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Background: Color vision is enabled by visual opsins, a class of G-protein coupled receptors expressed in the eye. How well an organism discriminates color depends notably on the number of opsins, and their spectral sensitivity when bound to a light-sensitive chromophore (retinal). Spectral phenotypes have evolved convergently multiple times owing to opsin gene losses and duplications, both in ver

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En transaktion med en “warehousing”-struktur är en typ av två-stegstransaktion som omfattar flera moment, där säljaren först överlåter målbolaget till en tillfällig köpare som i sin tur överlåter målbolaget till en slutlig köpare. Den tillfälliga köparen används som ett lager för aktierna fram tills den slutliga transaktionen blivit godkänd av Europeiska kommissionen, varefter den slutliga transakA transaction with a warehousing structure is a type of two-step transaction, where the seller first transfers the target company to an interim buyer, who in turn transfers the target company to an ultimate buyer. The interim buyer is used as a ‘warehouse’ for the shares until the ultimate transaction is approved by the European Commission, after which the ultimate transaction can be implemented.

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It seems that people are more disconnected to the objects they own than ever before. What has changed in the last decades? People had tools and the skills to use them, but due to convenience and easy consumable entertainment, do-it-yourself was replaced by do-it-forme. Tasks we would have handled ourselves in the past are now done by a product or a service. This is disabling people. By losing ski

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Appraisal is assuredly one of the most important archival practices. The decision whether to preserve or destroy a collection of archival material, or parts thereof, has direct implications for multiple societal aspects, including the cultural heritage aspect, citizens’ ability to exercise their civil rights, and access to source material for legal and research purposes. Archival appraisal within

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The topic of this thesis is bioprocess control, more specifically control of industrial-scale microbial fed-batch bioprocesses. Its focus is therefore on methods which are easy to implement in an industrial setting, which gives certain limitations on sensors, actuators and control systems. The main part of the work in the thesis concerns control of the microbial substrate uptake rate by manipulat

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Solidariskt ansvar är huvudregeln när flera skadevållare gör sig skyldiga till en och samma skada. Solidariskt skadeståndsansvar innebär att skadelidande kan kräva en av skadevållarna på hela skadeståndsbeloppet som om skadevållaren skulle varit ensam ansvarig. Det krävs att de allmänna förutsättningarna för skadeståndsskyldighet är uppfyllda för var och en av skadevållarna. Den som har blivit kräJoint and several liability is the general rule in Swedish law when multiple guilty parties are responsible for one together caused damage. Joint and several liability means that the injured party can claim that just one of tortfeasors is held responsible for the entire amount of the damages like as if the tortfeasor was alone responsible for the whole damage. The general conditions for liability

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Popular science summary The effect of glucose and incretin proteins on insulin secretion and OPN production Insulin secretion is a sensitive cellular process with ramifications in diabetes mellitus development. Diabetes mellitus is characterized by hyperglycemia, a chronic condition defined by high levels of circulating glucose. Insulin hormone is the primary regulator of glucose absorption from

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FTRTIL is rapidly expanding on the Indian market after initiatives by the Indian government to increase the number of rolling trains. FTRTIL is today experiencing a greater demand for their products. Meanwhile are they also planning to expand their product range with new introductions. After trying to respond to the prevailing market demand for the E70 brake panel without any success made FTRTIL r

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Förevarande framställning syftar till att analysera skyddet för efterlevande make i relation till arvsrätten för den avlidnes släktarvingar, och i synnerhet dennes bröstarvingar. Utgångspunkten är Anna Christensens teori om de normativa grundmönstren. Arbetet behandlar rättsutvecklingen under 1900-talet och såväl det arvsrättsliga som det äktenskapsrättsliga regelverket diskuteras. Den svenska äThe aim of this thesis is to analyse the protection of the surviving spouse in relation to the right of the deceased's natural heirs’, in particular his or her legal heirs’. The starting point is Anna Christensen's Theory of Normative Patterns. The thesis deals with the legal development during the 20th century and both the Swedish law of succession and the marital legal framework are disc

