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Early diagnosis of colorectal cancer (CRC) is crucial for successful treatment and mortality reduction. In this regard, blood-based tests play an indispensable role. Current research is focused on molecules actively secreted by tumor cells into small extracellular vesicles (EVs). This four-phase study included 613 CRC patients, 446 controls, and 120 precancerous lesions. High-throughput transcript

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A search for decays of the Higgs boson into a Z boson and a light resonance, with a mass of 0.5–3.5 GeV, is performed using the full 140 fb−1 dataset of 13 TeV proton–proton collisions recorded by the ATLAS detector during LHC Run 2. Leptonic decays of the Z boson and hadronic decays of the light resonance are considered. The resonance can be interpreted as a J/ψ or ηc meson, an axion-like particl

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A search for pair-production of vector-like leptons is presented, considering their decays into a third-generation Standard Model (SM) quark and a vector leptoquark (U1) as predicted by an ultraviolet-complete extension of the SM, referred to as the ‘4321’ model. Given the assumed decay of U1 into third-generation SM fermions, the final state can contain multiple τ-leptons and b-quarks. This searc

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Extractivism is a global phenomenon driven by the logic of capitalism that is manifested chiefly in mining, but also in agribusiness. Women around the world have emerged as leaders of resistance movements against extractivism. In this article, we question this recurrent theme in political ecology literature based on ethnographic fieldwork in southern Ecuador, where resistance has been less success

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BACKGROUND AND PURPOSE: Surgical outcomes in patients with flexible adult-acquired flatfoot deformity (AAFD) have not been evaluated in large prospective register studies. Calcaneal osteotomy and hindfoot arthrodesis are commonly used. We aimed to compare the results of these 2 procedures using preoperative and 1-year postoperative patient-reported outcome data from the Swedish Quality Register fo

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PET waste is the most visible environmental threat in the Maldives, a Small Island Developing State (SIDS). The thesis aims to propose the deposit refund system as a policy intervention, and evaluates the feasibility of introducing the system in the Maldives. In order to see how other SIDS have implemented the policy, the research uses policy evaluation framework to analyse the implementation mech

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Today, the concept of sustainability is central in several housing projects, not to mention the many other socio-technological projects for which the concept is a directive. In this study I problematize the relation of the paradigm of sustainable development to one of its main “pillars”, the social dimension, and how this can relate to the greatest challenge of our generation – climate change. As

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Bakgrund: Kvinnor som utsätts för våld i nära relation är ett globalt hälsoproblem. Våldet har ofta långvariga hälsokonsekvenser och påverkar även kvinnornas vardag negativt. I dagsläget saknas arbetsterapi samt arbetsterapeutisk forskning för denna målgrupp och det är idag oklart hur våldet påverkar aktiviteter i vardagen för våldsutsatta kvinnor. Syfte: Med stöd av Model of Human Occupation samm

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With Artificial Intelligence (AI) relying heavily on vast datasets, including publicly available personal online data and increasing amounts of fines for data breaches the individuals demand for control over personal data increases. The purpose of this thesis is to analyze the efficacy of the GDPR in granting data subjects control over their personal data when they are used to train AI. Therefore,

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This paper presents a measurement of the production cross-section of a Z boson in association with b- or c-jets, in proton–proton collisions at s=13 TeV with the ATLAS experiment at the Large Hadron Collider using data corresponding to an integrated luminosity of 140 fb-1. Inclusive and differential cross-sections are measured for events containing a Z boson decaying into electrons or muons and pr

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A search is presented for the pair production of heavy vectorlike quarks (VLQs) that each decay into a W boson and a light quark. This study focuses on events where one W boson decays into leptons and the other into hadrons. The search analyzed 140 fb−1 of pp collision data with pffiffi s ¼ 13 TeV, recorded by the ATLAS detector from 2015 to 2018 during run 2 of the Large Hadron Collider. The fina

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Capillary leak syndrome is a serious postoperative complication in neonates and infants after open-heart surgery for CHD. The aim of this study was to investigate the relationship between sternal opening width and the occurrence of capillary leak syndrome in patients undergoing cardiac surgery with delayed sternal closure.We retrospectively analysed the clinical data of neonates and infants (aged

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Introduction Ischaemia-reperfusion (I/R) injury remains a major challenge in heart transplantation, with mortality risk increasing significantly when allograft ischaemic time exceeds 4 hours. Non-ischaemic heart preservation (NIHP), using continuous hypothermic perfusion, has shown promise in preliminary studies for reducing I/R injury and improving outcomes. This randomised controlled trial aims

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Whether or not to allow socialisation between parents and children in out-of-home care presents a difficult ethical challenge for those social work professionals who need to make an assessment about what to do. In this as well as in other contexts, it is widely assumed that the principle of the best interest of the child (BIC) is both the legal and moral standard for decision-making for children.

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Outcomes for patients with oesophago-gastric cancer are variable across Europe. The reasons for this variability are not clear. The aim of this study was to describe and analyse clinical pathways to understand differences in service provision for oesophageal and gastric cancer in the countries participating in the EURECCA Upper GI group.