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Autocatalytic amplification of Alzheimer-associated Aβ42 peptide aggregation in human cerebrospinal fluid

Alzheimer’s disease is linked to amyloid β (Aβ) peptide aggregation in the brain, and a detailed understanding of the molecular mechanism of Aβ aggregation may lead to improved diagnostics and therapeutics. While previous studies have been performed in pure buffer, we approach the mechanism in vivo using cerebrospinal fluid (CSF). We investigated the aggregation mechanism of Aβ42 in human CSF thro

An Economic Model for Estimating Trial Costs with an Application to Placebo Surgery Trials

Background and Objective: Waste in clinical trials remains rife. We developed an economic model to predict the cost of trials based on input costs, duration, power, number of sites, recruitment eligibility and consenting rates. Methods: We parameterised the model for three proxy placebo-controlled surgical trials using data from a systematic review, a bespoke cost survey, and from the literature.

Effect of magnetic order on longitudinal Tomonaga-Luttinger liquid spin dynamics in weakly coupled spin-1/2 chains

The quantum many-body interactions in one-dimensional spin- 1/2 systems are subject to Tomonaga-Luttinger liquid (TLL) physics, which predict an array of multiparticle excitations that form continua in momentum-energy space. Here we use inelastic neutron spectroscopy to study the TLL spin dynamics in SrCo2V2O8 , a compound which contains weakly coupled spin-1/2 chains of Co atoms, at 0.05 K and in

Acceptorless dehydrogenation of 4-methylpiperidine by supported pincer-ligated iridium catalysts in continuous flow

Finding alternative and sustainable ways to produce, store and convert energy is key for reducing fossil fuel-based CO2 emissions. In this transformation, hydrogen for energy storage and hydrogen-powered fuel cells for energy conversion can play important roles. However, storage of hydrogen itself is difficult and the concept of reversible liquid organic hydrogen carriers (LOHCs) has been proposed

Sex and gender in infection and immunity : addressing the bottlenecks from basic science to public health and clinical applications

Although sex and gender are recognized as major determinants of health and immunity, their role is rarely considered in clinical practice and public health. We identified six bottlenecks preventing the inclusion of sex and gender considerations from basic science to clinical practice, precision medicine and public health policies. (i) A terminology-related bottleneck, linked to the definitions of

Chemical Limits on X-ray Nanobeam Studies in Water

Operando X-ray studies of chemical reactions have gained increasing interest lately, fueled by the emergence of a new generation of powerful focused X-ray sources. Although it is well known that ionizing radiation causes damage to samples via radical chemistry, this effect is often overlooked in studies of working devices or catalysts where intense focused beams are used as nanoscale probes. Here,

ANTAGNINGSORDNING Beslut US 2024-06-18

Lägg till titel Sida 1 av 28 Universitetsstyrelsen BESLUT Diarienummer I G 9 6251/2004 LS 2012/719) STYR 2017/409 STYR 2024/288 Datum 2024-06-18 Innehåll Antagningsordning för utbildning på forskarnivå vid Lunds universitet 1. Inledning .................................................................................. 3 2. Information om ledig utbildningsplats samt om ledig anställning som doktora

https://www.intramed.lu.se/sites/intramed.lu.se/files/2024-07/ANTAGNINGSORDNING%20beslut%20US%202024-06-18.pdf - 2026-05-23

Hao fuchun

Microsoft Word - Hao_Fuchun_Revised.doc LUMES Master Thesis 2003 1 The Three Gorges Project: A Dilemma of Energy Security and Sustainable Development in China Hao Fuchun Scientific supervisor: Per Svenningsson LUMES Master Thesis 2003 2 Acknowledgements: First of all I would like to express my deep gratitude to people whose invaluable help and support made this paper possible, especially my ever-p

https://www.lumes.lu.se/sites/lumes.lu.se/files/hao_fuchun.pdf - 2026-05-23

Emily sonestedt cv hemsidan ludc 161031

Sonestedt, PhD CV November 2016 Curriculum Vitae Emily Sonestedt Address: Clinical Research Centre, 60:13, Jan Waldenströms gata 35, SE-205 02 Malmö, Sweden E-mail: emily.sonestedt@med.lu.se Telephone: +46(0)40 39 13 25 Mobile: +46(0)737 00 71 45 ORCID ID: 0000-0002-0747-4562 EDUCATION 2009 PhD, public health. Title: Plant foods, plasma enterolactone and breast cancer – with a focus on estrogen re

https://www.ludc.lu.se/sites/ludc.lu.se/files/emily_sonestedt_cv_hemsidan_ludc_161031.pdf - 2026-05-23

