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ABSTRACTBackground: This study was designed to determine the effectiveness of a psychosocial intervention for family caregivers in delaying nursing home placement of individuals with dementia.Methods: The participants comprised 153 family caregivers of persons with dementia who underwent intervention and 155 family caregivers who did not. The intervention consisted of five weekly counselling sessi
The antiviral activities of type I IFNs have long been established. However, comparatively little is known of their role in defenses against nonviral pathogens. We examined here the effects of type I IFNs on host resistance against the model pathogenic yeast Cryptococcus neoformans. After intratracheal or i.v. challenge with this fungus, most mice lacking either the IFN-alpha/beta receptor (IFN-al
BACKGROUND: There is a wide range (5-50 per 100 000) in the reported annual incidence of acute pancreatitis. Furthermore, the predominant aetiology varies in different reports. This study was undertaken to establish the current incidence, aetiology and associated mortality rate in a defined population. METHODS: A retrospective study of all cases of acute pancreatitis admitted over a 10-year p
I TV-programmet »Uppdrag granskning« påstods nyligen (16 mars 2004) att det är livsviktigt för patienter med akut hjärtinfarkt att bo i närheten av rätt sjukhus. Frågan är när geografiska skillnader i dödlighet blir så pass stora och säkra att de har betydelse för den enskilda patienten. När man studerar skillnader i dödlighet mellan olika sjukhus bör man om möjligt också beakta landstingens roll.It is a known fact that the 1990s brought a decrease in mortality after myocardial infarction in Sweden but that differences in mortality rates following myocardial infarction still remain between the Swedish counties. Unresolved, however, are questions as to what these inter-county differences mean for the individual patient and what role hospital care plays in this context. We analysed all patie
Frontal eyes of crustaceans (previously Called nauplius eye and frontal organs) are usually simple eyes that send their axons to a medial brain Centre in the anterior margin of the protocerebrum. Investigations of a large number of recent species within all major groups of the Crustacea have disclosed four kinds of frontal eyes correlated with taxonomic groups and named after them as the malacostr
Background: The palliative care approach was originally developed for hospice care and for persons with cancer diseases, but has gradually expanded to embrace other contexts and people of all ages, with various life-threatening diseases. The palliative care concept thus also applies to older people and the context of municipal care, where Registered Nurses (RNs) hold key care provision positions.
Background: The prognostic role of the arterial blood gas tension of carbon dioxide (PaCO2) in severe Chronic Obstructive Pulmonary Disease (COPD) remains unknown. The aim of this study was to estimate the association between PaCO2 and mortality in oxygen-dependent COPD. Methods: National prospective study of patients starting long-term oxygen therapy (LTOT) for COPD in Sweden between October 1, 2
BACKGROUND: Ewing sarcoma is associated with a nonrandom pattern of primary and secondary chromosomal aberrations. Whereas the finding of rearrangements of chromosome 22, usually in the form of a balanced translocation t(11;22)(q24;q12), is important diagnostically, nothing is known about the potential prognostic impact of the secondary chromosomal aberrations. PROCEDURE: During a 1 3-year-period,
Objective Ventricular septal defects (VSDs), if haemodynamically important, are closed whereas small shunts are left without intervention. The long-term prognosis in congenital VSD is good but patients are still at risk for long-term complications. The aim of this study was to clarify the incidence of infective endocarditis (IE) in adults with VSD. Methods The Swedish registry for congenital heart
It is known that host cells can produce type I IFNs (IFN-alpha beta) after exposure to conserved bacterial products, but the functional consequences of such responses on the outcome of bacterial infections are incompletely understood. We show in this study that IFN-alpha beta signaling is crucial for host defenses against different bacteria, including group B streptococci (GBS), pneumococci, and E
Allogeneic transplantation after reduced intensity conditioning (allo-RIC) is a treatment option for patients with Hodgkin's lymphoma (HL) relapsing after autologous transplantation. In all, 23 adult patients with HL underwent allo-RIC in Sweden between 2000 and 2007. The median number of previous treatment lines was five and 20 patients (87%) were previously autografted. TRM at 100 days and at 1
Patients with antineutrophil cytoplasm antibody-associated vasculitis (AAV) requiring dialysis at diagnosis are at risk for developing end-stage renal disease (ESRD) or dying. Shortterm results of a trial comparing plasma exchange (PLEX) to intravenous methylprednisolone (IV MeP) suggested PLEX improved renal recovery. Here we conducted long-term follow-up to see if this trend persisted. A total o
Previous research has shown that most transitions into abstinence happens in the stages of the drug career quickly after the first treatment episode. Mortality is somewhat reduced for patients who become abstinent, but remains high for patients who remain addicted. However, even among substance abusers who become abstinent, mortality is often higher than in the general population. A consecutive sa
Brevmall Facul ty o f F ine and Performing Ar ts Public defence of theses and degree certificates in research studies This guide is designed to support the public defence process of doctoral students admitted under a special agreement on research studies at the Lund University Faculty of Fine and Performing Arts, and - doctoral students admitted to the national graduate school in the arts, Konstnä
Brevmall Facul ty o f F ine and Performing Ar ts Public defence of theses and degree certificates in research studies This guide is designed to support the public defence process of doctoral students admitted under a special agreement on research studies at the Lund University Faculty of Fine and Performing Arts, and - doctoral students admitted to the national graduate school in the arts, Konstnä
Brevmall Facul ty o f F ine and Performing Ar ts Public defence of theses and degree certificates in research studies This guide is designed to support the public defence process of doctoral students admitted under a special agreement on research studies at the Lund University Faculty of Fine and Performing Arts, and - doctoral students admitted to the national graduate school in the arts, Konstnä
Cerebellar growth is impeded following very preterm birth in human infants and the observed reduction in cerebellar volume is associated with neurodevelopmental impairment. Decreased levels of circulating insulin-like growth factor 1 (IGF-1) are associated with decreased cerebellar volume. The relationship between preterm birth, circulating IGF-1, and key cell populations supporting cerebellar pro
Dysentery, or rödsot, as the disease was previously known in Sweden, continues to be a major scourge in developing countries. However, the disease has almost disappeared in the West. Very different circumstances prevailed before infectious diseases declined as some of the major causes of death during the 19th century. In that era, 10,000 people could die of dysentery in a single year in Sweden. Th
BACKGROUND: Current global food systems threaten human health and environmental sustainability. In 2019, the EAT-Lancet Commission on healthy diets from sustainable food systems defined the first global reference diet to improve both areas, but there is no consensus on how to quantify the EAT-Lancet reference diet as a diet index and its relation to mortality has not been widely studied.OBJECTIVE:
INTRODUCTION: Insertion and use of central venous access devices (CVADs) can be associated with serious adverse events. The incidence is generally low but considering the vast use of CVADs the consequences can, from a patient safety and health economics perspective, be severe. No exact knowledge exists of number of catheters or complications in Sweden, as there is currently no comprehensive regist
