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A novel broad-spectrum elastase-like serine protease from the predatory bacterium bdellovibrio bacteriovorus facilitates elucidation of site-specific IgA glycosylation pattern

The increased interest in predatory bacteria due to their ability to kill antibiotic resistant bacteria has also highlighted their inherent plethora of hydrolytic enzymes, and their potential as natural sources of novel therapeutic agents and biotechnological tools. Here, we have identified and characterized a novel protease from the predatory bacterium Bdellovibrio bacteriovorus: BspE (Bdellovibr

Lagring och omvandling av energi

Sustainable energy storage and conversion utforskar innovativa metoder för att effektivt lagra och omvandla energi från olika förnybara källor. Fokus ligger på teknik som avancerade batterier, vätgasproduktion, bränsleceller och termokemiska system samt säkerhetsaspekter på batterilagringssystem. Forskningen syftar till att öka energitätheten, minska kostnaderna och förbättra skalbarheten, vilket

https://www.energy.lth.se/sv/forskning/lagring-och-omvandling-av-energi - 2026-05-05

The Role of Small-Bowel Capsule Endoscopy in the Diagnostic Algorithm of Complicated Perianal Disease

Introduction: Complicated perianal disease (cPD) may be the sole presentation of Crohn’s disease (CD). The role of small-bowel capsule endoscopy (SBCE) in the diagnostic algorithm of cPD is unclear. We aimed to evaluate the role of SBCE as a diagnostic tool, in patients with cPD, after a negative standard workup for CD. Methods: A multicenter, retrospective, cross-sectional study, in patients with

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Abstract in French Dans cet article j’aborderai, suite à ma thèse de doctorat, la problématique autour du récit en constellation en conversation exolingue. On appelle le récit en constellation le récit qu’un seul et même locuteur produit à plusieurs reprises en présence de locuteurs différents. Ce type de récit s’est avéré intéressant de plusieurs points de vue, notamment en ce qui concerne l’orig

A comparison of different orthogonal techniques for the investigation of the conformational stability of NIST mAb in liquid formulations

Antikroppar har ett brett användningsområde med stor potential men det är svårt att skapa stabila lösningar. Den strukturella stabiliteten är en viktig faktor när man väljer läkemedelskandidater, och i de tidiga utvecklingsstadierna görs prediktiva undersökningar för att ta reda på varje kandidats stabilitet och utvecklings-potential. Därmed är det av största intresse att utvärdera hur antikropparA great challenge during early development of medicinal antibodies is to determine the stability of the candidates. This is required to be able to select the candidates with the greatest developability. The stability of the candidates can be estimated using different orthogonal techniques and the aim of this investigation was thus to use orthogonal techniques for the investigation of conformationa

Fc epsilon RI levels and frequencies of peripheral blood dendritic cell populations in allergic rhinitis

The dendritic cell (DC) lineage encompasses a diverse population of cells with unique subtype-specific functions. In peripheral blood, four DC subsets have been identified based on their distinct expression of CD1c, CD141, CD16, and CD123, and these subpopulations exhibit functional properties in immune responses. However, their respective roles in allergic diseases, such as rhinitis, are unclear.

Demonstration of the non-identity between the Fc receptor for human IgG from group A streptococci type 15 and M protein, peptidoglycan and the group specific carbohydrate

After electrophoresis of an alkaline extract of type 15 group A streptococci, three main precipitation lines were obtained in diffusion experiments against commercial human polyclonal IgG (lines 1, 2 and 3). Nineteen of 23 sera (83%) from apparently healthy human individuals gave line 3, while 6 of them (26%) gave line 1. The sera giving line 1 did also give line 3. Line 2 was obtained with 2 sera