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PurposeIn early breast cancer (BC), five conventional biomarkers—estrogen receptor (ER), progesterone receptor (PgR), human epidermal growth factor receptor 2 (HER2), Ki67, and Nottingham histologic grade (NHG)—are used to determine prognosis and treatment. We aimed to develop classifiers for these biomarkers that were based on tumor mRNA sequencing (RNA-seq), compare classification performance, a
A computational method has been developed to predict the turbulent Reynolds stresses and turbulent heat fluxes in ducts by different turbulence models. The turbulent Reynolds stresses and other turbulent flow quantities are predicted with a full Reynolds stress model (RSM). The turbulent heat fluxes are modelled by a SED concept, the GGDH and the WET methods. Two wall functions are used, one for t
Purpose - The purpose of this paper is to present numerical investigation of the gas/vapor bubble dynamics under the influence of an ultrasonic field to give a more comprehensive understanding of the phenomenon and present new results Design/methodology/approach - In order to formulate the mathematical model, a set of governing equations for the gas inside the bubble and the liquid surrounding it
Software-Defined Networking (SDN) is a novel architectural model for cloud network infrastructure, improving resource utilization, scalability and administration. SDN deployments increasingly rely on virtual switches executing on commodity operating systems with large code bases, which are prime targets for adversaries attacking the network infrastructure. We describe and implement TruSDN , a fr
As a contribution to the discussion on the relevance of the baroque concept in Swedish literary history, the article conducts a case study by testing the concept on the history of a specific genre: the Aesopic fable. The argument takes its starting point in the analysis of German fable history by the pioneering baroque scholar Wolfgang Kayser who asserted a lack of German fable writing during the
Contemporary ghost stories can be mediated through television series that familiarize viewers with the idea of supernatural/spiritual phenomena, and present a way of witnessing, experiencing and dealing with such phenomena. TheSwedish TV series Det Okända(The Unknown) is an example of such a production. A –presumably –spiritual phenomenon is tailored to fit a popular culture format and is served t
The article treats panorama scenes in the novels Father Goriot (1837–1843) by Honoré de Balzac and The Red Room (1879) by August Strindberg. My observations focus on the main characters Eugène de Rastignac and Arvid Falk, and the emotions that the capital arise in them where they stand in their high positions in front of Paris and Stockholm respectively; Rastignac on the hill of the Père Lachaise
Common commercial beans were cooked using two procedures: under pressure (autoclaving) and traditional cooking. Total starch extraction was higher in beans cooked with the traditional procedure (41.69-42.81%) than in the autoclaved samples (37.04-38.16%) and did not change during storage at 4°C. However, available and total resistant starch levels in vitro were not influenced by the cooking proced
Optical coherence tomography angiography (OCT-A) is a non-invasive, non-dye-based imaging modality that has the potential to enhance our understanding of retinal diseases. While this rapidly advancing imaging modality offers great potential, there is a need for community-wide understanding of the range of technologies and methods for interpreting the images, as well as a need to enhance understand
Peptide synthesis was carried out in a variety of organic solvents with low contents of water. The enzyme was deposited on the support material, celite, from an aqueous buffer solution. After evaporation of the water the biocatalyst was suspended in the reaction mixtures. The chymotrypsin-catalyzed reaction between Z-Phe-OMe and Leu-NH2 was used as a model reaction. Under the conditions used ([Z-P
We study the solvability for a system of pseudodifferential operators. We will assume that the systems is of principal type, i.e., the principal symbol vanishes of first order on the kernel, and that the eigenvalue close to zero has constant multiplicity. We prove that local solvability is to condition (PSI) on the eigenvalues as in the scalar case. This condition rules out any sign changes from -
