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Objective: Lately, desmopressin (dDAVP) administered orally has been demonstrated to be an effective alternative in the management of nocturia in adults. Although the safety profile of dDAVP is well known, much of the experience originates from studies in enuretic children and younger adults, and it may not be readily extrapolated to elderly patients. In order to identify factors associated with a
Importance: Understanding the relationship between patients' clinical characteristics and outcomes is fundamental to medicine. When critically ill patients die after withdrawal of life-sustaining therapy (WLST), the inability to observe the potential for recovery with continued aggressive care could bias future clinical decisions and research. Objective: To quantify the frequency with which expert
Introduction: Perioperative dosing recommendations vary across Nordic haemophilia treatment centres (HTCs) for extended half-life (EHL) factor concentrates in haemophilia A/B (HA/HB) patients. Aim: To summarise Nordic real-world surgical experiences with EHL recombinant factor VIII/IX Fc (rFVIIIFc/rFIXFc) fusion proteins using retrospective data from clinical records at four HTCs in Finland, Swede
This study aims to identify the key leverage points of local tourism on Öland in which work can be initiated to bring about a more sustainable development of the tourism industry. To achieve this, an analysis was made of the tourism industry on Öland, and a methodological framework called The Öland Model developed for the initiation of a project to stimulate thinking among the actors on the island
Small-scale fisheries are highly important in terms of economic productivity and environmental relevance in Mexico’s Northwest. The Santa María Bay (SMB), in Sinaloa, México, is the largest bay in the state and is highly productive in terms of fishing and the economic activities derived from it. It is also home to endemic species and the region’s largest mangrove wetland. It faces environmental an
Thirty-nine streptococcal strains belonging to groups A, C, and G and 12 staphylococcal strains were investigated with respect to surface charge and hydrophobicity. Isoelectric points of the bacteria were determined by cross-partition experiments in dextran-polyethylene glycol two-phase systems containing charged polymers. The results obtained indicate that group A, C, and G streptococci have isoe
Type III protein S deficiency is characterized by a low plasma level of free protein S, whereas the total concentration of protein S is normal. In contrast, both free and total protein S levels are low in type I deficiency. To elucidate the molecular mechanism behind the selective deficiency of free protein S in type III deficiency, the relationship between the plasma concentrations of β-chain con
Objective: To assess available evidence on the use of end-points ( outcome measures) in clinical trials in systemic lupus erythematosus (SLE), as a part of the development of evidence-based recommendations for points to consider in clinical trials in SLE. Methods: The European League Against Rheumatism (EULAR) Task Force on SLE comprised 19 specialists, a clinical epidemiologist and a research fel
The ability to respond evolutionarily to increasing temperatures is important for survival of ectotherms in a changing climate. Recent studies suggest that upper thermal limits may be evolutionary constrained. We address this hypothesis in a laboratory evolution experiment, encompassing ecologically relevant thermal regimes. To examine the potential for species to respond to climate change, we exp
The measurement of the jet energy resolution is presented using data recorded with the ATLAS detector in proton-proton collisions at root s = 7 TeV. The sample corresponds to an integrated luminosity of 35 pb(-1). Jets are reconstructed from energy deposits measured by the calorimeters and calibrated using different jet calibration schemes. The jet energy resolution is measured with two different
Protein S functions as a cofactor for tissue factor pathway inhibitor (TFPI) and activated protein C (APC). The sex hormone binding globulin (SHBG)-like region of protein S, consisting of two laminin G-like domains (LG1 and LG2), contains the binding site for C4b-binding protein (C4BP) and TFPI. Furthermore, the LG-domains are essential for the TFPI-cofactor function and for expression of full APC
Results from a search for supersymmetry in events with four or more charged leptons (electrons, muons and taus) are presented. The analysis uses a data sample corresponding to 36.1 fb-1 of proton-proton collisions delivered by the Large Hadron Collider at s=13 TeV and recorded by the ATLAS detector. Four-lepton signal regions with up to two hadronically decaying taus are designed to target a range
We report the double-helicity asymmetry, ALLJ/ψ, in inclusive J/ψ production at forward rapidity as a function of transverse momentum pT and rapidity |y|. The data analyzed were taken during s=510 GeV longitudinally polarized p+p collisions at the Relativistic Heavy Ion Collider in the 2013 run using the PHENIX detector. At this collision energy, J/ψ particles are predominantly produced through gl
Dihadron and isolated direct photon-hadron angular correlations are measured in p+p collisions at s=510 GeV. Correlations of charged hadrons of 0.7
The PHENIX experiment at the Relativistic Heavy Ion Collider has measured φ meson production and its nuclear modification in asymmetric Cu+Au heavy-ion collisions at sNN=200 GeV at both forward Cu-going direction (1.2
We report measurements of the production of prompt D0, D+, D*+ and Ds + mesons in Pb–Pb collisions at the centre-of-mass energy per nucleon-nucleon pair sNN=5.02 TeV, in the centrality classes 0–10%, 30–50% and 60–80%. The D-meson production yields are measured at mid-rapidity (|y| < 0.5) as a function of transverse momentum (pT). The pT intervals covered in central collisions are: 1 < pT< 50 GeV/
Measurements of inclusive and direct photon production at midrapidity in pp collisions at s=2.76 and 8 TeV are presented by the ALICE experiment at the LHC. The results are reported in transverse momentum ranges of 0.47 GeV/c is at least one σ above unity and consistent with expectations from next-to-leading order pQCD calculations. © 2019 CERN.
