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Wilms' tumor gene 1 (WT1) is a zinc finger transcription factor that has been implicated as an oncogene in leukemia and several other malignancies. When investigating possible gene expression network partners of . WT1 in a large acute myeloid leukemia (AML) patient cohort, one of the genes with the highest correlation to . WT1 was quinolinate phosphoribosyltransferase (QPRT), a key enzyme in the .

The Greatwall kinase/Mastl is an essential gene that indirectly inhibits the phosphatase activity toward mitotic Cdk1 substrates. Here we show that although Mastl knockout (MastlNULL) MEFs enter mitosis, they progress through mitosis without completing cytokinesis despite the presence of misaligned chromosomes, which causes chromosome segregation defects. Furthermore, we uncover the requirement of

2023Knut and Alice Wallenberg Foundation has in cooperation with Åsa Petersén produced a short film about Huntington's disease and Petersén's research on HD.Link to the movie "Huntington's disease - the hunt for treatment" on YouTube (opens in a new window)The European Huntington Disease Network (EHDN) elected Åsa Petersén member of the executive committee. The EHDN is a nonprofit research network

https://www.huntington-research.lu.se/highlights - 2026-06-03

"Reduce, reuse, redesign: Lund University as a testbed for tackling the plastic crisis" (funded by Lund University Sustainability Fund, 2024–2025) was a hands-on project where we joined forces with Plastikfreie Stadt (Plastic-Free City) to identify solutions for limiting reliance on single-use plastics at Lund University. It was conducted in three steps:1. Existing practicesWe identified existing

https://www.plasticalternatives.lu.se/research/reduce-reuse-redesign - 2026-06-03

Unemployment and long-term unemployment is a recurring topic that is discussed in public debates. The recurring question is how society should solve this problem. But how and why is long-term unemployment considered a social problem? This essay aims to investigate two municipal labor market projects aimed at the long-term unemployed. The material was obtained from the City of Malmö's Labor and

OBJECT: Immortalized neural progenitor cells derived from embryonic rat hippocampus (HiB5), were transduced ex vivo with the gene for mouse nerve growth factor (NGF) to secrete NGF (NGF-HiB5) at 2 ng/hr/10(5) cells in culture. METHODS: Fifty-nine male Wistar rats weighing 300 to 370 g each were anesthetized with 60 mg/kg sodium pentobarbital and subjected to lateral fluid-percussion brain injury o

Background: Opioid overdose related injury or death can be prevented by bystander naloxone administration. For naloxone to be present when and where overdoses occur, opioid prevention education and naloxone distribution (OPEND) must be established on a broad level. This is the 30-month follow-up of the first multi-site naloxone project in Sweden, implemented at 31 sites in the County of Skåne 2018

17-18 June 2015  Centre for Languages and Literature  Lund University  Sweden Bridging Language Acquisition and Language Policy Keynote Abstracts (in order of presentation) Language Policy and Planning from a Complexity Theory Perspective Diane Larsen-Freeman In this talk, I adopt Complexity Theory (CT) as a transdisciplinary relational metatheory. A theory of language acquisition (or what I pr

https://konferens.ht.lu.se/fileadmin/_migrated/content_uploads/Keynote_Abstracts_01.pdf - 2026-05-30

Reflections from the second mobile research lab on food sharingAuthors: Yuliya  Voytenko Palgan, Vera Sadovska and Jennifer LyonsThe second mobile research lab on food sharing as part of the EU project CULTIVATE is now concluded. In October 2024, the IIIEE research team Yuliya Voytenko Palgan, Vera Sadovska, Oksana Mont and Andrius Plepys in the second mobile research lab on food sharing in Milan,

https://www.iiiee.lu.se/mobile-research-lab-food-sharing-milan - 2026-06-03

Uppsatsen fokuserar på några vuxnas erfarenheter av att lära sig svenska som andraspråk. Syftet är att undersöka hur vuxna inlärare upplever sin egen svenska idag, vilka faktorer de tillskriver sitt resultat och om de idag känner sig motiverade att fortsätta studera svenska. Metoden är kvalitativ i form av åtta halvstrukturerade intervjuer med kvinnliga informanter i åldrarna 35 till 49. De har bo

