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Objectives: To identify sex-specific factors that may predict life expectancy after a diagnosis of Alzheimer’s disease (AD). Methods: The Swedish Alzheimer Treatment Study (SATS) is a prospective, observational, multicentre study in clinical practice that includes 1,021 participants (367 males and 654 females) diagnosed with mild-to-moderate AD at the start of cholinesterase inhibitor treatment (t
Popular Abstract in Swedish Parkinsons sjukdom är näst efter Alzheimers sjukdom den vanligaste neurodegenerativa sjukdomen. I Sverige finns ca 15.000-20.000 patienter med Parkinsons sjukdom. Symptomen beror på att en liten grupp nervceller som innehåller signalsubstansen dopamin, dopaminerga celler, gradvis dör av okänd anledning. Patienterna uppvisar muskelstelhet, darrningar och långsamma rörelsParkinson’s disease (PD) is the second most common neurodegenerative disorder and severely affects about one in a hundred persons over the age of fifty years. In PD, there is a reduced striatal concentration of the neurotransmittor dopamine, mainly caused by a degeneration of the dopaminergic neurons in the substantia nigra. Transplantation of embryonic dopamine neurons has been developed as an al
https://www.thm.lu.se/en/research-0/phd-projects - 2026-07-07
Popular Abstract in Swedish Hur dör neuron (hjärnceller) ? Det finns en mängd anledningar till varför neuron i hjärnan dör, olyckor med skallskador, neurodegenerativa sjukdomar såsom vid Parkinsons eller Alzheimers sjukdom eller efter förgiftningar. Den vanligast anledningen är dock stroke (slaganfall), dvs en akut förlust av blodförsörjningen till en del av hjärnan. Orsaken till stroke kan vara e
Many species of trees and shrubs thrive in Skåne's mild climate. Representatives of more than 200 genera are planted in the Botanical Garden. They are still arranged according to the founder Jacob Georg Agardh's plant classification from 1858. Some trees are more than 150 years old and were planted at the time when the garden was established. Examples are the tulip trees (Liriodendron) in the c
https://www.botan.lu.se/en/garden-and-plants/plants-outdoors/trees-and-shrubs - 2026-07-07
Short biographies of 104 lichenologists who have played a key role in the development of German lichenology are provided. These date from Hoffmann and the early days of lichen classification in the 18th century, through the 19th century with the discovery of the lichen symbiosis by Schwendener and Stahl, to the dynamic period of enormous scientific development of the 20th century. A significant bo
Metal music - A study about the genres of metal music, the culture and its place in school. The main purpose of this study is to investigate the cultural behavior and lifestyle of metal. It also gives an insight of Swedish music students' habit of listening and playing metal music. The area of this study is the music education of the upper secondary school. The background chapter consists of m
In April, 2019, the author discovered that Archbishop Erling Eidem’s sermons and speeches, since 1966/1978, have been kept in the University library of Uppsala. This has been overlooked by all authors earlier dealing with Eidem, only using shortened summaries. In Lützen, on November 6, 1942, Eidem stated that »our Gustavus-Adolphuscelebration may not be characterized by national self-sufficiency a
This book is the outcome of the International Symposium on Clause Linking in Semitic Languages, Kivik, Sweden, 5-7 August 2012. A strong incentive for the symposium was the renewed interest, in recent years, in the nature of non-main clause linking. Current research has brought into focus the concept of a main line and digressions from the main line in various discourse types. The conference invit
Stroke is one of the leading causes of death and disability, yet the cellular response to the ischemic insult is poorly understood limiting therapeutic options. Brain pericytes are crucial for maintaining blood-brain barrier (BBB) integrity and are known to be one of the first responders to ischemic stroke. The exact timeline of cellular events after stroke, however, remains elusive. Using the per
06-methylated guanine dinucleotides were used to study the influence of hydrogen bonding on the specific binding of the antitumor drug cDDP, cis-PtCl2(NH3)2, to DNA. In this interaction, the guanine-06 site appears to be important in explaining the preference for a pGpG-N7(1),N7(2) chelate, which results from H-bridge formation with the ammine ligand of cDDP. Guanine-06 methylated dinucleotides an06-methylated guanine dinucleotides were used to study the influence of hydrogen bonding on the specific binding of the antitumor drug cDDP, cis-PtCl2(NH3)2, to DNA. In this interaction, the guanine-06 site appears to be important in explaining the preference for a pGpG-N7(1),N7(2) chelate, which results from H-bridge formation with the ammine ligand of cDDP.Guanine-06 methylated dinucleotides and
C1q is the initiator of the classical complement pathway and opsonizes apoptotic cells to facilitate phagocytosis. Deficiency of C1q is the strongest known risk factor for development of systemic lupus erythematosus (SLE)a, which appears to be related to ensuing impaired clearance of apoptotic material. The objective of the current study was to investigate new ligands for C1q on the surface of apo
This thesis investigates how the progression of protagonist Esther Greenwood’s depression, told through her illness narrative, can be read to comprehend her outlook on her suicide plans and attempts, and psychiatric treatments she receives by her doctors Gordon and Nolan, in Sylvia Plath’s The Bell Jar (1963). Previous research has studied the doctors’ treatments’ effects on Esther, and the portra
Background. Excessive mortality and morbidity are serious problems after hip fracture in the elderly. Methods. Hip fractures in persons aged 50 years or older were prospectively registered in Japan in 2000. Questionnaires regarding both the first onset and the second 120-day period after hip fracture were obtained from 759 patients, 546 of whom were female and 213 male. Results. Their average age
Popular Abstract in Swedish Avhandlingen omfattar två delstudier. Huvudfokus är en fältstudie, där syftet är att förstå obotlig sjukdom och döden som konkreta erfarenheter på aktörsnivå. Med hjälp av observationer och intervjuer följs nio döende, anhöriga och sjuksköterskor under en tid i familjens hem. Den andra delstudien är en diskursanalys av danska socialpolitiska rapporter om det palliativa
