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Chemokines are important in the development and progression of tumors. We investigated the expression of CXCL14 and CXCL16 in colon cancer. Expression of mRNA was assessed in primary tumors and lymph nodes and CXCL16 mRNA levels were correlated to patient’s survival. Protein expression was investigated by two-color immunofluorescence and immunomorphometry. CXCL14 and CXCL16 mRNA levels and protein
Objectives: Guidelines recommend a single high-sensitivity cardiac troponin T (hs-cTnT) ≤14 ng/L measured ≥6 h after chest pain onset combined with a GRACE score <140 and the patient being pain-free for ruling out myocardial infarction (MI). There is however little data on the performance of this strategy. We therefore aimed to evaluate the diagnostic accuracy of a hs-cTnT ≤14 ng/L measured ≥6 h a
Increasing interdependencies between critical infrastructures have made these systems more effective, but also more susceptible to cascading failures. In order to reduce the likelihood and consequences of cascading failures, it is essential to develop tools that support incident commander decisions so that an initial failure does not spread to other infrastructures. Here, a framework for generatin
These guidelines are a consensus work of a considerable number of members of the immunology and flow cytometry community. They provide the theory and key practical aspects of flow cytometry enabling immunologists to avoid the common errors that often undermine immunological data. Notably, there are comprehensive sections of all major immune cell types with helpful Tables detailing phenotypes in mu
Background: Off-target [18F]flortaucipir (tau) PET binding in the choroid plexus causes spill-in into the nearby hippocampus, which may influence the correlation between [18F]flortaucipir binding and measures of cognition. Previously, we showed that partial volume correction (combination of Van Cittert iterative deconvolution and HYPR denoising; PVC HDH) and manually eroding the hippocampus result
BACKGROUND AND OBJECTIVE: Elderly patients are at high risk for medication errors in care transitions. The discharge summary aims to counteract drug-related problems due to insufficient information transfer in care transitions, hence the accuracy of its medication information is of utmost importance. The purpose of this study was to describe the medication discrepancy rate and associated risk fact
Symmetric solid electrolyte cells with La0.75Sr0.25Cr0.5Mn0.5O3-δ (LSCM)-Ce0.8Sm0.2O1.9 (SDC) composite electrodes are employed for nitric oxide (NO) removal. The LSCM powders are synthesized and the cells with LSCM-SDC composite electrodes are fabricated successfully. The results show that moderate SDC addition in LSCM electrode improves the cell performance due to the expansion of three phase bo
Mass-flowering crops provide forage for bees but also contain pesticides. Such pesticide exposure can harm bees, but our understanding of how this cost is balanced by forage benefits is limited. To provide insights into benefits and costs, we placed bumblebee colonies in 18 landscapes with conventional red clover fields treated with the neonicotinoid thiacloprid (flowers + pesticide), untreated or
Hepatic fibrosis can result as a pathological response to nonalcoholic steatohepatitis (NASH). Cirrhosis, the late stage of fibrosis, has been linked to poor survival and an increased risk of developing hepatocellular carcinoma, with limited treatment options available. Therefore, there is an unmet need for novel effective antifibrotic compounds. Cyclophilins are peptidyl-prolyl cis-trans isomeras
In order to calculate building energy usage, apart from the technical characteristics, user related factors needs to be determined. Unless the user related factors are determined by specific project, the idea is to apply a standardized list of input data for a normal operation during a normal year, so the calculated energy value does not depend on variation of these factors. Such list was issued b
First responders to cardiac arrest depend on cardiopulmonary resuscitation to keep patients alive. A new ventilation method, phase-controlled intermittent insufflation of oxygen, was previously shown to improve heart perfusion during cardiopulmonary resuscitation in a large-animal study, outperforming the best currently known ventilation method. This paper investigates whether the advantage of the
Solid state klystron modulators are typically based on oil-immersed pulse transformers due to their high performance, robustness, simplicity and straightforward design. However, the size of such transformers are highly impacted by pulse power, output voltage, pulse length, and required rise time; key parameters which are difficult to combine in long pulse high power linac applications. In this pap
Fredrik NG Andersson and Lars Jonung argue that the current push for fiscal activism is short-sighted. Instead, the Swedish case from the last 25 years shows that stable public finances combined with supply-side policies is the recipe for economic stability and growth.
Both Sweden and Finland have education systems promoting equity and equality. However, recent societal and political changes linked to increased immigration have created new challenges in efforts to support linguistic diversity. This paper aims to explore how multilingualism is represented in the national compulsory school curricula in the two contexts, using the language orientation framework: la
The PODMT3DMS-Tool, which consists of a proper orthogonal decomposition (POD) linked to the Modular Transport 3-Dimensional Multi Species (MT3DMS) code for nitrate simulation in groundwater, is introduced. POD, as a statistical technique, reduces a large amount of information produced by the MT3DMS model to provide the main components of the PODMT3DMS-Tool, i.e., space- and time-dependent terms of
Purpose: Buckets containing floating reed (Phragmites australis) simulated floating treatment wetlands (FTWs) and were used to improve the remediation performance of synthetic greywater (SGW). The aim of the study was to investigate the behaviour of FTWs for treatment of key contaminants within artificial greywater. Methods: Pelletized ochre based on acid mine water sludge was introduced to select
Migration influx in Western countries resulting in increasingly diverse societies results in more complex situations for bureaucrats in their client interactions in welfare organizations. The role of discretion for services to clients has received much attention in the public administration research and therefore this study explores the relation among perceived workload, anti-immigration attitudes
The clinical diagnosis of vascular dementia (VaD) is based on imaging criteria, and specific biochemical markers are not available. Here, we investigated the potential of cerebrospinal fluid (CSF) lipocalin 2 (LCN2), a secreted glycoprotein that has been suggested as mediating neuronal damage in vascular brain injuries. The study included four independent cohorts with a total n = 472 samples. LCN2