Kan en intelligent datormodell hjälp oss att skydda tjäderspelplatserna i de svenska skogslandskapen? Tjäderns mytomspunna spelplatser ligger dolda djupt inne i de vidsträckta svenska skogarna, och det är få som har förunnats att uppleva den fascinerande ritual som utspelar sig där varje vår. För att skydda dessa unika platser från mänsklig påverkan så finns det ett växande behov av att kunna lokaEffective methods for locating formally protected capercaillie (Tetrao urogallus) lek sites in the Swedish forest landscape are essential for targeted conservation measures. This study aimed to develop a multi-scale habitat suitability model for capercaillie lek sites in the northern Swedish forest counties, and further evaluate its potential to identify priority areas for future field survey effo

Metal ions are essential cofactors for precursor tRNA (ptRNA) processing by bacterial RNase P. The ribose 2'-OH at nucleotide (nt) –1 of ptRNAs is known to contribute to positioning of catalytic Me2+. To investigate the catalytic process, we used ptRNAs with single 2'-deoxy (2'-H), 2'-amino (2'-N), or 2'-fluoro (2'-F) modifications at the cleavage site (nt –1). 2' modifications had small (2.4–7.7-

Estrogen receptor a is expressed in the majority of breast cancers and promotes estrogen-dependent cancer progression. In our study, we identified the novel E3 ubiquitin ligase SHARPIN function to facilitate ERα signaling. SHARPIN is highly expressed in human breast cancer and correlates with ERα protein level by immunohistochemistry. SHARPIN expression level correlates with poor prognosis in ERα

https://www.vetenskaphalsa.se/tag/goodpastures-sjukdom/ - 2026-06-01

överlevare – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Etikett: överlevare Tre år efter intensivvård: Försämrad psykisk hälsa för covidpatienter 2025-12-17 Återhämtningen hos svårt sjuka patienter med covid-19 avtog tydligt efter det första året efter sjukdomen – både fysiskt och psyki

https://www.vetenskaphalsa.se/tag/overlevare/ - 2026-06-02

The identification of genetic causes for Mendelian disorders has been based on the collection of multi-incident families, linkage analysis, and sequencing of genes in candidate intervals. This study describes the application of next-generation sequencing technologies to a Swiss kindred presenting with autosomal-dominant, late-onset Parkinson disease (PD). The family has tremor-predominant dopa-res

Asparagine-linked glycosylation 13 homolog (ALG13) encodes a nonredundant, highly conserved, X-linked uridine diphosphate (UDP)-N-acetylglucosaminyltransferase required for the synthesis of lipid linked oligosaccharide precursor and proper N-linked glycosylation. De novo variants in ALG13 underlie a form of early infantile epileptic encephalopathy known as EIEE36, but given its essential role in g

Bakgrund: Bakgrunden till uppsatsen är de, i forskningen, uppmärksammade bristerna i att förutsäga studieframgång utifrån gymnasiala studieresultat. Forskning kring hur studenters sociala bakgrund påverkar studieframgång och fortsatta studieval, utgör också grund för uppsatsen. I centrum för uppsatsen står de betygsgrundande proven och de kunskaper som där efterfrågas. Syfte: Syftet med uppsatsen

Data Science Lab is part of Data Science Hub. The lab contains financial data terminals and is located on the first floor in LUSEM Learning Hub, room B:307, Alfa 5. It is open around the clock to all students at LUSEM. Data Science Lab and Financial databases In the lab you have access to financial data terminals. It is open for all students at LUSEM.Where: Room B:307, LUSEM Learning Hub, Alfa 5.

https://www.lusem.lu.se/organisation/lund-university-school-economics-and-management-library/lusem-library/data-science-lab - 2026-06-03