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BACKGROUND: Chromosome 9p21 variants are associated with cardiovascular disease (CVD) but not with any of its known risk markers. However, recent studies have suggested that the risk associated with 9p21 variation is modified by a prudent dietary pattern and smoking. We tested if the increased risk of CVD by the 9p21 single nucleotide polymorphism rs4977574 is modified by intakes of vegetables, fr

Background: Exposure to airborne particles has a major impact on global health. The probability of these particles to deposit in the respiratory tract during breathing is essential for their toxic effects. Observations have shown that there is a substantial variability in deposition between subjects, not only due to respiratory diseases, but also among individuals with healthy lungs. The factors d

The tremendous increases in production of plastic materials has led to an accumulation of plastic pollution worldwide. Many studies have addressed the physical effects of large-sized plastics on organisms, whereas few have focused on plastic nanoparticles, despite their distinct chemical, physical and mechanical properties. Hence our understanding of their effects on ecosystem function, behaviour

Whereas existing business models for sustainability research have mainly focused on business model activities and sustainability outcomes for separate firms, we observe that alliances between small and large firms can influence a large firm's learning and dissemination of sustainable technologies, thereby contributing to the sustainable transformation of mass markets. According to the theoretical

Psychological stress is thought to be an important trigger of cardiovascular events, yet the involved pathways and mediators are largely unknown. Elevated systemic levels of the pro-inflammatory alarmin S100A8/A9 correlate with poor prognosis in coronary artery disease (CAD) patients. Here, we investigated the links between S100A8/A9 release and parameters of anti-inflammatory glucocorticoid secre

Human epidermal growth factor receptor 2 (HER2) status in breast cancer is routinely determined through immunohistochemistry (IHC) and/or in situ hybridisation (ISH) performed on whole tissue sections (WS). The purpose was to evaluate whether a gene protein assay (GPA) combining IHC with ISH, performed on breast cancer tissue microarray (TMA), is suitable for large-scale retrospective HER2 status

Large-scale science research facilities, such as those for investigation into the smallest components of physical matter, often consist of buildings with quite extraordinary features as regards shape and scale. These architectures are semiotically interesting in several ways: they have extraordinary outer forms that reflect the their inner activities; they require forms of mediation and planning t

Background: As tumors maintain an inflammatory microenvironment, anti-inflammatory medication can be useful in cancer therapy. We have previously shown an association with improved survival in melanoma for use of the H1-antihistamines desloratadine and loratadine, and here we examine use of H1-antihistamines and breast cancer mortality.Material and methods: We investigated use of the six major H1-

Enterprise Resource Planning (ERP) systems have been used by organizations and companies throughout the world since 1990. Many universities have recently replaced their legacy systems with ERP systems to improve work efficiency. One solution available for universities by way of management information system is the Campus ERP system. The Campus ERP system helps universities incorporate all departme

I juli 2016 introducerades lagen om tillfälliga begränsningar av möjligheten att få uppehållstillstånd i Sverige (den tillfälliga lagen). Ikraftträdandet av den tillfälliga lagen innebar att rätten till familjeåterförening för alternativt skyddsbehövande begränsades avsevärt. Enligt 7§ den tillfälliga lagen exkluderades alternativt skyddsbehövande från rätten att återförenas med sin familj under dIn July 2016, the Law on temporary limitations to the possibility of being granted residence permit in Sweden (the Temporary Law) came into force. The Temporary Law implied a sharp turn in Swedish asylum legislation. The right to family reunification, which previously had been granted subsidiary protection beneficiaries and refugees on a similar basis, was suddenly heavily restricted for beneficia

Åldrandet hos oss människor är individuellt och sker gradvis under en lång tid. Vissa funktioner i kroppen försämras och äldre människor har ofta av olika anledningar svårigheter att få i sig den mängd näring som de har ett behov utav, därför behöver de oftast dela upp sin kost i fler måltider fördelat under dagen. I denna uppsats jämförs kosten som serveras i ett ålderdomshem i en mindre kommun iThe aging of us humans is individual and occurs gradually over a long period of time. Some functions in the body deteriorate and older people often have difficulty for various reasons to get the amount of nutrition they need, so they usually need to divide their diet into more meals distributed during the day. In this essay, the diet served in a retirement home in a small municipality in northwest

Sverige är ett av få länder som har tagit fram en nationell handlingsplan för att omsätta FN:s vägledande principer för företag och mänskliga rättigheter på nationell nivå. FN:s vägledande principer skapar inga nya folkrättsliga förpliktelser, utan uppmuntrar endast stater att ta fram nationella handlingsplaner för att omsätta principerna på nationell nivå. Sveriges framtagande av planen kan såled

Kycklingkött är det kött med minst klimatpåverkan och fjäderfän, Gallus gallus, är den djurart som det föds upp flest av i världen. I Sverige ökar antalet fjäderfä samtidigt som den genomsnittliga besättningsstorleken ökar. Det är mer väsentligt än någonsin att hönsen som vi använder inom livsmedelsproduktionen mår bra och har en hög djurvälfärd. Synen är det sinnet som fåglarna använder mest och Factory produced chicken meat has the lowest climate impact and domesticated poultry, (Gallus gallus), is the world's most commonly bred animal. In Sweden the production of poultry is increasing, also the size of an average facility with chickens is increasing. Vision is their dominant sense organ and the vision is important for the animals to be able to explore their environment and search fo

Significant behavioral changes will need to be implemented to prevent the energy supply sector from tripling CO2 emissions by the midcentury. However, within the academic research, behavior changes remain primarily focused on the individual level, while the behavior of companies that are responsible for elevated greenhouse gas emissions falls behind. This master’s thesis analyses the core values