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Preclinical data suggest that chronic stress may cause cellular damage and mitochondrial dysfunction, potentially leading to the release of mitochondrial DNA (mtDNA) into the bloodstream. Major depressive disorder has been associated with an increased amount of mtDNA in leukocytes from saliva samples and blood; however, no previous studies have measured plasma levels of free-circulating mtDNA in a
Objectives: To assess whether partial meniscectomy is associated with increased risk of radiographic osteoarthritis (ROA) and worsening cartilage damage in the following year. Methods: We studied 355 knees from the Osteoarthritis Initiative that developed ROA (Kellgren-Lawrence grade ≥ 2), which were matched with control knees. The MR images were assessed using the semi-quantitative MOAKS system.
Background: Head and Neck Squamous Cell Carcinoma (HNSCC) tumors are often resistant to therapies. Therefore searching for predictive markers and new targets for treatment in clinically relevant in vitro tumor models is essential. Five HNSCC-derived cell lines were used to assess the effect of 3D culturing compared to 2D monolayers in terms of cell proliferation, response to anti-cancer therapy as
BACKGROUND: The method for red marrow dosimetry in radioimmunotherapy, in the absence of specific activity uptake in red marrow, is based on the activity measured in the blood or plasma. The activity concentration ratio of red marrow to blood is then assumed to be constant. The aim of the current study was to determine whether this ratio varies with time after injection. METHODS: Measurements were
Purpose. To examine whether the Sollerman hand function test is reliable in a test-retest situation in patients with chronic stroke. Method. Three independent examiners observed each patient at three experimental sessions; two days in week I (short-term test-retest) and one day in week 4 (long-term test-retest). A total of 24 patients with chronic stroke (mean age; 59.7 years, mean time since stro
We recently presented a new method for quantification of CArdiac FUnction - denoted CAFU - as the first step in the development of an automated method for integrated interpretation of gated myocardial perfusion single photon emission computed tomography (SPECT) images. The aim of this study was to validate CAFU in the assessment of global and regional function of the left ventricle. Quantitative g
The composition of the dominating population of freshly cut beef, and beef stored at 4 degrees C for 8 d, was studied by direct analysis of the 16S rRNA gene (PCR amplification, cloning and sequencing) and compared with pure culture technique where the isolates picked from the viable plate count were identified by sequencing of the 16S rRNA gene. The composition of the bacterial population was rec
BACKGROUND: Historically, intensive insulin therapy for type 1 diabetes (T1D) has improved glycemic control at the risk of adverse weight gain. The impact of continuous subcutaneous insulin infusion therapy (CSII) on weight in the current era remains unknown. We assessed changes in hemoglobin A1c (HbA1c) and weight in adults with T1D transitioning to CSII at 2 diabetes centers in Denmark and the U
Heteroclitic monoclonal antibodies are characterized by the ability to bind multiple epitopes with little or no similarity. Such antibodies have been reported earlier, but insight into to the molecular basis of this propensity is limited. Here we report that the KIM185 antibody to human CD18 reacts with the plasma protein C4b-binding protein (C4BP). This was revealed during affinity purification p
Background: Potato late blight caused by the oomycete pathogen Phytophthora infestans can lead to immense yield loss. We investigated the transcriptome of Solanum tubersoum (cv. Desiree) and characterized the secretome by quantitative proteomics after foliar application of the protective agent phosphite. We also studied the distribution of phosphite in planta after application and tested transgeni
Objective. Our aim was to investigate the protective effects of a Lipoxin A(4) analogue (LXA(4)) in the early phase of acute pancreatitis in rats. Materials and methods. Severe acute pancreatitis (SAP) was induced by injection of 5% sodium taurocholate into the pancreatic duct. Rats with SAP were treated with LXA(4) (0.1 mg/kg), 10 min after the 5% sodium taurocholate injection, after which LXA(4)
