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Protein kinase C (PKC) plays a prominent role in immune signaling, and the paradigms for isoform selective signaling are beginning to be elucidated. Real-time microscopy was combined with molecular and biochemical approaches to demonstrate a role for PKC-epsilon in Fcgamma receptor (FcgammaR)-dependent phagocytosis. RAW 264.7 macrophages were transfected with GFP-conjugated PKC isoforms, and GFP m

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I den här uppsatsen undersöker jag hur översättning används som en feministisk skrivandestrategi i Nicole Brossards roman "Le desert mauve". Uppsatsen använder den franskkanadensiska teoretikern Susanne de Lotbinière-Harwoods idé om "traduction au féminin" - ett slags feministisk översättarpraktik, för att analysera de inslag av översättning som finns i romanen.

Celldöd, Lysosomer och Artificiell Intelligens

Understanding and therapeutic targeting of lysosome-dependent cell death 1. Deciphering the molecular machinery of lysosome-dependent cell death and its interactions with other cell death and survival processes 2. Understanding the role of lysosomes in diseases with altered cell death 3. Therapeutic modulation of lysosome-dependent cell death 4. Development of novel tools and methods for studyUnderstanding and therapeutic targeting of lysosome-dependent cell death 1. Deciphering the molecular machinery of lysosome-dependent cell death and its interactions with other cell death and survival processes 2. Understanding the role of lysosomes in diseases with altered cell death 3. Therapeutic modulation of lysosome-dependent cell death 4. Development of novel tools and methods for study

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The dendritic cell (DC) lineage encompasses a diverse population of cells with unique subtype-specific functions. In peripheral blood, four DC subsets have been identified based on their distinct expression of CD1c, CD141, CD16, and CD123, and these subpopulations exhibit functional properties in immune responses. However, their respective roles in allergic diseases, such as rhinitis, are unclear.