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Predicting institutional long-term care admission in dementia: a mixed-methods study of informal caregivers' reports

AimTo investigate agreement between: (1) expected reasons and actual reasons for admission of people with dementia according to informal caregivers; (2) scores on measurement instruments prior to admission and the actual reasons for admission according to informal caregivers. BackgroundTimely admission of people with dementia is a crucial issue. Information is highly warranted on whether informal

Personalized Support with ‘Little’ Data

In this paper we look at opportunities to support the creation of value for all through the use of end-user-owned Virtual Personal Assistant. We use a chat-bot as example of technology with a possibility for transferring and diffusing new functionality, features and capabilities. This category of software can create potential value through its AI and natural language processing combined with emula

Drug Release and Skin Permeation from Lipid Liquid Crystalline Phases

We have studied drug release and skin permeation from several different liquid crystalline lipid formulations that may be used to control the respective release rates. We have studied the release and permeation through human skin of a water-soluble and amphiphilic drug, propranolol hydrochloride, from several formulations prepared with monoolein and phytantriol as permeation enhancers and controll

Group B streptococcal carriage in Sweden: a national study on risk factors for mother and infant colonisation

Background. To study group B streptococcus (GBS) colonisation in parturients and infants in relation to obstetric outcome and to define serotypes and antibiotic resistance in GBS isolates acquired. Methods. A population-based, national cohort of parturients and their infants was investigated. During 1 calendar week in 2005 all women giving birth (n=1,754) were requested to participate in the study

Chondroitin sulfate proteoglycans and microglia prevent migration and integration of grafted Muller stem cells into degenerating retina

At present, there are severe limitations to the successful migration and integration of stem cells transplanted into the degenerated retina to restore visual function. This study investigated the potential role of chondroitin sulfate proteoglycans (CSPGs) and microglia in the migration of human Muller glia with neural stem cell characteristics following subretinal injection into the Lister hooded

Thylakoids Promote Satiety in Healthy Humans. Metabolic Effects and Mechanisms

Thylakoids are the photosynthetic membranes of the chloroplasts in green leaves. Thylakoids have been found to promote satiety when added to food, both in animal experimental models and in human. The thylakoids act through inhibition of lipase-colipase catalysed hydrolysis of triacylglycerol, which is the main dietary fat component. The mechanism for inhibition is either a binding of thylakoids to

Normstödjande strukturer : Miljötematiken börjar slå rot i skolan

Popular Abstract in Swedish I december 1990 antog riksdagen i Sverige ett miljötillägg i skollagens s k portalparagraf: "Var och en som verkar inom skolan skall främja? respekt för vår gemensamma miljö." Alltså: Alla som verkar i skolan ska nu ta sig an den nya miljötematiken i samhället. Strax därefter tillsatte regeringen en ny läroplanskommitté med ett tydligt miljöuppdrag. I juni 1992, vid FNThis thesis explores the various influence processes that take place in connection with the dawn of a new theme - the environment - in today's society. Society has declared that schools, a place designed for the intentional influence of children and youths, shall utilise the new environmental theme in its practice. It focuses on the initiation process of the environmental theme in schools from the

Musikelever på gymnasiets estetiska program : En studie av elevernas bakgrund, studiegång och motivation

Tidigare forskning om motivation vid lärande har tenderat att fokusera på attributioner (de tolkningar elever och andra gör av orsaker till framgångar och misslyckanden) självuppfattning, målorientering och elevers autonomi. Denna avhandling syftar dels till att beskriva bakgrunden och skolgången för de elever som går på gymnasiets estetiska programs musikgren, dels till att mäta den motivation deIn previous studies research on motivation in education has tended to be focused on attribution (perceived causes of success and failure), self perception, goal orientation and autonomy. This thesis aims to describe the background and schooling of music students and to measure their motivation for music education. Motivation is viewed as a cognitive process, which influences learning through achie

Baseline IGF-I Levels Determine Insulin Secretion and Insulin Sensitivity during the First Year on Growth Hormone Therapy in Children Born Small for Gestational Age. Results from a North European Multicentre Study (NESGAS)

Objective: Developmental programming alters growth and metabolic outcome in children born small for gestational age (SGA). We explored insulin and glucose metabolism in SGA children treated with a fixed GH dose over 1 year. Methods: In the North European Small for Gestational Age Study (NESGAS), 110 short SGA children received GH at 67 mu g/kg/day for 1 year. Insulin secretion was assessed by acut

Mitochondrial DNA copy number is reduced in male combat veterans with PTSD.

Mitochondrial abnormalities may be involved in PTSD, although few studies have examined this. Mitochondrial DNA copy number (mtDNAcn) in blood cells is an emerging systemic index of mitochondrial biogenesis and function. The present study assessed mtDNAcn in male combat-exposed veterans with PTSD compared to those without PTSD as well as its correlation with clinical scales.

Reasons for Institutionalization of People With Dementia: Informal Caregiver Reports From 8 European Countries

Objectives: To explore reasons for institutionalization of people with dementia according to informal caregivers as well as variation in reasons between countries. Design: An explorative cross-sectional study was conducted in 8 European countries. Setting: Per country, a minimum of 3 long term care facilities, offering care and accommodation as a package, participated in this study. Participating

Comparing design processes for the BOP and TOP markets

The base (BOP) and the top (TOP) of the world income pyramid represent the poor people and the people from developed countries, respectively. About two-fifths of the world population can be categorized as poor. Poverty is a trap because children born to poor parents are likely to grow up to be poor adults. In recent years, a poverty reduction approach that combines business development with povert

Pharmacokinetic study of a systemically administered novel liposomal Temoporfin formulation in an animal tumor model

Meso-tetra(hydroxyphenyl)chlorin (mTHPC) (international generic name Temoporfin) is a potent photosensitizer used for photodynamic therapy (PDT). In this study the pharmacokinetics of a systemically administered novel lipid formulation of Temoporfin in a murine tumor model has been investigated. Fluorescence spectroscopy measurements were performed at several time intervals following drug administ

Momentum shearing interferometry of electron waves

We analyse recent experiments on momentum shearing interferometry of electron wave packets1,2 by using an optical analogy with shearing interferometry for optical waves. This analogy offers a convenient point of view to discuss the capabilities and difficulties of this technique used to access the phase of electron wave packets.

Rigorous characterization of time-resolved diffuse spectroscopy systems for measurements of absorption and scattering properties using solid phantoms

Two systems for measurements of absorption and scattering properties, based on picosecond-pulse lasers and single-photon counting detection, were characterized using a detailed protocol. The first system utilizes diode lasers at 660, 785, 910 and 974 nm as light sources. The second employs a Ti:sapphire and a mode-locked dye laser to produce tunable pulses in the range 610 - 1000 nm. Using solid t