The thesis is a combination of both research fieldwork in sociology and documentary study on the historical development of Japanese animation (and manga) within China in the past two decades. The author tries to reveal some of the social changes taken place in Chinese society through a prevailing foreign culture that once did not even exist. The thesis examines the background, the initiation and d
Diarrhea-predominant irritable bowel syndrome (IBS-D) is a multifactorial disorder involving gut-brain axis dysregulation, altered barrier integrity, microbial imbalance, and stress-related mechanisms, with limited nutritional strategies targeting these pathways. Tannin-rich extracts may exert barrier-protective, microbiota-modulating, and stress-related effects. In a prospective before-after pilo
Inland surface waters are vital for the global carbon, energy, and water cycles; however, they are affected by climate change and human activities. Continuous monitoring of Water Surface Elevation (WSE) is essential for assessing water quantity and ensuring sustainable management. Traditional in-situ WSE measurements often face high costs and accessibility challenges. This study examines the use o
When grief finds new ways - a qualitative study about grief blogs The purpose of this study was to examine why people who suffer from grief chooses to share their experiences through blogs on the Internet. Furthermore and by studying the blogs we intended to gain understanding of the advantages and disadvantages that blogging can bring to the bloggers. The study is based on a qualitative analysis
The purpose of the existing methods for limiting the researcher’s bias is to see to that we have an objective and rational research. But what if there exist collective biases, and that the current process of falsification through peer to peer review only hinder individual ones. And this can happen because there is a shared fundamental belief system (FT) within the field, acquired through mutual ed
Denna studie har till syfte att undersöka hur rytmiken kan berika den kyrkliga verksamheten samt att kartlägga hur rytmikverksamheterna ser ut i fyra olika församlingar i Sverige. I teorikapitlet presenteras tidigare forskning och litteratur om Svenska Kyrkan som institution, musikens och dansens roll i kyrkan, rytmik, handlingsutrymme, samt Vygotskijs teorier om delaktighetens betydelse för barnsTitle: How can eurhythmics enrich the activities of Church of Sweden? A qualitative study of four pedagogues experiences, reflections and visions of Eurhythmics in the Church of Sweden. The purpose of this essay is to investigate how eurhythmics can enrich the activities in the work of the Church of Sweden and to study the eurhythmics activities in four different church communities. In the theory
In the European Union, innovation policies have called for boosting the innovative capacity of youth through education. Despite all efforts made towards this end, however, European economies still find youth innovation to be scarce. This scarcity exists in the region of Skåne too, and is evident in the increasing youth unemployment rates. The objective of this thesis is to shed a new light on this
Uppsatsens titel Seminariedatum Ämne/kurs Författare Handledare Nyckelord Syfte Metod Teoretiska perspektiv Empiri Resultat Sammanfattning Blankning – Finns det ett samband mellan blankning och nedgång i aktiekurser? 5 juni 2013 FEKH89 Examensarbete i finansiering på kandidatnivå, 15 HP Nathalie Erlandsson Funke, Marie Mohmand & Victoria Zetterberg Tore Eriksson Blankning, Aktielån, RegressionTitle Seminar date Course Authors Advisor Key words Purpose Methodology Theoretical perspectives Empirical Foundation Conclusions Abstract Short selling – Is there a relation between short selling and decrease in stock prices? 5 June 2013 FEKH89 Degree Project Undergraduate level, Business Admininstration, Undergraduate level, 15 University Credits Points (UPC or ECTS-cr Nathalie Erlandsson Funke,
Title: Are young nicotine addicts our future loyal customers? A qualitative study about marketing and increased consumption of white snus. Seminar date: 2020-06-03 Course name: FEKH29 - Bachelor Thesis in Marketing, 15 University Credit Points Authors: Johanna Arnborger, Ellinor Johannesson och Hedvig Spenner Crona Advisor: Oskar Christensson Keywords: White snus, marketing, nicotine addicti
