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These practice guidelines for the biological treatment of substance use disorders were developed by an international Task Force of the World Federation of Societies of Biological Psychiatry (WFSBP). The goal during the development of these guidelines was to review systematically all available evidence pertaining to the treatment of substance use disorders, and to reach a consensus on a series of p

In this case-control study, interview data on smoking habits were available for 179 de novo cases (116 with cytogenetic data) of acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS). Smoking habits were compared with a pooled set of population controls and hospital controls (diagnosed with malignant melanoma). Each pack-year of smoking increased the risk of MDS with 1.3% (95% CI 0.1-2.6

Neurogenesis in the subventricular zone (SVZ), which gives rise to new neurons in the olfactory bulb, continues throughout life but declines with increasing age. Little is known about how aging affects the intrinsic properties of the neural stem and progenitor cells (NSCs) in SVZ and the functional characteristics of their neuronal progeny. Here, we have compared the properties of NSCs isolated fr

Background. Tissue transglutaminase (tTG) autoantibodies are serological markers for celiac disease. The aim was to study the efficacy of the pTnT-rhtTG plasmid and subsequent diagnostic accuracy of tTG autoantibodies for childhood celiac disease using radioligand binding assays. Methods. Coupled in vitro transcription and translation of tTG were performed by pTnT-rhtTG as well as by the pGEMt Eas

Three commercially available, peptide-based enzyme-linked immunosorbent assay (ELISA) systems (Chlamydia trachomatis IgG and IgA EIA [CT-EIA; Labsystems OY, Helsinki, Finland], SeroCT IgG and IgA [SeroCT; Savyon Diagnostics Ltd., Ashdod, Israel], and Chlamydia trachomatis IgG and IgA pELISA [CT pELISA; Medac, Wedel, Germany]) were evaluated for the detection of serum immunoglobulin G (IgG) and IgA

The research explores the protections provided for migrant domestic workers who are highly undervalued and often exposed to trafficking, despite comprising an integral part of the labour force worldwide. Saudi Arabia is a focus destination country for the study, as it emerged from among the top destination countries absorbing 61 percent of recorded Ethiopian migrant domestic workers. Despite such

Sverige är ett av få länder som har tagit fram en nationell handlingsplan för att omsätta FN:s vägledande principer för företag och mänskliga rättigheter på nationell nivå. FN:s vägledande principer skapar inga nya folkrättsliga förpliktelser, utan uppmuntrar endast stater att ta fram nationella handlingsplaner för att omsätta principerna på nationell nivå. Sveriges framtagande av planen kan såled

Children has become an increasingly important target group for the Swedish cultural politics where museums play an important role. This focus on children has urged the museums to create different activities, such as exhibitions, specially modeled for the target group. This thesis studies the possibilities for learning in three exhibitions that in different ways have been adjusted for children and

Notwithstanding the increasing environmental awareness among consumers, researchers do not witness a substantial shift in consumption and disposal behaviour of textiles. Since research on disposal behaviour of home textile products is currently limited, it is relevant to explore consumers’ decision-making when handling no-longer-wanted home textiles. This thesis aims to better understand consumers

Payments for ecosystem services (PES), a mechanism of incentives or compensation to landowners for provision of ecosystem services, have grown as a tool for meeting conservation goals. The Costa Rican payments for ecosystem services (PSA) program is one of the best-known examples because of being one of the most established. Despite this, the PSA program and many other PES programs do not monitor

The energy intensive industry, producing basic materials, is responsible for 25 to 30% of today's global greenhouse gas emissions. The future supply of GHG neutral basic materials (e.g. steel, cement, aluminium, plastics, etc.) is a necessity for building a sustainable modern society. Deep decarbonisation of the energy intensive industries is technically possible but will require a major systemic

Background: Early diagnosis of mild lymphedema and treatment are important to prevent its progress. The tissue dielectric constant (TDC), measuring local tissue water in the skin and upper subcutis, has neither been related to the water displacement method (WDM) nor been used to diagnose mild arm lymphedema in patients at risk. Our aims were to evaluate TDC and WDM in combination with palpation, e

Background: Biochemical conversion of lignocellulosic biomass to simple sugars at commercial scale is hampered by the high cost of saccharifying enzymes. Lytic polysaccharide monooxygenases (LPMOs) may hold the key to overcome economic barriers. Recent studies have shown that controlled activation of LPMOs by a continuous H2O2 supply can boost saccharification yields, while overdosing H2O2 may lea

Detecting and forecasting riverine floods is of paramount importance for adequate disaster risk management and humanitarian response. However, this is challenging in data-scarce and ungauged river basins in developing countries. Satellite remote sensing data offers a cost-effective, low-maintenance alternative to the limited in-situ data when training, parametrizing and operating flood models. Uti

Background: The risk of sustaining a graft rupture after anterior cruciate ligament reconstruction (ACLR) is high. Contributing risk factors are, however, still not clearly identified. Objective: The aim of this systematic review was to identify and quantify risk factors for graft rupture after ACLR. Methods: A systematic review with meta-analysis (PROSPERO CRD42020140129) based on PRISMA guidelin

This article investigates the translation of Good Night Storiesfor Rebel Girls: 100 Tales of Extraordinary Women, a children’s bookwritten and published by Elena Favilli and Francesca Cavallo in 2016.Within the framework of Gideon Toury’s Descriptive Translation Studiesand Katharina Reiss’ text typology, the study focuses on the Swedish trans-lation Godnattsagor för rebelltjejer: 100 berättelser o

Objectives: To explore associations between carer burden and characteristics of (1) the informal carer, (2) the person with dementia, and (3) the care support network in 8 European countries. Design: Cross-sectional study. Setting: People with dementia judged at risk of admission to long-term care (LTC) facilities in 8 European countries (Estonia, Finland, France, Germany, Netherlands, Spain, Swed