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Background and Aims: Although endovascular stent treatment is increasingly used in infrain-guinal atherosclerotic occlusive disease, outcome with focus on gender differences has not been reported in detail. Material and Methods: One hundred and twelve consecutive patients (67 [60%]) women, un-dergoing endovascular nitinol stent treatment of atherosclerotic lesions in the femoropopliteal segment
Mantle cell lymphoma (MCL) is characterized by the t(11;14)(q13;q32) and numerous copy number aberrations (CNAs). Recently, gene expression profiling defined a proliferation gene expression signature in MCL where high scores predict shorter survival. We investigated 31 MCL cases using high-density single nucleotide polymorphism arrays and correlated CNA patterns with the proliferation signature an
Galectin-3 is an adhesion/growth-regulatory protein with a modular design comprising an N-terminal tail (NT, residues 1-111) and the conserved carbohydrate recognition domain (CRD, residues 112-250). The chimera-type galectin interacts with both glycan and peptide motifs. Complete (13)C/(15)N-assignment of the human protein makes NMR-based analysis of its structure beyond the CRD possible. Using t
Background. Tissue transglutaminase (tTG) autoantibodies are serological markers for celiac disease. The aim was to study the efficacy of the pTnT-rhtTG plasmid and subsequent diagnostic accuracy of tTG autoantibodies for childhood celiac disease using radioligand binding assays. Methods. Coupled in vitro transcription and translation of tTG were performed by pTnT-rhtTG as well as by the pGEMt Eas
The glandular kallikrein family is composed of structurally related serine proteases. Studies show that the mouse family encompasses at least 14 highly conserved functional genes, but of these only the tissue kallikarein has a human ortholog. In man, the tissue kallikrein display high sequence similarity with prostate specific antigen and human glandular kallikrein 2, suggesting that they evolved
Glycosaminoglycan (GAG) chains anchored to core proteins form proteoglycans, widely distributed cell-surface macromolecules with multiple functions, such as regulation of growth factor and cytokine signaling, cell-cell interactions, and uptake of biomolecules. The biosynthesis of GAG can be manipulated by xylosides attached to various hydrophobic groups, and we have earlier reported that a naphtho
Abstract Title: Social services department’s modern centaurs – about social worker's dual role in cases of suspected crimes contribution Authors: Branislav Ros; Carl-Johan Martinsson Tutor: Lena Palvén Examiner: Elizabeth Martinell Barfoed The purpose of this study was to examine how social workers, in the social services department of economical aid, experience their dual role as helper
Popular science summary Identifying an African Paradise Flycatcher using molecular techniques Five species of Paradise Flycatchers (Terpsiphone) occur in mainland Africa. Colour polymorphism and hybridization in these birds make species identification and defining species boundaries challenging. A melanistic individual was captured in Gashaka-Gumti National Park in Nigeria, and could not be iden
The now Swedish province of Scania has had a long history of violence and unrest, with several wars being fought on Scanian soil. Such tumultuous times must have impacted the common people and their living conditions, yet bioarchaeological research is lacking for post-medieval Scania and much of Sweden. By analysing a skeletal material from a 16-18th century semi-urban cemetery in Ängelholm, for w
Helicobacter pylori is an important pathogen inhabiting the human stomach. H. pylori binds plasminogen, a 90 kDa glycoprotein secreted by liver cells, and utilizes it for enhancing virulence. Surface receptors on the bacteria recognize plasminogen that is then activated into plasmin by host factors. The active plasmin can degrade a range of host proteins including proteins of the extracellular mat
An estimated 6% of human greenhouse gas emissions are the result of enteric methane production by cows. Asparagopsis taxiformis, a semi-tropical alga, is one solution. Supplementation of this alga to cows at a small percentage of their daily intake has reduced methane emissions by over 98% in trials. This success has led to multiple commercialization attempts globally, although no Asparagopsis tax
Homework is widely used in most schools across the world to complement classroom teaching, increase knowledge retention, and foster good study habits. The research on the effect of homework assignment on student achievement is, however, inconclusive with earlier research indicating a positive relationship and newer studies giving a more nuanced picture. This thesis uses data from the 2019 wave of
The purpose of this study is to investigate how women with an ADHD diagnosis, who were diagnosed in the ages between 12-17, see their own experiences and identities in relation to role expectations of females. The ambition is to bring light to the stories of women, who have been in the shadow of the stereotypical ADHD man in society as well as in studies. The method chosen for empirical material i
Predictive archaeological modelling is a complex analytical process that requires the understanding of how complex environmental and anthropogenic spatial phenomena relate to the selection of archaeological site location and knowledge of the requirements and potential biases inherent in the method of modelling and the raw data itself. This paper aims to demonstrate the utility of the weights of ev
Mental illness has increasingly become a problem throughout the world and is believed to cost the global economy $16 trillion by 2030. Consequently, a growing body of literature investigates the possible causes of mental illness and more specifically, possible early life circumstances which may affect adult mental health. Limited research exists though in terms of exposure to recessions in utero a
Aims: Several studies have shown that self-rated health (SRH ) is associated with drug use. The aim of this study was to investigate the possible interaction between SRH and use of analgesics and hypnotics and its ability to predict disability pension. Methods: In 1974-78, complete birth-year cohorts of middle-aged male residents in Malmö, Sweden, were invited to a health screening, and the cohort
