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Human genes for the alpha and beta chains of complement C4b-binding protein are closely linked in a head-to-tail arrangement

C4b-binding protein (C4BP) is an important component in the regulation of the complement system and also binds the anticoagulant vitamin K-dependent protein S. These activities are performed by distinct, although structurally related, polypeptides of 70 kDa (alpha chain) and 45 kDa (beta chain), respectively. In this report we have investigated the genetic relationships between these polypeptides.

Kynurenine metabolites predict survival in pulmonary arterial hypertension : A role for IL-6/IL-6Rα

Activation of the kynurenine pathway (KP) has been reported in patients with pulmonary arterial hypertension (PAH) undergoing PAH therapy. We aimed to determine KP-metabolism in treatment-naïve PAH patients, investigate its prognostic values, evaluate the effect of PAH therapy on KP-metabolites and identify cytokines responsible for altered KP-metabolism. KP-metabolite levels were determined in pl

Genetic predisposition for Multiple Myeloma. Identification and functional characterization of risk variants

Multiple myeloma (MM) is a blood malignancy originating from plasma cells. First-degree relatives of patients with MM have two- to four-fold higher risk of MM. However, the molecular basis remains largely unknown. This Ph.D. project aims to identify novel DNA sequence variants predisposing to MM through genome-wide association studies (GWAS) and, subsequently, characterize identified variants func

Invasive Streptococcal Infection Can Lead to the Generation of Cross-Strain Opsonic Antibodies

The human pathogen Streptococcus pyogenes causes substantial morbidity and mortality. It is unclear if antibodies developed after infections with this pathogen are opsonic and if they are strain specific or more broadly protective. Here, we quantified the opsonic-antibody response following invasive S. pyogenes infection. Four patients with S. pyogenes bacteremia between 2018 and 2020 at Skåne Uni

High-sensitivity troponin I with or without ultra-sensitive copeptin for the instant rule-out of acute myocardial infarction

Background: The instant, single-sampling rule-out of acute myocardial infarction (AMI) is still an unmet clinical need. We aimed at testing and comparing diagnostic performance and prognostic value of two different single-sampling biomarker strategies for the instant rule-out of AMI. Methods: From the Biomarkers in Acute Cardiac Care (BACC) cohort, we recruited consecutive patients with acute ches

Safety Management Systems in micro and small air operators: mission possible?

This thesis explores the rationality, completeness and functioning of Safety Management Systems (SMS) amongst micro- and small-sized air operators in business aviation. In the absence of thorough literature in this sector of aviation, a survey of prior research on OHS(MS) and on non-aviation micro/small enterprises (MSE) provided a collection of factors contributing to their safety performance. Us

An operator theoretic approach to the Riemann Hypothesis

In 2023 an operator theoretic approach to the Prime Number Theorem was introduced by Olsen. In this thesis this approach is examined and applied to give a new, operator theoretic, proof of a different version of the Prime Number Theorem and of the Prime Number Theorem for arithmetic progressions. This approach is then expanded and rearranged to focus on the approximation error in the Prime Number

On Reconstruction of Cortical Functional Maps Using Subject-Specific Geometric and Connectome Eigenmodes

Understanding the interplay between human brain structure and function is crucial to discern neural dynamics. This study explores the relation between brain structure and macroscale functional activity using subject-specific structural connectome eigenmodes, complementing prior work that focused on group-level models and geometry. Leveraging data from the Human Connectome Project, we assess accura

Combinatorial DNMTs and EZH2 inhibition reprograms the H3K27me3 and DNAme-mediated onco-epigenome to suppress multiple myeloma proliferation

Comprehensive epigenomic studies in multiple myeloma (MM) that unravel the connections between major epigenetic regulators, their intertwined collaboration and the potential of combinatorial targeting remain limited. Utilizing ChIP-seq, ATAC-seq, RNA-seq, and DNA methylation (DNAme) data, we generated whole-genome chromatin annotations from normal plasma cells and MM patients, revealing epigenomic

The changing landscape of multimodality imaging in congenital heart disease : white paper

The congenital heart disease (CHD) population has seen substantial growth due to advancements in paediatric cardiac care, cardiothoracic surgery, anaesthesia, and intensive care. Although improved surgical interventions have enhanced survival rates for even the most severe defects, such as hypoplastic left heart syndrome, most CHD patients remain palliated rather than cured, requiring lifelong exp

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DIVISION OF STRUCTURAL MECHANICS Faculty of Engineering LTH, Lund University, Box 118, SE-221 00 Lund, Sweden • Tel: + 46 (0)46-222 73 70 • Fax: + 46 (0)46-222 44 20 • www.byggmek.lth.se xpTVSM-5271 (2024-01) MASTER’S DISSERTATION AT STRUCTURAL MECHANICS DEPARTMENT OF CONSTRUCTION SCIENCES | FACULTY OF ENGINEERING LTH | LUND UNIVERSITY BACKGROUND The increased adoption of cross-laminated timber (C

