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A core outcome set for cranioplasty following stroke or traumatic brain injury - The COAST study

INTRODUCTION: There is substantial heterogeneity in the reporting of outcomes in the global cranioplasty literature. This study aimed to establish a core outcome set (COS) for cranioplasty after decompressive craniectomy for stroke or traumatic brain injury.METHODOLOGY: The scope was defined according to the criteria recommended by the Core Outcome Measures in Effectiveness Trials (COMET) Initiati

Common practice elements of cognitive behavioral therapy for gaming disorder : A systematic review and expert panel evaluation

Gaming disorder (GD) is an addictive disorder with health and social impacts recognized by the World Health Organization. Although the GD treatment evidence base appear to favor cognitive behavioral therapy (CBT), knowledge of its common practice elements is limited. This systematic review critically evaluates CBT interventions for GD, encompassing individual, group, and mixed approaches, to ident

Gene expression analysis of BCR/ABL1-dependent transcriptional response reveals enrichment for genes involved in negative feedback regulation.

Philadelphia (Ph) chromosome-positive leukemia is characterized by the BCR/ABL1 fusion protein that affects a wide range of signal transduction pathways. The knowledge about its downstream target genes is, however, still quite limited. To identify novel BCR/ABL1-regulated genes we used global gene expression profiling of several Ph-positive and Ph-negative cell lines treated with imatinib. Followi

Multiple Forms of Endocannabinoid and Endovanilloid Signaling Regulate the Tonic Control of GABA Release

UNLABELLED: Persistent CB1 cannabinoid receptor activity limits neurotransmitter release at various synapses throughout the brain. However, it is not fully understood how constitutively active CB1 receptors, tonic endocannabinoid signaling, and its regulation by multiple serine hydrolases contribute to the synapse-specific calibration of neurotransmitter release probability. To address this questi

Conflicting Climate Change Frames in a Global Field of Media Discourse

Reducing global emissions will require a global cosmopolitan culture built from detailed attention to conflicting national climate change frames (interpretations) in media discourse. The authors analyze the global field of media climate change discourse using 17 diverse cases and 131 frames. They find four main conflicting dimensions of difference: validity of climate science, scale of ecological

Protocolised reduction of non-resuscitation fluids versus usual care in patients with septic shock (REDUSE) : a protocol for a multicentre feasibility trial

INTRODUCTION: Administration of large volumes of fluids is associated with poor outcome in septic shock. Recent data suggest that non-resuscitation fluids are the major source of fluids in the intensive care unit (ICU) patients suffering from septic shock. The present trial is designed to test the hypothesis that a protocol targeting this source of fluids can reduce fluid administration compared w

Human Leucocyte Antigen, Infections and Systemic Inflammatory Biomarkers in Early Atherosclerosis in Children and Adolescents with Type 1 Diabetes

Background: This prospective study focuses on factors associated with arterial damage in children with type 1 diabetes (T1D). Materials and Methods: Eighty children and adolescents with T1D (mean age 15, range: 8-20 yrs; mean diabetes duration 7, range: 0.5 to 19 years) were investigated twice, approximately 2 years apart, for carotid artery intima-media thickness (cIMT) and compliance (CAC), flow

Global binding pattern of the Wilms' tumor gene 1 (WT1) +17AA -KTS isoform in leukemic cells

The aim of this study was to investigate the global DNA-binding pattern of Wilms' tumor gene 1 (WT1) in leukemic cells. Clinical and preclinical data indicate the zinc finger transcription factor WT1 as an oncogene, but the full target gene repertoire of WT1 in leukemic cells has not been previously characterized. The -KTS isoforms (excluding the three amino acid (KTS) insert between zinc finger t

RIFM fragrance ingredient safety assessment, hexyl hexanoate, CAS Registry Number 6378-65-0

The existing information supports the use of this material as described in this safety assessment. Hexyl hexanoate was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data from read-across analog hexyl isobutyrate (CAS # 2349-07-7) show that hexyl hexanoate is not

Transductive Image Segmentation : Self-training and Effect of Uncertainty Estimation

Semi-supervised learning (SSL) uses unlabeled data during training to learn better models. Previous studies on SSL for medical image segmentation focused mostly on improving model generalization to unseen data. In some applications, however, our primary interest is not generalization but to obtain optimal predictions on a specific unlabeled database that is fully available during model development

Hypothermia versus normothermia after out-of-hospital cardiac arrest

BACKGROUND Targeted temperature management is recommended for patients after cardiac arrest, but the supporting evidence is of low certainty. METHODS In an open-label trial with blinded assessment of outcomes, we randomly assigned 1900 adults with coma who had had an out-of-hospital cardiac arrest of presumed cardiac or unknown cause to undergo targeted hypothermia at 33°C, followed by controlled

