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Factors governing the activity of lyophilised and immobilised lipase preparations in organic solvents

Active site titration and activity measurements were performed in hexane on lyophilised lipase preparations containing different amounts of phosphate buffer and lipase immobilised on porous polypropylene. Lyophilisation of Thermomyces lanuginosus lipase with large quantities of phosphate salts (200 mm) increased the specific activity fourfold, and the number of rapidly titratable active sites incr

Feedback regulation of polyamine biosynthesis: a characterization at the molecular level

Popular Abstract in Swedish Två av de viktigaste polyaminerna påträffades redan i slutet av 1600-talet, som kristaller i tjursperma och har därför fått namnen spermin och spermidin. Dessa aminer bildas från en annan substans, putrescin, som först isolerades från ruttnande kött. Namnet putrescin kommer från engelskans putrefaction, som betyder förruttnelse. Polyaminer, som kemiskt sett är positivt The polyamines putrescine, spermidine and spermine are essential for cell growth and differentiation. The biosynthesis of polyamines are tightly regulated by feedback mechanisms involving two enzymes, namely ornithine decarboxylase (ODC) and S-adenosylmethionine decarboxylase (AdoMetDC). This thesis deals with the mechanisms behind the polyamine-mediated feedback control of these enzymes. The poly

MAGIC, SAFE and SMART model applications at integrated monitoring sites: Effects of emission reduction scenarios

Three well-known dynamic acidification models (MAGIC, SAFE, SMART) were applied to data sets from five Integrated Monitoring sites in Europe. The calibrated models were used in a policy-oriented framework to predict the long-term soil acidification of these background forest sites, given different scenarios of future deposition of S and N. Emphasis was put on deriving realistic site-specific scena

Management of saltpans as potential foraging sites for shorebirds

Abstract Estuaries and salt marshes are important wetlands used by waterbirds during winter and migration. However, many salt-marshes have been transformed into salinas, which currently function as high-tide roosts. Since traditional salt production is no longer profitable, many salinas have been abandoned or converted into aquaculture potentially becoming less attractive to waders. In this study

Structure-function relationships of hormone-sensitive lipase

Popular Abstract in Swedish Kroppens fettceller innehåller en energidepå i form av s.k. triglycerider, en glycerolmolekyl med tre påkopplade fettsyror, som kan användas vid behov (fasta, arbete och dylikt). För att kroppens andra celler ska kunna använda fettdepåerna som energikälla, måste fettsyrorna frikopplas från glycerolmolekylen och skickas ut ur fettcellerna till blodet. Fettsyrorna transpoThe primary role of hormone-sensitive lipase (HSL), an 84 kDa enzyme of 768 amino acids (in the rat protein), is to hydrolyse stored triacylglycerols in adipocytes of white adipose tissue. Catecholamines and insulin regulate lipolysis through cellular signalling. A major target of this regulation is HSL, activated through phosphorylation by cAMP-dependent protein kinase (cAMP-PK). Insulin activate

Ett läkemedels långa resa från labbet till apotekshyllan – Vetenskap och Hälsa

Ett läkemedels långa resa från labbet till apotekshyllan – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Ett läkemedels långa resa från labbet till apotekshyllan 2018-11-08 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Bild: istock.com/Eugene_Axe 15 års fo

https://www.vetenskaphalsa.se/ett-lakemedels-langa-resa-fran-labbet-till-apotekshyllan/ - 2026-05-18

Ett läkemedels långa resa från labbet till apotekshyllan – Vetenskap och Hälsa

Ett läkemedels långa resa från labbet till apotekshyllan – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Ett läkemedels långa resa från labbet till apotekshyllan 2018-11-08 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Bild: istock.com/Eugene_Axe 15 års fo

https://www.vetenskaphalsa.se/ett-lakemedels-langa-resa-fran-labbet-till-apotekshyllan-2/ - 2026-05-18

astma – Vetenskap och Hälsa

astma – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Etikett: astma Samband mellan mycket hög PFAS-exponering och astma hos barn 2026-04-22 Forskare vid Lunds universitet har undersökt samband mellan exponering för PFAS och utveckling av astma. Resultaten visar att bland de barn vars mamm

https://www.vetenskaphalsa.se/tag/astma/ - 2026-05-18

Distribution and dynamics of cell surface-associated cellCAM 105 in cultured rat hepatocytes

The cellular location of cellCAM 105 was studied by indirect immunofluorescence microscopy of primary rat hepatocytes grown in monolayer culture. Staining corresponding to cellCAM 105 was seen both in cell-cell contact areas and on the upper surfaces of the cells. In the cell-cell contact areas the antigen was not accessible to the antibodies unless the cells were either permeabilized with deterge

Complex Nature of the Genome in a Wine-spoilage Yeast, Dekkera bruxellensis.

