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Context-Dependent Effects of Amino Acid Supplementation on Nestling Growth and Baseline Innate Immune Function

Growth and immune development—fundamental parts of any organism's ontogeny—depend critically on nutrient availability, particularly on essential amino acids that support protein synthesis and physiological processes. However, environmental variation can reduce prey diversity and nutrient quality, producing suboptimal diets that lack essential amino acids, potentially constraining development. In t

Longitudinal screening of HLA-risk and HLA-nonrisk children for celiac disease to age 15 years: CiPiS study

ObjectivesAutoantibodies against tissue transglutaminase (tTG) are serological markers of celiac disease. The aim was to study the applicability of human leukocyte antigen (HLA)-genotyping and tTG autoantibodies in the screening of celiac disease in a longitudinal birth cohort followed to age 15 years.MethodsIncluded were 13,860 HLA-DQ-genotyped children at birth and previously invited to a screen

Associations between residential greenness, land cover and risk of celiac disease in genetically at-risk children: Celiac Prediction in Skåne study

ObjectivesOur aim was to study the association between residential land cover and greenness during childhood and risk of developing celiac disease (CeD).MethodsThe Celiac Prediction in Skåne study prospectively followed 5969 human leukocyte antigen (HLA)-genotyped children born 2001–2004 who were screened for CeD at ages 3, 9, and 15 years in Skåne, Sweden. Among these, 138 (2.3%) children only in

Ex vivo and in vivo immunomodulation in acute lung injury and lung transplantation

Lung transplantation (LTx) remains the only curative treatment for patients with end-stage lung disease, yet long-term outcomes remain inferior to those of other solid organ transplantations, with a 5-year survival below 70%. Major contributors to this limited outcome include primary graft dysfunction (PGD), the leading cause of early mortality, chronic lung allograft dysfunction (CLAD), and low u

Porous media characterization for fuel cell optimization : a mesoscopic approach via Lattice Boltzmann Method

The efficiency and durability of Polymer Electrolyte Fuel Cells (PEFCs) depend on optimizing porous media components such as gas diffusion and catalyst layers. In parallel, the Lattice Boltzmann Method (LBM) has emerged as a powerful tool to model fluid flow, mass transport, and multiphase interactions in complex porous structures. This works provides a concise overview of recent advances in apply

Sjalvstandiga arbeten vid lu

1 QuousQue tandem abutere UTVÄRDERING, RAPPORT 2015:275 Att genomföra ett självständigt arbete vid Lunds universitet -studenters perspektiv ola holmström | lunds universitet Kvalitet och Utvärdering Lunds universitet Box 117 221 00 Lund Tel. vx: 046-222 00 00 Tel: 046-222 70 45 Fax: 046-222 40 07 ISBN 978-91-7623-521-8 (Serien Utvärdering Rapporter är en fortsättning av serien Utvärderingsenheten

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/sjalvstandiga_arbeten_vid_lu.pdf - 2026-05-23

Risk of hospitalization for type 2 diabetes in first- and second-generation immigrants in Sweden: a nationwide follow-up study.

OBJECTIVES: This is the first nationwide study with the aim to analyze whether there is an association between country of birth in first-generation immigrants and hospitalization for type 2 diabetes (T2D), and to study whether any such association remains in second-generation immigrants. DESIGN: In this follow-up study, the Swedish Hospital Discharge Register was used to identify all hospital

Design of a high-density multi-channel electrode for multi-structure parallel recordings in rodents

In neurophysiology, investigating brain connectivity within and between different brain structures is of fundamental importance for understanding nervous system function and its relation to behavior. Yet, parallel recordings in multiple brain structures is highly challenging, especially in rodents, which are most commonly employed in neurophysiological research but rather small in size. In this st

A comparison of complementary measures of vitamin B6 status, function, and metabolism in the European Prospective Investigation into Cancer and Nutrition (EPIC) study

Background: Vitamin B6 insufficiency has been linked to increased risk of cancer and other chronic diseases. The circulating concentration of pyridoxal 5-phosphate (PLP) is a commonly used measure of vitamin B6 status. Ratios of substrates indicating PLP coenzymatic function and metabolism may be useful complementary measures to further explore the role of vitamin B6 in health. Objectives: We expl

Correlation between physical activity, aerobic fitness and body fat against autonomic function profile in children

AIM: To evaluate correlations between physical activity, VO2PEAK and body fat versus autonomic function in children.METHODS: Children (n = 98) between 10 and 12 years underwent a maximal exercise test (VO2PEAK) and dual-energy X-ray absorptiometry measured body fat. General physical activity, moderate to vigorous physical activity and vigorous physical activity were assessed by accelerometers. Dee

Quantification of the Concentration of A beta 42 Propagons during the Lag Phase by an Amyloid Chain Reaction Assay

The aggregation of the amyloid beta peptide, A beta 42, implicated in Alzheimer's disease, is characterized by a lag phase followed by a rapid growth phase. Conventional methods to study this reaction are not sensitive to events taking place early in the lag phase promoting the assumption that only monomeric or oligomeric species are present at early stages and that the lag time is defined by the

High Familial Risk of Atrial Fibrillation/Atrial Flutter in Multiplex Families: A Nationwide Family Study in Sweden

Background-Although the heritability of atrial fibrillation/atrial flutter (AF/AFl) has been determined, the familial risk in multiplex families is unclear. The main aim of this nationwide study was to determine the familial risk of AF/AFl in multiplex families. Methods and Results-We examined the familial risk of AF/AFl in the entire Swedish population. We linked Multigeneration Register data on

High-Performance InAs Nanowire MOSFETs

In this letter, we present a 15-nm-diameter InAs nanowire MOSFET with excellent on and off characteristics. An n-i-n doping profile was used to reduce the source and drain resistances, and an Al2O3/HfO2 bilayer was introduced in the high-k process. The nanowires exhibit high drive currents, up to 1.25 A/mm, normalized to the nanowire circumference, and current densities up to 34 MA/cm2 (VD = 0.5 V

Evaluation of hand bone loss by digital X-ray radiogrammetry as a complement to clinical and radiographic assessment in early rheumatoid arthritis: results from the SWEFOT trial

Background: To investigate hand bone loss (HBL) measured by digital X-ray radiogrammetry (DXR) in patients with early rheumatoid arthritis (RA) receiving different treatment regimens, and to evaluate if DXR change rates during the first 12 months correlate with radiological damage after 24 months. Methods: From the total SWEFOT trial population, 159 patients had hand radiographs correctly timed an

Perinatal and Family Risk Factors for Non-Hodgkin Lymphoma in Early Life: A Swedish National Cohort Study.

Background: The incidence of non-Hodgkin lymphoma (NHL) in early life has increased in recent decades, but the relevant risk factors remain largely unknown. We examined perinatal and family risk factors for NHL in childhood through young adulthood. Methods: We conducted a national cohort study of 3 571 574 individuals born in Sweden in 1973-2008 who were followed for incidence of NHL through 2009

Age- and gender-specific familial risks for venous thromboembolism: a nationwide epidemiological study based on hospitalizations in sweden.

Background- This nationwide study sought to determine age- and gender-specific familial risks in siblings hospitalized for venous thromboembolism (VTE). Methods and Results- The Swedish Multigeneration Register on 0- to 75-year-old subjects was linked to the Hospital Discharge Register for the years 1987-2007. Standardized incidence ratios were calculated for individuals whose siblings were hospit