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Objective - To screen risk groups for low bone mineral density by quantitative ultrasound in primary health care. Design - Cross-sectional. Intervention - None. Subjects - Risk categories for osteoporosis (a fragility fracture, malabsorption, immobilisation, inflammatory joint disease, glucocorticoid, fenantoin or thyroxin treatment, renal insufficiency or "miscellaneous"), 775 women and 179 men a
Treatment of prostatic carcinoma with estrogens is accompanied by an increased risk for thromboembolic and cardiovascular complications. The underlying mechanisms are still unknown. Patients treated with diethylstilbestrol (DES) were compared with patients given no estrogen treatment regarding factors (platelet aggregation in vitro and plasma lipoproteins) that have been suggested to contribute to
Risk preferences related to accidents or other situations involving the possibility of multiple fatalities were studied in 87 persons in Sweden belonging to two separate groups with professional or educational knowledge of risk- and crisis-management issues. Use was made of a tradeoff method, the results obtained consisting of von Neuman-Morgenstern utility functions over the range of 0-1000 fatal
Information and Communication Technologies (ICT) have relevant positive and negative impacts on environmental sustainability on various levels: First-order effects such as increasing electronic waste streams; second-order effects such as improved energy-efficiency of production; third-order effects such as a product-to-service shift in consumption or rebound effects in transport. In the simulation
Cytotoxic eosinophil granule proteins are considered important in the pathogenesis of allergic airway diseases such as rhinitis and asthma. To explore the cellular mechanisms behind eosinophil granule release in human allergic airways, 16 symptom-free patients with seasonal allergic rhinitis were challenged daily with allergen during 1 wk. Nasal lavage samples and biopsies, obtained before and 24
An initial-boundary value problem to a system of nonlinear partial differential equations, which consists of a hyperbolic and a parabolic part, is taken into consideration. The problem is discretised by a compact finite difference method. An approximation of the numerical solution is constructed, at which the difference scheme is linearised. Nonlinear convergence is proved using the stability of t
Cooking over open fire with solid fuels results in incomplete combustion and indoor air pollution (IAP) causing respiratory and other diseases leading to nearly two million premature deaths per year. In urban areas, IAP interacts with outdoor pollutants in toxic chemical mixtures affecting also other citizens and damaging regional air quality in terms of 'brown clouds'. Deaths result mainly in wom
This article shows how participation on national, regional and local levels is regulated in the infrastructure of the third generation of mobile telephony, 3G, in Sweden. This regulated participation, the “law in books”, is compared to participation in practice, the “law in action” perspective in the sense of the outcome and functionality of these regulations. This includes the identification of i
Abnormal vascularization of solid tumours results in the development of microenvironments deprived of oxygen and nutrients that harbour slowly growing and metabolically stressed cells. Such cells display enhanced resistance to standard chemotherapeutic agents and repopulate tumours after therapy. Here we identify the small molecule VLX600 as a drug that is preferentially active against quiescent c
Background: Substance use in general has been shown to predict criminal recidivism. The present study aimed to examine potential predictors of criminal recidivism, including substance-specific substance use patterns, in prisoners with substance use. Methods: A cohort of prisoners with substance use problems (N = 4,152) were assessed with the Addiction Severity Index (ASI) in the Swedish criminal j
In this paper is described the preparation of patterned cell dishes to be used in studies of low dose irradiation effects on living cells. Using a droplet microdispenser, an 8 mu m thick polypropylene cell substrate, to which cells do not naturally adhere, was coated in a matrix pattern with the cell adhesive mussel protein Cell-Tak. Cells were shown to adhere and grow on the protein-coated spots,
We report on a gated tunnel diode (GTD) and its operation in a 60 GHz pulsed oscillator, also known as a wavelet generator. The wavelet generator operates with the aid of a reactive bias stabilizing network, which minimizes the DC power consumption. This allows for 60 GHz wavelets as short as 56 ps to be produced, with a corresponding energy consumption of 1.0 pJ, which is a factor of 3.6 lower as
Sortilin, a member of the Vps10p-domain receptor family, has been demonstrated a key regulator in mediating cellular response to pro-neurotrophins. In the present study, we investigated the role of sortilin in the apoptotic pathway of vascular smooth muscle cells.
The main aim of this project was to explore whether the pine trees in Glen Affric (GAF), one of the more extensive pine woodlands in the northern Scottish Highlands, are, on average, reaching a senescent stage which could ultimately be detrimental to the sustainability of the pine woodland in this region under present management conditions This aim was realized by (1) comparing the mean stand age
Human aquaporin 2 (AQP2) is a water channel found in the kidney collecting duct, where it plays a key role in concentrating urine. Water reabsorption is regulated by AQP2 trafficking between intracellular storage vesicles and the apical membrane. This process is tightly controlled by the pituitary hormone arginine vasopressin and defective trafficking results in nephrogenic diabetes insipidus (NDI
Conducting social-ecological system (SES) research in fisheries aimed at aiding the implementation of a management plan that achieves sustainable outcomes remains a significant challenge. Using the Ostrom (2009) [1] diagnostic SES framework is widely utilized and acknowledged as an integral tool for research on SESs. The purpose of this article is to highlight and illustrate a comprehensive and ho
Scholarly discourses on energy security have developed in response to initially separate policy agendas such as supply of fuels for armies and transportation, uninterrupted provision of electricity, and ensuring market and investment effectiveness. As a result three distinct perspectives on energy security have emerged: the `sovereignty' perspective with its roots in political science; the `robust
Introduction: Acquired AmpC enzymes, classified as miscellaneous extended-spectrum beta-lactamase (ESBLM) enzymes according to a recently proposed beta-lactamase classification, are increasing according to several publications. Simple and rapid methods for detection of ESBLM are needed for appropriate infection control. A gel-based multiplex PCR method for acquired bla(AmpC) detection and subtype