When the genome organization of thirty native isolates belonging to a wine-spoilage yeast Dekkera/Brettanomyces bruxellensis, a distant relative of Saccharomyces cerevisiae, was examined, the number of chromosomes varied drastically, from 4 to at least 9. When single gene probes were used in Southern analysis, the corresponding genes usually mapped to at least two chromosomal bands, excluding a si

Effects of PEGylation on Membrane and Lipopolysaccharide Interactions of Host Defense Peptides

Effects of poly(ethylene glycol) (PEG) conjugation on peptide interactions with lipid membranes and lipopolysaccharide (LPS) were investigated for KYE28 (KYEITTIHNLFRKLTHRLFRRNFGYTLR), an antimicrobial and anti-inflammatory peptide derived from human heparin cofactor II. In particular, effects of PEG length and localization was investigated by ellipsometry, circular dichroism, nanoparticle trackin

Bacterial ferrochelatase turns human: Tyr13 determines the apparent metal specificity of Bacillus subtilis ferrochelatase.

Ferrochelatase catalyzes the insertion of Fe(2+) into protoporphyrin IX. The enzymatic product heme (protoheme IX) is a well-known cofactor in a wide range of proteins. The insertion of metal ions other than Fe(2+) occurs rarely in vivo, but all ferrochelatases that have been studied can insert Zn(2+) at a good rate in vitro. Co(2+), but not Cu(2+), is known to be a good substrate of the mammalian

Open Wounds? Trianon, the Holocaust and the Hungarian Trauma

The Trianon treaty has been a prominent site of memory in Hungarian historical culture from the day it was undersigned on 4 June 1920. 564,000 Hungarian Jews became victims of the Holocaust. In the first years after the end of World War II, the Holocaust was not a concept in Hungarian politics and historical culture. In the interwar period, in Hungarian historical culture the Trianon syndrome exhi

Hyperspectral and multispectral remote sensing for mapping grassland vegetation

Popular Abstract in English European dry extensive grasslands are biodiversity hotspots which are severely threatened by land use intensification and abandonment. In order to plan efficient conservation actions it is necessary to collect information on the current status of grasslands, their species diversity and prevailing environmental conditions. Remote sensing technology in combination with grAs a consequence of agricultural intensification, large areas of species-rich grasslands have been lost and farmland biodiversity has declined. Previous studies have shown that the continuity of grazing management can have a significant influence on the environmental conditions and the levels of plant species diversity in grassland habitats. The preservation of species-rich grasslands has become a

Stenens hus

Hunnebostrand var under 1900-talet ett av Sveriges främsta stenhuggerisamhällen. Här höggs och bearbetades stenen för att sedan fraktas till platser över hela världen. På 70-talet lades stenhuggeriverksamheten i Hunnebostrand ner, men spåren efter industrin lever kvar i samhället än idag. En viktig plats i Hunnebostrand under stenhuggeriepoken var Udden. Här höggs sten från Norra Högeberg och plaThis project examines the potential design of a visitor center named ”Stenens Hus” in Hunnebostrand, Sweden. The village was a prominent stone quarrying community in the 20th century, and the quarrying industry left its mark on the town even after it was shut down in the 1970s. One important place in Hunnebostrand during this era was Udden, where stone from Norra Högeberg was quarried. The site

Speedy A governs non-homologous XY chromosome desynapsis as a unique prerequisite for XY loop-axis organization

In mouse early pachytene spermatocytes, the X and Y chromosomes undergo rapid non-homologous (NH) synapsis and desynapsis, but the functional significance remains unknown. Here, we report that pachynema-specific knockout of Speedy A (SpdyA) from telomeres caused persistent Y-X NH synapsis, with the entire Y axis synapsed onto the X axis. This persistent Y-X NH synapsis did not interrupt meiotic se

Kvarteret Flaggskepparen, Industriellt byggande för offentligt ägda bostäder -En fallstudie i samarbete med NCC Komponent och MKB

The primary focus of this Master thesis is to study how industrial house building can be implemented during production of rental flats under the terms of public procurement. In order to determine a suitable working process as well as presenting a possible architectonic result of the process, a case study is carried through. A housing projekt is designed on a site i Malmö, where the commisioner is

An immunocytochemical study of the development of the olfactory system in the three-spined stickleback (Gasterosteus aculeatus L., Teleostei)

Antisera against a variety of substances have been found to produce an identical immunoreaction in the developing olfactory system of a teleost, the three-spined stickleback (Gasterosteus aculeatus). The label is localized in the olfactory placode, the olfactory nerve and those parts of the secondary olfactory tracts which constitute the dorsal descending fascicles and the ventral descending fiber

Instructions For External Experts Regarding Programme Evaluation At The Faculty Of Social Sciences 2

Instruction for external experts regarding programme evaluation at the Faculty of Social Sciences Page 1 of 7 Faculty Board DECISION Reg. No. STYR 2021/118 2021-02-04 Instruction for external experts regarding programme evaluation at the Faculty of Social Sciences This decision enters into force on 4 February 2021 and replace and invalidate the previous decision on Instructions for external expert

https://www.sam.lu.se/en/internal/sites/sam.lu.se.en.internal/files/2021-03/Instructions%20for%20external%20experts%20regarding%20programme%20evaluation%20at%20the%20Faculty%20of%20Social%20Sciences_2021.pdf - 2026-05-19