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Difficult cannulation as defined by a prospective study of the Scandinavian Association for Digestive Endoscopy (SADE) in 907 ERCPs
Background. The definition of a "difficult" cannulation varies considerably in reports of endoscopic retrograde cholangiopancreatography (ERCP). Aims. To define a difficult cannulation, which translates into higher risk of post-ERCP pancreatitis. Patients and methods. Prospective consecutive recording of 907 cannulations in Scandinavian centers done by experienced endoscopists. Inclusion: indicati
Stability of PCR Targets for Monitoring Minimal Residual Disease in Neuroblastoma
In neuroblastoma (NB) patients, minimal residual disease (MRD) can be detected by real-time quantitative PCR (qPCR) using NB-specific target genes, such as PHOX2B and TH. However, it is unknown whether the mRNA levels of these targets vary either during treatment or at relapse. If marker genes are not stably expressed, estimation of MRD levels in bone marrow (BM) or peripheral blood will be hamper
Measurement of inelastic, single- and double-diffraction cross sections in proton-proton collisions at the LHC with ALICE
Measurements of cross sections of inelastic and diffractive processes in proton-proton collisions at LHC energies were carried out with the ALICE detector. The fractions of diffractive processes in inelastic collisions were determined from a study of gaps in charged particle pseudorapidity distributions: for single diffraction (diffractive mass M-X < 200 GeV/c(2)) sigma(SD)/sigma(INEL) = 0.21 +/-
TERT promoter mutations and telomere length in adult malignant gliomas and recurrences.
Use of Inhaled Corticosteroids in Patients With COPD and the Risk of TB and Influenza A Systematic Review and Meta-analysis of Randomized Controlled Trials
Background: The use of inhaled corticosteroids (ICSs) is associated with an increased risk of pneumonia in patients with COPD. However the risks of other respiratory infections such as TB and influenza remain unclear. Methods: Through a comprehensive literature search of MEDLINE EMBASE CINAHL Cochrane Library and ClinicalTrials.gov from inception to July 2013 we identified randomized controlled tr
Long-term molecular remissions in patients with indolent lymphoma treated with rituximab as a single agent or in combination with interferon alpha-2a: A randomized phase II study from the Nordic Lymphoma Group
The purpose of this phase II randomized trial was to evaluate the effect and safety of interferon-2a (IFN) in combination with extended dosing rituximab in patients with symptomatic, advanced indolent lymphoma responding to a standard single course of rituximab. Totally 123 patients were treated with rituximab 375mg/m2 once weekly for 4 weeks leading to 14 complete response (CR; 11%), 56 partial r
The growth of exocrine pancreatic insufficient young pigs fed an elemental diet is dependent on enteral pancreatin supplementation
Teenagers want to be told when a parent's death is near: A nationwide study of cancer-bereaved youths' opinions and experiences
Behaviour of Pine Sawflies in Relation to Pheromone-Based Pest Management
Popular Abstract in Swedish Hur man studerar kommunikation hos tallsteklar Totalt finns det cirka 125 beskrivna tallstekelarter i världen. De tillhör gruppen växtsteklar, och deras larver lever vanligen av tallbarr. Larvernas härjningar kan medföra att träden växer sämre eller rent av dör. Den färdiga stekeln äter inget, utan är helt inriktad på att para sig under sitt 10 –15 dagar korta liv i skPine sawflies (Hymenoptera: Diprionidae) are severe pine defoliators. This thesis investigated sawfly behaviour related to the use of pheromones in integrated pest management, including monitoring with pheromone traps and mating disruption. Neodiprion sertiferr females were placed on pine twigs in the field and 11–30 % of the females that remained on their twig after the first mating re-mated. Onl
Specificity and redundancy in the olfactory system of Ips typographus: Single-cell responses to ecologically relevant odors.
We screened 150 olfactory sensilla in single-sensillum recordings to unravel the mechanisms underlying host selection in the spruce bark beetle, Ips typographus (Coleoptera: Curculionidae: Scolytinae). Odor stimuli comprised of pheromone (various bark beetle spp.), host, and non-host compounds elicited strong and selective responses from 106 olfactory receptor neurons (ORNs), 45 of which were tune
Immobilization of thermostable beta-glucosidase variants on acrylic supports for biocatalytic processes in hot water
Two variants of the thermostable beta-glucosidase TnBgl1A (wt and N221S/P342L) from Thermotoga neapolitana were immobilized on acrylic supports (Eupergit (R) C, Eupergit (R) C250L, and cryogel) and evaluated at conditions close to the boiling point of water. Thermo-gravimetric analysis showed the supports to be stable <250 degrees C. Both wt and N221S/P342L were covalently bound to oxirane-groups
Human Leukocyte Antigen Matching in Heart Transplantation: Systematic Review and Meta-analysis.
Allocation of donors with regard to human leukocyte antigen (HLA) is controversial in heart transplantation. This paper is a systematic review and meta-analysis of the available evidence. PubMed, Embase, and the Cochrane Library were searched systematically for studies that addressed the effects of HLA matching on outcome after heart transplantation. Fifty-seven studies met the eligibility criteri
Acetabular dysplasia at the age of 1 year in children with neonatal instability of the hip.
Background and purpose As much as one-third of all total hip arthroplasties in patients younger than 60 years may be a consequence of developmental dysplasia of the hip (DDH). Screening and early treatment of neonatal instability of the hip (NIH) reduces the incidence of DDH. We examined the radiographic outcome at 1 year in children undergoing early treatment for NIH. Subjects and methods All chi
Health care costs attributable to overweight calculated in a standardized way for three European countries.
This article presents a tool to calculate health care costs attributable to overweight in a comparable and standardized way. The purpose is to describe the methodological principles of the tool and to put it into use by calculating and comparing the costs attributable to overweight for The Netherlands, Germany and Czech Republic. The tool uses a top-down and prevalence-based approach, consisting o
Accurate and precise zinc isotope ratio measurements in urban aerosols
We developed an analytical method and constrained procedural boundary conditions that enable accurate and precise Zn isotope ratio measurements in urban aerosols. We also demonstrate the potential of this new isotope system for air pollutant source tracing. The procedural blank is around 5 ng and significantly lower than published methods due to a tailored ion chromatographic separation. Accurate
The different strategies in treating displaced femoral neck fractures : mid-term surgical outcome in a register-based cohort of 1,283 patients aged 60-69 years
BACKGROUND AND PURPOSE: In patients around retirement age controversy exists as to whether to treat displaced femoral neck fracture (dFNF) with internal fixation (IF) or arthroplasty. An arthroplasty in this age group may need revision due to a long expected remaining lifetime. IF carries a higher risk of early failure but a maintained native hip if healing occurs. We aimed to determine the cumula
Impact of previous diverticulitis on 5-year survival and recurrence rates in patients with colorectal cancer
BACKGROUND: Diverticulitis and colorectal cancer (CRC) share epidemiological characteristics, but their relationship remains unknown. It is unclear if prognosis following CRC differ for patients with previous diverticulitis compared to those with sporadic cases and patients with inflammatory bowel disease or hereditary syndromes.AIM: The aim was to determine 5-year survival and recurrence after co
Hint of an exocomet transit in the CHEOPS light curve of HD 172555
HD 172555 is a young (∼20 Myr) A7V star surrounded by a 10 au wide debris disk suspected to be replenished partly by collisions between large planetesimals. Small evaporating transiting bodies, that is exocomets, have also been detected in this system by spectroscopy. After β Pictoris, this is another example of a system possibly witnessing a phase of the heavy bombardment of planetesimals. In suc
