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I argue that Lisa Shapiro’s rational reconstruction of Descartes’s provisional moral code in terms of a broad conception of morality supplies us with an interpretative framework that make historiographical sense of the reception of Descartes’s moral philosophy in an Anglophone context on three occasions: the appeal to Descartes made by Henry More, Henry Sidgwick’s abrupt dismissal, and the ensuing

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Ad utrumque (paratus), latin for “prepared for both”, is the motto of Lund University. When the University was founded in 1666 its primary mission was to secure the southern provinces of Scania to the Swedish king. Scania had previously belonged to Denmark, but the peace settlement of 1658 made them part of Sweden. The seal of the university also shows the carolingian lion reading a book while hol

This paper is a part of a research project studying human interaction with lighting control devices in public indoor environments. Factors such as the perception of the environment or objects may guide human behavior, therefore the perception of lighting related objects may have an impact on the behavior toward energy saving. This paper reports the development of a questionnaire for measuring hu

BACKGROUND: Niemann-Pick disease type C (NP-C) is a rare neurovisceral disease characterised by progressive neurological degeneration, where the rate of neurological disease progression varies depending on age at neurological onset. We report longitudinal data on functional disease progression and safety observations in patients in the international NPC Registry who received continuous treatment w

We present a locus-specific protocol suitable for the investigation, from extracted DNA, into natural inter- and intra-specific genetic variation in a group of nine innate immune genes, all belonging to the β-defensin gene family. The products of these genes encode peptides with antimicrobial properties and form part of the innate immune system. The protocol amplifies the exon coding for the pepti

The epidermal growth factor receptor (EGFR) and the estrogen receptor (ER) modulator Amplified In Breast cancer-1 (AIB1) have been reported to be of importance for the prognosis of breast cancer patients. We have analyzed AIB1 and EGFR by immunohistochemistry in primary breast cancers (n = 297) arranged in a tissue microarray in order to predict outcome after adjuvant endocrine therapy with tamoxi

Background and purpose - Little is known about the comparative performance of patient-reported outcome measures in revision hip arthroplasty. We compared the performance of the WOMAC, the SF-36, the EQ-5D, and a pain-related visual analog scale (VAS) in revision hip arthroplasty. Methods - 45 patients with aseptic prosthetic loosening following primary hip arthroplasty completed the WOMAC, the SF-

It is debated whether cancer patients treated with chemotherapy can mount an adequate response to vaccination. Material and methods. Ninety-six adult outpatients with cancer, who were undergoing chemotherapy and/or monoclonal antibody, tyrosine kinase inhibitor, irradiation or corticosteroid treatments, were studied. Two doses of the pandemic influenza A(H1N1)/09 AS03-adjuvanted split virion vacci

One of the most important factors governing durability of concrete structures is reinforcement corrosion, and to prevent degradation associated with it, it is desirable to use large concrete covers. However, if the concrete cover is increased, the majority of design methods will predict that the crack widths at the concrete surface increase significantly. This can be contradictory, since the same

A search is reported for a neutral Higgs boson in the decay channel H -> Z gamma, Z -> l(+)l(-) (l = e, mu), using 4.5 fb(-1) of pp collisions at root s = 7 TeV and 20.3 fb(-1) of pp collisions at root s = 8 TeV, recorded by the ATLAS detector at the CERN Large Hadron Collider. The observed distribution of the invariant mass of the three final-state particles, m(ll gamma), is consistent with the S

Outcomes for patients with oesophago-gastric cancer are variable across Europe. The reasons for this variability are not clear. The aim of this study was to describe and analyse clinical pathways to understand differences in service provision for oesophageal and gastric cancer in the countries participating in the EURECCA Upper GI group.

IDO1 can be induced by interferon gamma (IFN-γ) in multiple cell types. We have earlier described that the DNA methyltransferase inhibitor zebularine also induces IDO1 in several rat cell clones. We now describe a synergistic induction of IDO1 expression by IFN-γ and zebularine. To elucidate the mechanism of the IDO1 induction we have studied the methylation status in the promoter region of the ID

OBJECTIVES:: To compare the plasma volume (PV) expanding effect of a fast infusion rate with that of a slow infusion rate of a fixed volume of 5% albumin, of the synthetic colloids, 6% hydroxyethyl starch 130/0.4 and 4% gelatin, and of 0.9% NaCl in a rat sepsis model and to compare the plasma-expanding effect among these fluids. DESIGN:: Prospective, randomized animal study. SETTING:: University h