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Analysis of the molecular interplay between Streptococcus pyogenes and its human host

The common human pathogen Streptococcus pyogenes is the causative agent of numerous mild and severe clinical conditions. It expresses a number of secreted or cell wall-anchored proteins that modulate the human immune system and facilitate colonization and spread of the pathogen in the human host. During S. pyogenes infections, human plasma leaks into the site of infection as a consequence of infl

The IgG-degrading enzyme of Streptococcus pyogenes causes rapid clearance of anti-glomerular basement membrane antibodies in patients with refractory anti-glomerular basement membrane disease

In anti-glomerular basement membrane (anti-GBM) disease, IgG class autoantibodies induce rapidly progressive glomerulonephritis. Regrettably, many patients are diagnosed at a late stage when even intensive conventional treatment fails to restore renal function The endopeptidase IdeS (Immunoglobulin G degrading enzyme of Streptococcus pyogenes) (imliflidase) rapidly cleaves all human IgG subclasses

BspK, a serine protease from the predatory bacterium Bdellovibrio bacteriovorus with utility for analysis of therapeutic antibodies

The development of therapeutic and diagnostic antibodies is a rapidly growing field of research, being the fastest expanding group of products on the pharmaceutical market, and appropriate quality controls are crucial for their application. We have identified and characterized the serine protease termed BspK (Bdellovibrio serine protease K) from Bdellovibrio bacteriovorus and here show its activit

La rhétoriqueTx1011

La rhétoriqueTx1011 La rhétorique des transformations homogènes – ou l’argumentation fondée sur la structure de la réalité Göran Sonesson, Université de Lund Dans la sémiotique visuelle, le renouveau de la rhétorique, initié par le Groupe µ (1992), sans compter quelques initiatives timides et confuses dues a Barthes (1964), Durand, Cohen et d’autres (Bremond 1970), passe par ce que les anciens app

https://projekt.ht.lu.se/fileadmin/user_upload/sol/ovrigt/projekt_ccs/La_rhetoriqueTx.pdf - 2026-06-06