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As we know our population keeps growing and our cities are getting denser, urban sprawl is a phenomenon that affects a big part of our society. Research has shown that urban sprawl lacks consideration for human interactions and has an absence of proper urban planning. Multiple types of barriers have made it more and more difficult to create a sense of community within this environment. Moreover, d
This report analyses the technical opportunities for a complete decarbonisation of the basic material industry in Sweden by 2050. From this assessment, the report discusses policy implications for the industry sector given the overall framework set by the ongoing international climate negotiations. Relying on current production systems and applying “end-of-pipe” solutions will be insufficient to
Objectives. To study the correlation between Sunnybrook and House-Brackmann facial grading systems at different time points during the course of peripheral facial palsy. Study Design. Prospective multicenter trial. Setting. Seventeen otorhinolaryngological centers. Subjects and Methods. Data are part of the Scandinavian Bell's palsy study. The facial function of 1920 patients with peripheral facia
Physics-informed neural networks integrate physical laws into machine learning models to solve differential equations. This thesis investigates an inverse physics-informed neural network framework for estimating viscosity in Tetra Pak’s injection molding process, where direct measurements are not possible. By enforcing the Navier-Stokes equations and using sparse velocity and pressure data, a virt
Adaptation strategies can backfire and cause maladaptive outcomes, yet this is an understudied area in Swedish adaptation work, and a conceptually challenging theme with potential justice implications. The study explored the potential existence of maladaptation in Swedish municipalities in the Motala ström catchment area in collaboration with the FairWater research project, through conducting 18 q
This thesis investigates whether European industrial firms issuing green bonds enjoy a borrowing-cost advantage, so called a “greenium.” Using a sample of 1,305 euro-denominated issues from 2014 to mid-2025, we estimate fixed-effects OLS regressions of yield-to-maturity on a green-bond indicator, controlling for tenor, issuer size, leverage, interest coverage, credit rating, industry, issuer, and
We analyse the performance of risk reduction strategies for terrorist attacks with Improvised Explosive Devices (IEDs) for large governmental building structures in terms of cost-efficiency, significance and effectiveness accounting for life safety in conjunction with societal preferences and capabilities. The approach builds upon an extended Bayesian pre-posterior decision analysis and the princi
Background and purpose — Joint contracture is a common problem among children with cerebral palsy (CP). To prevent severe contracture and its effects on adjacent joints, it is crucial to identify children with a reduced range of motion (ROM) early. We examined whether significant hip, knee, or foot contracture occurs earliest in children with CP. Patients and methods — This was a longitudinal stud
Application of concurrent engineering (CE) to machinery has to consider the type of production (individual, serial), product complexity and level of design. Product development (PD) involves four characteristic levels of design that requires specific activities. The characteristic design levels require definitions of the activities for providing the necessary software and other support for all pha
Purpose: A cancer diagnosis and treatment pose significant physical and psychological challenges. The study aimed to explore factors associated with distress over time in women diagnosed with breast cancer undergoing radiotherapy (RT) with access to a digital information tool, specifically examining if factors such as health literacy and self-efficacy had any influence on distress. Methods: In thi
STUDY QUESTION Which spermatogonial differentiation states are present in prepubertal testes under normal conditions and following chemotherapy-induced depletion of spermatogonia in paediatric patients with cancer? SUMMARY ANSWER Single-cell transcriptomic analysis reveals that only undifferentiated spermatogonia are present in prepubertal boys, while differentiated states emerge during puberty, w
Degenerative meniscus lesions have been associated with both osteoarthritis etiology and its progression. We, therefore, sought to establish a human meniscus ex vivo model to study the meniscal response to cytokine treatment using a proteomics approach. Lateral menisci were obtained from five knee-healthy donors. The meniscal body was cut into vertical slices and further divided into an inner (ava
Literature and experience show that the differences between calculated and measured building energy performance still exist. The literature shows that user-related parameters are significant with regard to energy performance in low-energy buildings and this means that the choice of parameters is one of the main factors leading to this difference. However, the parameters themselves are associated w
Background: Recent studies in arrhythmogenic right ventricular cardiomyopathy (ARVC) patients have drawn attention to atrial fibrillation (AF) as an arrhythmic manifestation of ARVC and as an indicator of atrial involvement in the disease progression. We aimed to assess the prevalence of AF in the Scandinavian cohort of ARVC patients and to evaluate its association with disease clinical manifestat
Zinc is required for the regulation of proliferation, metabolism, and cell signaling. It is an intracellular second messenger, and the cellular level of ionic, mobile zinc is strictly controlled by zinc transporters. In mammals, zinc homeostasis is primarily regulated by ZIP and ZnT zinc transporters. The importance of these transporters is underscored by the list of diseases resulting from change
The European Union (EU) initiative on the Digital Transformation of Health and Care (Digicare) aims to provide the conditions necessary for building a secure, flexible, and decentralized digital health infrastructure. Creating a European Health Research and Innovation Cloud (HRIC) within this environment should enable data sharing and analysis for health research across the EU, in compliance with
BACKGROUND: Diarrhea is a leading cause of death among children <5 years of age and can have long-term adverse consequences for human development. The World Health Organization has recommended the therapeutic use of zinc for the treatment of diarrhea, along with oral rehydration solutions, since 2004. We studied recent trends in the use of zinc to treat diarrhea in 23 low- and middle-income countr
BACKGROUND: The cerebellar mutism syndrome (CMS) is one of the most disabling late effects after neurosurgery for a posterior fossa tumour in childhood. The reported incidences vary substantially in previous studies. AIMS: Pathophysiology is unknown, but damage to cerebello-thalamo-cerebral circuits is likely. The study focuses on the risk factors for development and severity of CMS including surg
Twenty years have passed since the Brundtland report launched the goal of “sustainable development” (SD). During these decades SD has become widely accepted and it is today established as a fundamental goal in most policy contexts at the international level as well in many countries, regions and cities. A growing research community focussing on various aspects of sustainable development has develo