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Super-Earths - planets with sizes between the Earth and Neptune - are found in tighter orbits than that of the Earth around more than one third of main sequence stars. It has been proposed that super-Earths are scaled-up terrestrial planets that also formed similarly, through mutual accretion of planetary embryos, but in discs much denser than the solar protoplanetary disc. We argue instead that t

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Background Osteoarthritis (OA) is highly prevalent in older adults and a growing cause of disability. Easily accessible first-line treatment of OA is increasingly important. Digital self-management programs have in recent years become available. Evidence of short-term effects of such programs are abundant, yet reports on long-term benefits and adherence to treatment are scarce. The current study’s

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Background: Metastatic breast cancer (MBC) is the main cause of breast cancer-related death. The outcome of MBC varies, and there is a lack of biomarkers to aid in prognostication. The primary aim of this study was to evaluate the prognostic value of gene expression (GEX) signatures in the primary tumor (PT) and distant metastasis (DM) for progression-free survival (PFS) and overall survival (OS).

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We present the first data release of VELOcities of CEpheids (VELOCE), dedicated to measuring the high-precision radial velocities (RVs) of Galactic classical Cepheids (henceforth, Cepheids). The first data release (VELOCE DR1) comprises 18 225 RV measurements of 258 bona fide classical Cepheids on both hemispheres collected mainly between 2010 and 2022, along with 1161 observations of 164 stars, m

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Background: Studies have shown that ambient air pollution is linked to preeclampsia (PE), possibly via generation of oxidative stress in the placenta. Telomere length and mitochondrial DNA copy number (mtDNAcn) are sensitive to oxidative stress damage.Objective: To study the association between prenatal exposure to ambient nitrogen oxides (NOx, a marker for traffic-related air pollution), and PE,

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Chemical pollution is identified as a significant driver of biodiversity loss, raising concerns about the effectiveness of current environmental risk assessment (ERA) practices. Conventional ERA approaches primarily rely on the endpoints of mortality, growth, and reproduction, often failing to capture the full scope of potential effects that chemicals can have on organisms. This is potentially pro

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Som ett led i de åtaganden som ställs på de länder som har undertecknat Kyotoprotokollet måste landvisa kolbudgetar fastställas. För att fastlägga bra kolbudgetar är det viktigt att kunna göra bra uppskattningar av kolmängden inom olika geografiska områden. Detta dels för att kunna uppskatta befintliga mängder och dels för att kunna påvisa förändringar över tiden. Denna studie hade som huvudmål atAs part of the undertakings of the Kyoto treaty, country-wise carbon balances must be brought forward. To do this, it is important to be able to make good estimations of the amount of carbon in forest areas. The reasons for this are to estimate the existing amounts as well as to prove changes over time. The main goal of this study was to estimate the amount of carbon stored in trees in a hundred-y

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Between 1980 and 2000, a number of Sub-Saharan African countries entered into conditional structural adjustment lending arrangements with the International Monetary Fund (IMF) in response to economic crisis and decline. Despite the fact that the crises had been due in part to long-term overdependence on primary sector activities, such as cash crop agriculture and natural resource extraction, many

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Background: Surgical extraction of testicular spermatozoa is needed in men with nonobstructive azoospermia (NOA) who wish to become biological fathers. Based on available uncontrolled studies with unspecific patient selection, microdissection testicular sperm extraction (mTESE), having a sperm retrieval rate (SRR) of 50%, is considered the most efficient sperm retrieval procedure. However, no rand

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There are four paths to a Swedish medical license. A shared agreement exists for those converting from a European license to recognize qualifications granted in the respective countries mutually. Swedish medical graduates and International Medical Graduates (IMGs) trained outside the EU/EES/Schweiz are assessed against the professional qualifications specified in the Higher Education Ordinance (19

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Background: Vasovagal syncope (VVS) is a common yet challenging condition with limited effective treatments. Elastic compression stockings (ECS) have been proposed as a potential therapy, but their real-world effectiveness remains unclear. Objectives: This study sought to compare the effectiveness of lower extremity compression with thigh-high ECS vs sham stockings for the prevention of VVS recurr