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Implementation of smooth interpolation for optimization

Models of physical systems are often expressed as a system of mathematical expressions derived from first principles. However some of the relationships present in a model are more conveniently expressed as a table, i.e. for certain values of independent variables the values of dependent variables are known. This imposes a limitation on the optimization software to be used, since optimization softw

The influence of external precipitating factors and peripheral neuropathy on the development and outcome of diabetic foot ulcers

The influence of external precipitating factors and the presence of peripheral neuropathy on the development and outcome of foot ulcers were evaluated in 314 consecutive diabetic patients. All patients were treated by the same foot care team. Each patient was represented by one ulcer, and primary healing was defined as intact skin for at least six months. External precipitating factors were identi

No evidence for a role of the catechol-O-methyltransferase pain sensitivity haplotypes in chronic widespread pain

Objectives The aim of this study was to investigate the association between the catechol-O-methyltransferase (COMT) 'pain sensitivity' haplotypes and chronic widespread pain (CWP) in two distinct cohorts. Methods Cases of CWP and controls free of pain were selected from two population-based studies: the Epidemiology of Functional Disorders study (EPIFUND) (UK) and the European Male Ageing Study (E

False Positive Responses in Standard Automated Perimetry

Purpose: To analyze the relationship between rates of false positive (FP) responses and standard automated perimetry results. Design: Prospective multicenter cross-sectional study. Methods: One hundred twenty-six patients with manifest or suspect glaucoma were tested with Swedish Interactive Thresholding Algorithm (SITA) Standard, SITA Fast, and SITA Faster at each of 2 visits. We calculated inter

Performance Improvement of a Phase Space Detection Algorithm for Electrocardiogram Wave Morphology Classification

An algorithm based on embedding phase space signal was developed by the authors in previous works. The algorithm detects the characteristic points of the waves of a multilead electroacardiogram (ECG). In the present work, the parameters of this algorithm are optimized to improve its performance. The algorithm uses 2 configurable parameters to obtain the phase spacethe dimension of the phase space

Amputation for vascular disease. Prognostic factors for healing, long-term outcome and costs.

Popular Abstract in Swedish I Sverige utförs cirka 3500 benamputationer varje år. Över 90% av alla amputationer görs på grund av kärlsjukdomar, där förträngningar i blodkärlen försämrar blodflödet med vävnadsdöd och vanligen kallbrand som följd. Det finns i huvudsak tre faktorer som ökar risken för amputation på grund av kärlsjukdom; ålder *80 år, rökning och diabetes. Om man inte tillhör någon avGeneral characteristics and outcome was evaluated in 177 consecutive patients who underwent a major amputation in a defined population. Smoking and diabetes lowered the mean amputation age. Healing failure at six months was seen in 24% of transtibial and in 11% of transfemoral amputees. Preoperative absence of gangrene and hemoglobin >120 g/L increased the risk of healing failure. Six months after

Storm damage and long-term mortality in a semi-natural, temperate deciduous forest

1. Wind-damaged trees, following the severe storm of 1999, are compared with data from a 50-year monitoring of Draved Forest, Denmark, to assess differing causes of mortality through time in an unmanaged semi-natural forest. Species-specific mortality characteristics and the changing effects of tree size and growth rate (diameter increment) on mortality through time are also investigated. 2. Storm

Efficacy and safety of outpatient treatment with direct oral anticoagulation in pulmonary embolism

Anticoagulant treatment of acute pulmonary embolism (PE) has traditionally been hospital-based. The lesser need for monitoring with the increasingly used direct acting oral anticoagulants (DOAC) in comparison to warfarin potentially facilitates outpatient treatment of PE with these drugs. This study aimed to evaluate efficacy and safety of outpatient treatment of PE with DOAC. We extracted data fr

CM-Score : A validated scoring system to predict CDKN2A germline mutations in melanoma families from Northern Europe

Background: Several factors have been reported that influence the probability of a germline CDKN2A mutation in a melanoma family. Our goal was to create a scoring system to estimate this probability, based on a set of clinical features present in the patient and his or her family. Methods: Five clinical features and their association with CDKN2A mutations were investigated in a training cohort of

Long-term effects of a preoperative smoking cessation programme

Introduction: Preoperative smoking intervention programmes reduce post‐operative complications in smokers. Little is known about the long‐term effect upon smoking cessation. Aim: To discover long‐term quit rates and the reasons behind successful cessation. Materials and Methods: 101 one of 120 smokers, randomised to smoking intervention or no intervention before hip and knee surgery, completed que