Ramos isabel

Introduction Lund University International Master’s Programme in Environmental Science Master Thesis How can Transfrontier Conservation Areas (TFCAs) Promote Sustainable Development? Isabel Maria Matos Dias Ramos isabelramos@yahoo.com Rua António Patrício 107 – 1º 4150 – 100 Porto / Portugal Phone : (++) 351 96 670 18 07 Thesis Advisor Åsa Mattsson asa.mattsson@svet.lu.se Political Science Departm

https://www.lumes.lu.se/sites/lumes.lu.se/files/ramos_isabel.pdf - 2026-05-23

Cfewp06

CFE-Paper A5 ver 7 1Research and Development Cooperation in European Competition Law Research and Development Cooperation in European Competition Law - A Legal and Economic Analysis Marcus Glader Marcus.Glader@jur.lu.se Marcus Glader is a Ph D Candidate at the Faculty of Law, Lund University, Sweden. This working paper is based on his Master Thesis entitled Horizontal Restraints – Research and Dev

https://www.cfe.lu.se/en/sites/cfe.lu.se.en/files/2020-12/cfewp06.pdf - 2026-05-23

Popularvetenskaplig.rapport v4

Psykologiska rapporter från Lund Volym 6, Nr. 1, 2013 Åsikter och engagemang i samhällsfrågor Resultat från en webbundersökning Emma A. Bäck, Hanna Bäck, Henry Montgomery och Felix Funck Institutionen för psykologi, Lunds universitet Psykologiska rapporter från Lund Redaktör: Magnus Lindgren ISSN 1404-8124 Åsikter och engagemang i samhällsfrågor – Bäck, Bäck, Montgomery & Funck 2 Åsikter och engag

https://www.psy.lu.se/sites/psy.lu.se/files/popularvetenskaplig.rapport_v4.pdf - 2026-05-23

Vol8no3

Microsoft Word - Discriminating.doc Lund Psychological Reports Volume 8, No. 3 2007 Discriminating Depressive Patients and Patients with Somatoform Disorders by Means of the Beck Depression Inventory (BDI) Lars Olsson Department of Psychology Lund Psychological Reports Editors: Magnus Lindgren & Sven Birger Hansson ISSN 1404-8035 Discriminating Depressive Patients and Patients with Somatoform Diso

https://www.psy.lu.se/sites/psy.lu.se/files/vol8no3.pdf - 2026-05-23

Behov och applicering av riskbaserad brandskyddsdimensionering i Sverige

I Sverige såväl som övriga världen ökar befolkningen för varje dag som går. Våra städer förtätas och överallt dyker nya byggnader upp. Förutom att uppföra fler byggnader vill vi även att dessa ska vara höga och på andra sätt komplexa. Detta ställer i sin tur högre krav på projektören som ska säkerställa byggnadens brandskydd. För att bestämma hur brandskyddet ska utformas i byggnader kan projektöAs buildings get more and more complex and our cities get more and more populated, challenges arise for the persons involved in designing buildings. One of the most important system, the fire protection measures, needs to be designed properly for every building. As the buildings get more complex, the fire protection design needs more often to be flexible and appropriate for the situation. One way

Who cares for urban repair? Stretching the life of buildings, the case of the Edman Pavillion in Lund’s (Sweden) People’s Park.

In architecture and urban geography, discussions on repair, maintenance and adap5ve re-usehave emerged as a crucial intellectual terrain. Temporal aspects of how the urban fabric isused have also emerged as an issue worth theore5cal and empirical a=en5on. Latching ontothese themes, we will present work tracking the history of conten5on around the publiclyowned mee5ng and arts venue in Lund’s Peopl

Immunotherapy for Atherosclerosis

Cardiovascular disease is the global number one causeof mortality and morbidity. The majority of cardio vascular diseases are caused by atherosclerosis, a lipid-driven, inflammatory disease of the middle- and large-sized arteries. The disease is characterized by the formation of atherosclerotic plaques throughout the arterial tree. Over the years, insights intohe pathogenesis of atherosclerosis ha

The Association between Dietary Energy Density and Type 2 Diabetes in Europe: Results from the EPIC-InterAct Study

Background: Observational studies implicate higher dietary energy density (DED) as a potential risk factor for weight gain and obesity. It has been hypothesized that DED may also be associated with risk of type 2 diabetes (T2D), but limited evidence exists. Therefore, we investigated the association between DED and risk of T2D in a large prospective study with heterogeneity of dietary intake. Meth

The Tetraspanin CD9 Affords High-Purity Capture of All Murine Hematopoietic Stem Cells

Prospective isolation is critical for understanding the cellular and molecular aspects of stem cell heterogeneity. Here, we identify the cell surface antigen CD9 as a positive marker that provides a simple alternative for hematopoietic stem cell isolation at high purity. Crucially, CD9 affords the capture of all hematopoietic stem cells in murine bone marrow in the absence of contaminating populat