Restricted cortical and amygdaloid removal of vesicular glutamate transporter 2 in preadolescent mice impacts dopaminergic activity and neuronal circuitry of higher brain function

A major challenge in neuroscience is to resolve the connection between gene functionality, neuronal circuits, and behavior. Most, if not all, neuronal circuits of the adult brain contain a glutamatergic component, the nature of which has been difficult to assess because of the vast cellular abundance of glutamate. In this study, we wanted to determine the role of a restricted subpopulation of glut

SAMPA Chip : The New 32 Channels ASIC for the ALICE TPC and MCH Upgrades

This paper presents the test results of the second prototype of SAMPA, the ASIC designed for the upgrade of read-out front end electronics of the ALICE Time Projection Chamber (TPC) and Muon Chamber (MCH). SAMPA is made in a 130 nm CMOS technology with 1.25 V nominal voltage supply and provides 32 channels, with selectable input polarity, and three possible combinations of shaping time and sensiti

Project Turnstone: Successful Collaboration and Collaboration Obstacles in Police, Border, and Coast Guard Cooperation

Projekt Turnstone är ett samverkansprojekt delvis finansierat av Europeiska kommissionen. Projektet är ett initiativ av Stockholmspolisens gränsbevakningsenhet. Samverkanspartners i projektet är Svenska Kustbevakningen, Region Nord öst; Helsingforspolisen; Gränsbevakningsväsendet, Finland; Polis och Gränsbevakningen i Estland; Statliga Gränsbevakningen, Lettiska republiken; och den Statliga GränssProject Turnstone is a collaborative project funded in part by the European Commission. The project is an initiative by the Stockholm Police. Collaborating partners in the project are the Swedish Coast Guard, Region Northeast; the Helsinki Police; the Gulf of Finland Coast Guard District; the Police and Border Guard Board in Estonia; the State Border Guard of the Republic of Latvia; and the State

Hotet från ovan. Konstfilmsinstitutionens inverkan på den svenska science fiction-filmen

Den svenska produktionen av Science fiction-film är för många okänd. Uppsatsen undersöker vilka svenska filmer som kan klassas som science fiction och hur den svenska konstfilmsinstitutionen inverkat på produktionen. Med utgångspunkt i svenska science fiction-entusiasters sammanställningar, analyseras innehållet kvantitaivt i de långfilmer som gjorts och graderas i en tregradig skala efter hur staThe production of Swedish science fiction is unknown for most people. The thesis studies which Swedish movies that can be classified as science fiction and how the Swedish art cinema institution has affected the production. The movies are analyzed and graded by how strong the science fiction influences are. The result eventuates in 29 Swedish science fiction movies, that strong influences are unco

Vbe johannes

SCIENCE AND PROVEN EXPERIENCE JOHANNES VETENSKAP OCH BEPRÖVAD ERFARENHET VID SBU | 1 2 | STEN ANTTILA & SUSANNA AXELSSON SCIENCE AND PROVEN EXPERIENCE JOHANNES ISBN 978-91-983575-5-4 © The VBE Research Program and the Authors Graphic design Johan Laserna Printed by Media-Tryck, Lund University, Lund 2018 Preface 9 NILS-ERIC SAHLIN A note on randomized controlled trials in evidence-based medicine 1

https://www.vbe.lu.se/sites/vbe.lu.se/files/vbe_johannes.pdf - 2026-05-30

Lönepolitiskt program I 2000 I

lönepolitiskt program för Lunds universitet Lönepolitiskt program för Lunds universitet fastställt av universitetsstyrelsen den 7 april 2000 Lönepolitiken har till grundläggande syfte att medverka till att universitetet kan nå sina mål. Motiverade, engagerade och kunniga medarbetare är förutsättningen för en hög kvalitet i universitetets verksamhet. Lunds universitet skall därför vara en arbets- p

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/lonepolitiskt-program-000407.pdf - 2026-05-30

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Fem år med OSA-föreskrifterna – erfarenheter från skyddsombud och anställda i Sacos förbund 5 år med OSA-föreskrifter – erfarenheter från skyddsombud och anställda i Sacos förbund Karin Fristedt © Saco 2021 www.saco.se Innehåll Sammanfattning 3 Inledning 4 Fokusgrupperna 5 Synpunkter på föreskrifter om organisatorisk och social arbetsmiljö 6 Hur fungerar OSA i arbetsmiljöarbetet – positivt och neg

https://www.saco.se/contentassets/046ecab27416417ca7ff2a6731e54213/2021_5-ar-med-osa.pdf - 2026-05-18