Generation of a conditionally null allele of the laminin alpha 1 gene

Laminins are heterotrimeric glycoproteins of the basement membranes. Laminin 1 (alpha 1, beta 1, gamma 1) is the major laminin expressed during early mouse embryogenesis. To gain access, to the physiological function of laminin alpha 1 chain, we developed a conditionally null allele of its encoding gene (Lama1) using the cre/loxP system. Floxed-allele-carrying mice (Lama1(flox/flox)) display no ov

Impact of the COVID-19 pandemic on sick leave among healthcare workers : a register-based observational study

Objectives To assess the impact of the COVID-19 pandemic on sick leave among healthcare workers (HCWs) in primary and specialist care and examine its causes. Methods Using individual-level register data, we studied monthly proportions of sick leave (all-cause and not related to SARS-CoV-2 infection) from 2017 to February 2022 for all HCWs in primary (N=60 973) and specialist care (N=34 978) in Nor

Low molecular weight heparin given the evening before surgery compared with conventional low-dose heparin in prevention of thrombosis

A prospective randomized double-blind trial was performed comparing conventional low-dose heparin with a low molecular weight heparin fragment for thromboprophylaxis in elective general abdominal surgical patients. The first dose of the heparin fragment was given the evening before surgery, and further doses were given thereafter every evening. There were 1002 analysable patients, 826 having recei

Sydtyrolsk separatism i kölvattnet av finanskrisen

Separatist movements are gaining ground around Europe. From south to north regional separatist movements are raising their voices. The goals of each unique movement vary, from calls for increased autonomy to demands for full independence. In Italy’s autonomous province South Tyrol the question of separatism is something that engages all of the ethnical South Tyrolean parties. The parties included

3D Shape Estimation Using Single Camera Setup and Laser Mesh Pattern

In biological observation of small flying animals, structured light methods can be used in order to make high frequency, no contact measurements in flight. Using a laser pointer that projects a 5625 point mesh pattern, as well as two high-speed cameras, three different methods for estimating the shape of 3D objects have been developed and evaluated. The cameras were calibrated, as well as the lase

Adaptive Decision Making Under Salience Effects

When people (repeatedly) choose among items characterized by multiple attributes ( price, quality, brand etc..) they often over-or under-weight certain attributes depending on which features stand out in the choice set. Salience theory explains how these distortions arise in a static setting. I extend the existing salience theoretic model for deterministic choice to a setting in which the decision

High-fat and low-fat fermented milk and cheese intake, proteomic signatures, and risk of all-cause and cause-specific mortality

PURPOSE: This study aimed to examine the associations between the intake of high- and low-fat fermented dairy (cheese and fermented milk), their proteomic profiles, and mortality risk.METHODS: This cohort study included 25,187 participants (mean age 57.7 years, 60.9% females). Fermented dairy intake was assessed by a modified diet history method. In a random subset of this cohort (n = 4359), we co

Syllabus qualitative methods 7.5 20171108

Brevmall Postal address Box 117, 221 00 LUND Visiting address Sandgatan 3, hus R Gamla Kirurgen Telephone switchboard +46 46 222 00 00 Fax +46 46 222 44 11 E-mail kansli@sam.lu.se Website www.sam.lu.se/en SAKA002, Qualitative Methods, 7.5 credits, third cycle The course was adopted by the Board of the Lund University Faculty of Social Sciences 6 February 2014 and the syllabus approved by the Board

https://www.sam.lu.se/en/internal/sites/sam.lu.se.en.internal/files/syllabus_qualitative_methods_7.5_20171108.pdf - 2026-06-23

Handbookforphdstudents

Handbook for PhD students FACULTY OF MEDICINE | LUND UNIVERSITY 04 06 10 Introduction Welcome PhD Studies at the Faculty of Medicine Aim of PhD Studies Rules and Regulations Organisation of PhD Studies at the Faculty of Medicine The Faculty The Faculty Board The Dean and Faculty Management Postgraduate Education Committee Departments/Head of Postgraduate Studies Postgraduate Studies office Contact

https://www.medicin.lu.se/sites/medicin.lu.se/files/handbookforphdstudents.pdf - 2026-06-23