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Background and Objective: Universities can be understood as work-like environments for students. Limited research has examined this study environment from a Demand-Control-Support perspective with regards to sexual harassment. Understanding this environment is key to designing preventative measures. This study therefore aimed to examine the association between individual and psychosocial study env

Genetic variants affectingHeterogeneousNuclear RibonucleoproteinU (HNRNPU) have been identified in several neurodevelopmental disorders (NDDs). HNRNPU is widely expressed in the human brain and shows the highest postnatal expression in the cerebellum. Recent studies have investigated the role of HNRNPU in cerebral cortical development, but the effects of HNRNPU deficiency on cerebellar development

Background: The period after a child is discharged from hospital is generally described as challenging for the parents. Their satisfaction with the health services received is an important indicator of the quality of care. eHealth devices are increasingly used in health care to support communication with parents. Differences in levels of parental satisfaction by modality of provided care or by par

The backbone of modern computing systems rely on two key things: logic and memory, and while computing power hasseen tremendous advancements through scaling of the fundamental building block – the transistor, memory access hasn’tevolved as rapidly, leading to significant memory-bound systems. Additionally, the rapid evolution of machine learningand deep neural network (DNN) applications, has expos

Mathematical models of cancer and bacterial evolution have generally stemmed from a gene-centric framework, assuming clonal evolution via acquisition of resistance-conferring mutations and selection of their corresponding subpopulations. More recently, the role of phenotypic plasticity has been recognized and models accounting for phenotypic switching between discrete cell states (e.g., epithelial

Rubella virus encodes a nonstructural polyprotein with RNA polymerase, methyltransferase, and papain-like cysteine protease activities, along with a putative macrodomain of unknown function. Macrodomains bind ADP-ribose adducts, a post-translational modification that plays a key role in host-virus conflicts. Some macrodomains can also remove the mono-ADP-ribose adduct or degrade poly-ADP-ribose ch

Neural induction by cell-cell signaling was discovered a century ago by the organizer transplantations of Spemann and Mangold in amphibians. Spemann later found that early dorsal blastopore lips induced heads and late organizers trunk-tail structures. Identifying region-specific organizer signals has been a driving force in the progress of animal biology. Head induction in the absence of trunk is

Feathers comprise a series of evolutionary innovations but also harbour colour, a key biological trait known to co-vary with life history or complex traits. Those relationships are particularly true in melanin-based pigmentation species due to known pleiotropic effects of the melanocortin pathway – originating from melanin-associated phenotypes. Here, we explore the molecular basis of melanin colo

We conducted a multi-ancestry genome-wide association study of prostate-specific antigen (PSA) levels in 296,754 men (211,342 European ancestry; 58,236 African ancestry; 23,546 Hispanic/Latino; 3,630 Asian ancestry; 96.5% of participants were from the Million Veteran Program). We identified 318 independent genome-wide significant (p≤5e-8) variants, 184 of which were novel. Most demonstrated eviden

Citizen Science (CS) projects targeting senior citizens and persons with functional impairments are rare, and interest among citizens to become involved in such remains uncertain. There is a lack of systematic analyses as to what distinguishes citizens’ willingness to contribute, and what such involvement could lead to in terms of acquired skills or changed attitudes. Based on a Swedish CS project

Background: Home mechanical ventilation (HMV), noninvasive ventilation and invasive ventilation outside a hospital setting, is a key treatment to improve outcomes in chronic hypoventilation. Research Question: What are the temporal trends observed over 27 years in Sweden regarding the incidence, prevalence, diagnostic spectrum, and patient characteristics associated with HMV? Study Design and Meth

Aims: The left atrial appendage (LAA) produces natriuretic peptides and its removal or occlusion might increase the risk of heart failure (HF). We aimed to investigate the incidence of HF after LAA occlusion or removal (LAAO) in the Left Atrial Appendage Occlusion Study (LAAOS III). Methods and results: Patients (n = 4811) with atrial fibrillation (AF) and a CHA2DS2-VASc score ≥2, who were having

We conducted a multiancestry genome-wide association study of prostate-specific antigen (PSA) levels in 296,754 men (211,342 European ancestry, 58,236 African ancestry, 23,546 Hispanic/Latino and 3,630 Asian ancestry; 96.5% of participants were from the Million Veteran Program). We identified 318 independent genome-wide significant (P ≤ 5 × 10 -8) variants, 184 of which were novel. Most demonstrat

BACKGROUND: Sustained intrauterine hypoxia causes some four million perinatal deaths annually worldwide. The condition is predicated by neonatal acidemia, as determined by pH in umbilical cord blood at birth. We aimed to evaluate the association between umbilical cord arterial pH and long-term outcomes up to 20 years of follow-up.STUDY DESIGN: Using a retrospective cohort design, umbilical cord ar

Aim: Public health nurses working in high schools have few set tasks, and there is limited research available on their flexible role. Therefore, the aim of the study was to describe public health nurses’ perspectives on their role when working in Norwegian high schools. Design: A qualitative descriptive design, with an inductive approach. Sample: Eight public health nurses with at least 1-year of

Lahti, A, Grundberg, A, Stenman, E, and Sundquist, K. Physical characteristics of Swedish female professional ice hockey players allowed body checking. J Strength Cond Res XX(X): 000-000, 2024 - In ice hockey, physical characteristics impact sporting performance. This study aims to describe body height, body mass, and body mass index (BMI) in professional female ice hockey players in the Swedish W