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Objectives: To update the EULAR recommendations for management of knee osteoarthritis (OA) by an evidence based medicine and expert opinion approach. Methods: The literature search and guidelines were restricted to treatments for knee OA pertaining to clinical and/or radiological OA of any compartment of the knee. Papers for combined treatment of knee and other types of OA were excluded. Medline a
The study describes extraction of extracellular polymeric substances (EPS) from sewage sludge by applying enzymes and enzymes combined with sodium tripolyphosphate (STPP). Additionally, a systematic study of two non-enzymatic extraction agents is described. The assessment of the released products is made by colorimetrical methods and polysaccharides/glycoconjugates identification by the interactio
Blood coagulation factor IX is composed of discrete domains with an NH2-terminal vitamin K-dependent gamma-carboxyglutamic acid (Gla)-containing region, followed by two domains that are homologous with the epidermal growth factor (EGF) precursor and a COOH-terminal serine protease part. Calcium ions bind to the Gla-containing region and to the NH2-terminal EGF-like domain. To be able to determine
Retrograde and transganglionic labeling techniques are commonly used to visualize subsets of neurons and sensory afferent projections in the nervous system. These methods commonly require anesthesia and surgical methods. However, some tracers can also be administered systemically in awake animals, thus reducing risks associated with anesthesia and surgery and allowing for labeling of neuronal popu
Pituitary adenylate cyclase-activating polypeptide (PACAP) is an islet neuropeptide with potent insulinotropic action. The current study investigates PACAP expression in normal human and rat pancreatic islets, and whether it is altered in diabetic state. To that end, PACAP immunoreactivity was studied by immunofluorescence methods enhanced by the catalyzed reporter deposition (CARD) technique. Ins
Background and Aims: In a retrospective study using stereotactic body radiotherapy (SBRT) in medically inoperable patients with stage I NSCLC we previously reported a local control rate of 88% utilizing a median dose of 15 Gy x 3. This report records the toxicity encountered in a prospective phase II trial, and its relation to coexisting chronic obstructive pulmonary disease (COPD) and cardiovascu
Several authors have described how the formalization of recent decades has steered doctoral education towards structured curricula, more managerial control and new models for supervision. Largely absent from these accounts, however, is if and how doctoral education has been affected by the concurrent changes in research governance, in particular by the ‘projectification’ of research. For this stud
Microsoft Word - Rapport spänningsformlerOrtotropt080519 Master’s Dissertation Structural Mechanics PER JOHAN GUSTAFSSON STRESS EQUATIONS FOR 2D LAP JOINTS WITH A COMPLIANT ELASTIC BOND LAYER Denna sida skall vara tom! Copyright © 2008 by Structural Mechanics, LTH, Sweden. Printed by KFS i Lund AB, Lund, Sweden, May 2008. For information, address: Division of Structural Mechanics, LTH, Lund Univer
https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm7000/web7148.pdf - 2026-07-10
Efter aktiveringen av Internationella brottmålsdomstolens jurisdiktion över aggressionsbrottet i juli 2018 är dessa gärningar för första gången sedan Nürnbergtribunalen möjliga att väcka åtal för i en internationell domstol. Aggressionsbrottet kan bara begås av personer i position att effektivt utöva kontroll över eller styra politiska eller militära handlingar av en stat. Detta inkluderar, men inFollowing the activation of the International Criminal Court’s jurisdiction over the crime of aggression in July 2018, these acts are for the first time since the Nuremberg Tribunal possible to prosecute before an international court. The crime of aggression may only be conducted by persons in a position effectively to exercise control over or direct the political or military action of a State. Th
Nedmonteringen av rättsstatsprincipen i vissa av EU:s medlemsstater, vilket skett genom omfattande domstolsreformer som inkräktar på rättsväsendets oavhängighet, har resulterat i en ’Rule of Law’-kris som påverkar det unionsrättsliga samarbetet inom flera dimensioner. Respekt för rättsstaten är ett grundläggande krav vid anslutning till unionen enligt artikel 49 FEU och ett fundamentalt värde för The rule of law backsliding in some EU Member States through deficiencies in the judiciary has led to a crisis impacting several dimensions of the European cooperation. Respect for the rule of law is a fundamental value for the Union and thus a pre-condition for accession to the Union according to Article 49 TEU. Pursuant to Article 2 TEU the rule of law is a common value between the Member States
Five years into the present peacebuilding cycle in Colombia, violence is increasing again. In the Putumayo department, social-ecological conflicts between the state, armed groups and local communities persist. Social leaders, often representing local communities, are targets of violent actions and represent an extremely vulnerable group. In the Putumayo, at least 67 social leaders defending human
Det råder subjektivitet gällande vem som anses vara terrorist i konflikter, främst efter terroristattackerna i USA den 9 september 2001, där olika diskurser om försvar och terrorism existerar för att rättfärdiga våld och krig. Genom att anknyta en aktör till terrorism är det möjligt att beskriva sitt eget våld mot aktören som handlingar i självförsvar. Denna studies syfte är att synliggöra hur socThere is subjectivity in the matter of who is regarded a terrorist in conflicts, especially after the 9/11 2001 terrorist attacks in USA, by the use of discourses of defense and terrorism in order to legitimate violence and war. By linking a party to terrorism, it is possible to describe one’s violence against this party as acts in self-defense. This study’s purpose is to illustrate how social con
Despite Sweden having implemented strict laws against child abuse and adopting the Convention on the Rights of the Child into law, child abuse remains a significant societal issue. Although it is clear that legal changes play a role in strengthening the protection and rights of children, legislation and actual circumstances do not always align. This study aimed to highlight different experiences o
