [dot] lu [dot] se Phone: +46 46 222 48 10 Mobile: +46 76 887 12 04Organisation Health Economics Room number: alfa 4005, BMC E15 WebpageUlf Gerdthams profile in Lund University research portalPersonal website:https://sites.google.com/site/ulfgerdtam/Other affiliations Research team manager Health Economics Professor Department of Economic
https://www.lusem.lu.se/ulf-gerdtham - 2026-07-22
Background: In several European countries, centralization of oesophagogastric cancer surgery has been realized and clinical audits initiated. The present study was designed to evaluate differences in resection rates, outcomes and annual hospital volumes between these countries, and to analyse the relationship between hospital volume and outcomes. Methods: National data were obtained from cancer re
The effects of atmospheric aerosols are key uncertainties in climate models. One reason is the complex aerosol composition which includes a relatively large fraction of organics. Another reason is the small size of aerosols, which makes surface effects and processes important. These two factors make surface-active organics relevant for atmospheric aerosols, as they can affect crucial processes, su
We demonstrate that dissociative ionization of O(2) can be controlled by the relative delay between an attosecond pulse train (APT) and a copropagating infrared (IR) field. Our experiments reveal a dependence of both the branching ratios between a range of electronic states and the fragment angular distributions on the extreme ultraviolet (XUV) to IR time delay. The observations go beyond adiabati
The pattern of endocrine disorders in long-term survivors of childhood cancer has not been investigated comprehensively. Here, we aimed to assess the lifetime risk of these disorders in Nordic survivors of childhood cancer.
Codifications of human rights are widely understood as politically established instruments for evaluating human life. The call for such an apparatus emerges as a response to the age-old problem of social organization, constituting – in extension – a means by which to cope with the overall problem of survival. However, evaluating life is inherently problematic. It is problematic as it presupposes a
Routine imaging for diffuse large B-cell lymphoma (DLBCL) in first complete remission (CR) is controversial and plays a limited role in detecting relapse. This population-based study compared the survival of Danish and Swedish patients with DLBCL for whom traditions for routine imaging have been different.
ObjectiveWe undertook a 2-part, phase I, double-blind, placebo-controlled study to evaluate the safety and pharmacokinetics of multiple intravenous infusions of sirukumab, a human anti-interleukin-6 monoclonal antibody, in patients with cutaneous lupus erythematosus (CLE) or systemic lupus erythematosus (SLE). MethodsIn part A, patients with histologically confirmed CLE were randomized to 4 infusi
This paper presents an analysis on energy dissipation of digital half-band filters operating in the sub-threshold (sub-VT) region with throughput and supply voltage constraints. A 12-bit filter is implemented along with various unfolded structures, used to form a decimation filter chain. The designs are synthesized in a 65 nm low-leakage CMOS technology with various threshold voltages. A sub-VT en
Background Trials of imatinib have provided evidence of activity in adults with Philadelphia-chromosome-positive acute lymphoblastic leukaemia (ALL), but the drug's role when given with multidrug chemotherapy to children is unknown. This study assesses the safety and efficacy of oral imatinib in association with a Berlin-Frankfurt-Munster intensive chemotherapy regimen and allo geneic stem-cell tr
During the last five decades, survival of childhood cancer has increased from 25% to 80%. At the same time, however, it has become evident that survivors experience a broad range of therapy-related late adverse health effects. The aim of the Adult Life after Childhood Cancer in Scandinavia (ALiCCS) study is to investigate long-term health consequences of past and current therapies in order to impr
Buildings are responsible for over one-third of global energy use and greenhouse gas emissions, with heating and cooling being major contributors. Phase change materials (PCMs) offer a promising passive solution to improve thermal regulation and reduce heating and cooling loads. This review analyses different experimental and simulation-based studies on the integration of PCMs into building struct
INTRODUCTION: Postural orthostatic tachycardia syndrome (POTS) is a complex disorder with challenging diagnosis and management.METHODS: This cross-sectional, multi-national, web-based physician chart audit described clinical features and management of POTS, offering insights into disease burden and outcomes before and after the COVID-19 pandemic.RESULTS: Physicians (n = 153), primarily cardiologis
Researchers have widely applied discharge simulation using artificial neural networks (ANNs) and have gained prominence in water resources. Morphological features, watershed urbanization, and climate change influence hydrological variables. Thus, data-driven models need to be able to identify the hydrological relationships without explicitly stating the physical processes. The main objectives of t
The paper analyses the legal framework for the collection and distribution of remote sensing data, particularly in the field of sustainable development and environmental protection at the European level. The research firstly focuses on the historical evolution of space law at the international, European, and national levels, starting from the 1970s. In parallel, environmental law has rapidly devel
Human single-strand-selective monofunctional uracil DNA glycosylase 1 (hSMUG1) removes uracil, 5-hydroxymethyluracil (5hmU) and 5-fluorouracil (5FU) from DNA, thereby initiating the base excision repair (BER) process. hSMUG1 is important for maintaining genomic integrity and plays a significant role in cancer biology. Here, we present the structures of hSMUG1, including complexes with products (ur
Objectives: The vascular biology of restenosis is complex and not fully understood, thus explaining the lack of effective therapy for its prevention in clinical settings. The role of c-Myc in arteriotomy-induced stenosis, smooth muscle cell (SMC) differentiation and apoptosis was investigated in rat carotids applying full phosphorothioate antisense ( AS) oligonucleotides (ODNs). Methods: Carotid a
Measurements are presented of diffractive open charm production at HERA. The event topology is given by where the system X contains at least one charmed hadron and is well separated by a large rapidity gap from a leading low-mass proton remnant system Y. Two analysis techniques are used for the cross section measurements. In the first, the charm quark is tagged by the reconstruction of a D*±(2010)
1 The effectiveness of antimuscarinic agents in the treatment of the overactive bladder (OAB) syndrome is thought to arise through blockade of bladder muscarinic receptors located on detrusor smooth muscle cells, as well as on nondetrusor structures. 2 Muscarinic M-3 receptors are primarily responsible for detrusor contraction. Limited evidence exists to suggest that M-2 receptors may have a role