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/education/masterprojects/descriptions/TVSM5271_UT_Thaleb-Erik.pdf - 2026-05-21

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DIVISION OF STRUCTURAL MECHANICS Faculty of Engineering LTH, Lund University, Box 118, SE-221 00 Lund, Sweden • Tel: + 46 (0)46-222 73 70 • Fax: + 46 (0)46-222 44 20 • www.byggmek.lth.se xpTVSM-5245 (2020-01) MASTER’S DISSERTATION AT STRUCTURAL MECHANICS DEPARTMENT OF CONSTRUCTION SCIENCES | FACULTY OF ENGINEERING LTH | LUND UNIVERSITY CROSS LAMINATED TIMBER ELEMENTS WITH IRREGULAR GEOMETRIES AT O

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/education/masterprojects/descriptions/xp5245.pdf - 2026-05-21

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DIVISION OF STRUCTURAL MECHANICS Faculty of Engineering LTH, Lund University, Box 118, SE-221 00 Lund, Sweden • Tel: + 46 (0)46-222 73 70 • Fax: + 46 (0)46-222 44 20 • www.byggmek.lth.se xpTVSM-5219 (2016-06) MASTER’S DISSERTATION AT STRUCTURAL MECHANICS DEPARTMENT OF CONSTRUCTION SCIENCES | FACULTY OF ENGINEERING LTH | LUND UNIVERSITY HENRIK MALM PRESENTATION OCTOBER, 2016 REPORT Will be publishe

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/education/masterprojects/descriptions/xp5219.pdf - 2026-05-21

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DIVISION OF STRUCTURAL MECHANICS Faculty of Engineering LTH, Lund University, Box 118, SE-221 00 Lund, Sweden • Tel: + 46 (0)46-222 73 70 • Fax: + 46 (0)46-222 44 20 • www.byggmek.lth.se xpTVSM-5248 (2020-03) MASTER’S DISSERTATION AT STRUCTURAL MECHANICS DEPARTMENT OF CONSTRUCTION SCIENCES | FACULTY OF ENGINEERING LTH | LUND UNIVERSITY REFINED MODEL FOR CALCULATING THE DYNAMIC AMPLIFICATION FACTOR

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/education/masterprojects/descriptions/xp5248.pdf - 2026-05-21

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András Szigeti – October 2011 List of Publications and Papers Books, collections Concepts and the Social Order: Robert K. Merton and the Future of Sociology, editor, with Yehuda Elkana and György Lissauer. Budapest: Central European University Press, 2011. Religio Academici: Skepticism, Religion and the Pursuit of Knowledge, editor, with Péter Losonczi and Miklós Vassányi. Budapest: Akadémia

https://www.fil.lu.se/media/documents/persons/AndrasSzigeti/Szigeti_List_of_publications.pdf - 2026-05-04

När ljuset läker – Vetenskap och Hälsa

När ljuset läker – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök När ljuset läker 2017-11-07 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Medicinsk ljusbehandling av olika hudsjukdomar har använts sedan början av 1900-talet. Först mot infektioner som hudt

https://www.vetenskaphalsa.se/nar-ljuset-laker/ - 2026-05-18

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1 Karen Lahousse, Aspirant van het F.W.O.-Vlaanderen K.U. Leuven, Belgium Departement Lingustiek Blijde-Inkomststraat 21 B-3000 Leuven Karen.Lahousse@arts.kuleuven.ac.be Replacing expletive pro by verb movement in Romance languages ConSOLE, 8-10 December 2000 University of Lund, Sweden 0. INTRODUCTION This talk concerns expletive pro as it is alleged to appear in the subject position of sentences

https://konferens.ht.lu.se/fileadmin/user_upload/sol/ovrigt/konferens_console9_2000/Abstracts/Lahousse.pdf - 2026-05-18

TrotzkeBader_GLOW2013

TrotzkeBader_GLOW2013 1 Against usage-based approaches to recursion: The grammar-performance distinction in a biolinguistic perspective Andreas Trotzke (Konstanz) & Markus Bader (Frankfurt) Keywords: syntax; processing; recursion; center-embedding; third factor The distinction between grammar and performance distinguishes the biolinguistic approach to language from other cognitive accounts such as

https://konferens.ht.lu.se/fileadmin/user_upload/sol/ovrigt/konferens_glow36/Biolinguistics/Against_usage-based_approaches_to_recursion_-The_grammar-performance_distinction_in_a.pdf - 2026-05-18

Dålig kondition hos tioåring ökar risk för hjärtinfarkt längre fram – Vetenskap och Hälsa

Dålig kondition hos tioåring ökar risk för hjärtinfarkt längre fram – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Dålig kondition hos tioåring ökar risk för hjärtinfarkt längre fram 2011-10-27 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Foto: Flickr, z

https://www.vetenskaphalsa.se/dalig-kondition-hos-tioaring-okar-risk-for-hjartinfarkt-langre-fram/ - 2026-05-19