Filtyp
The aim of this study was to demonstrate proof-of-concept feasibility for the use of human neural stem cells (NSCs) for high-throughput screening (HTS) applications. For this study, an adherent human induced pluripotent stem (iPS) cell-derived long-term, self-renewing, neuroepithelial-like stem (lt-NES) cell line was selected as a representative NSC. Here, we describe the automated large-scale ser
CONTEXT: The epidemiological focus on time loss may underestimate the true magnitude of hip and groin problems in male ice hockey players.OBJECTIVE: To describe the prevalence, incidence and severity of hip and groin problems (time loss and non-time-loss) in Swedish ice hockey players over the course of a season and to explore potential pre-season risk factors for these problems.DESIGN: Prospectiv
Over the last decades, rapid technological and scientific advances have led to a merge of molecular sciences and clinical medicine, resulting in a better understanding of disease mechanisms and the development of novel therapies that exploit specific molecular lesions or profiles driving disease. Precision oncology is here used as an example, illustrating the potential of precision/personalized me
Objective In 2015, new FIGO guidelines for CTG interpretation were presented (FIGO-15). In 2017, the previous Swedish guidelines (SWE-09) were replaced with guidelines adapted to FIGOs (SWE-17). The performance of these three templates had not been scientifically evaluated before its clinical implementation. The objective of this study was to compare the sensitivity and specificity to detect fetal
Background. In Sweden, both glucose analyzers in accredited laboratories and point-of-care glucose devices are used for gestational diabetes mellitus (GDM) diagnosis. The aim of this study was to compare the diagnostic performance of the HemoCue Glucose 201+ (HC201+) and RT (HC201RT) systems with that of the hospital central laboratory hexokinase method (CL) based on lyophilized citrate tubes, usi
Purpose: To investigate access to basic human rights such as health, a standard of living adequate for health, education, work, marrying and establishing a family, and voting for prosthetic and orthotic users with lower limb disabilities in Malawi. Materials and methods: A cross-sectional design and a questionnaire were used to collect data from 83 participants. Results: Most participants reported
It is normally assumed that induced transitions, by e.g. hyperfine, magnetic field or spin interaction, arise due to mixing in the upper levels. In this paper we discuss an example when mixing in the lower levels through an externally applied magnetic field gives rise to a magnetic field induced transition. We discuss the theory for such a transition and give an example from Fe X, which is relevan
Different than the traditional body of work of this field that claims water scarcity leads to conflict, or to another line of research that claims water scarcity actually leads to cooperation; this article proposes a different causal mechanism that links the importance of the pattern of relations existing between countries prior to climate change and resource scarcity, to try to explain why water
Background Rectal bleeding is considered an alarm symptom for colorectal cancer (CRC) but it is common and mostly caused by benign conditions. Qualitative faecal immunochemical tests (FITs) for occult blood have been used as diagnostic aids for many years in Sweden when CRC is suspected. The study aimed to evaluate the usefulness of FITs requested by primary care physicians for patients with and w
Background and purpose: Biochemical recurrence after prostatectomy is commonly treated with salvage radiotherapy (SRT). In this prospective observational study we investigated the PSA decay rate, determined by predefined serial PSA measurements during SRT, as a predictor for treatment outcome.Materials and methods: Between 2013 and 2016, 214 patients were included in the study. The prescribed dose
HCV infection is a major risk factor for liver cancer and liver transplantation worldwide. Overstimulation of host lipid metabolism in the liver by HCV-encoded proteins during viral infection creates a favorable environment for virus propagation and pathogenesis. In this study, we hypothesize that targeting cellular enzymes acting as master regulators of lipid homeostasis could represent a powerfu
Introduction: It remains unclear whether offering psychiatric patients their preferred treatment influences outcomes at the symptom level. Objective: To assess whether offering patients with Panic Disorder with/without Agoraphobia (PD/A) a choice between two psychotherapies yields superior outcomes to random assignment. Methods: In a doubly randomised, controlled preference trial (DRCPT), 221 adul
Syftet med uppsatsen är att generera kunskap om skillnader mellan svensk och dansk förhandlingsstil. Det teoretiska syftet är att testa ifall det går att mäta skillnader i förhandlingsstil inom kulturella kluster. Med en kvantitativ forskningsansats har vi undersökt skillnader mellan svensk och dansk förhandlingsstil. För datainsamling använde vi en elektronisk enkät som vi skickade till 305 chefe
Purpose: The purpose of the thesis is to critically review different pricing strategies with a special focus on Revenue Management and discuss the possibilities and challenges for hotels when optimising their profitability. Methodology: We have conducted three case studies on hotels located in the Öresund region. The studies were done with a qualitative research approach. The respondents are all w
Skolan är en institution som påverkas av samhället och i bästa fall påverkar samhället. I teoridelen beskrivs skolan som en institution som samvarierar med samhället. I takt med kraven på decentralisering och platta organisationer har skolans lokala arbetsplan blivit ett uttryck för den lokala handlingsfriheten i skolans värld. Detta medför att skolornas arbetsplaner ser olika ut innehållsmässigt.
I svensk rätt finns tre typer av kriminaliserade förstadier till brott&semic försök, förberedelse och stämpling. Försöksbrottet ligger tidsmässigt närmast det fullbordade brottet. Ansvar för försök förutsätter att gärningsmannen kan sägas ha påbörjat utförandet av brottet, d v s att han passerat den s k försökspunkten. Har försökspunkten ännu inte passerats kan ansvar för förberedelse eller st
Cities are becoming smart to cope with the challenges associated with urban development. One of the cities trying to become smart is the City of Stockholm, which in 2017 adopted a strategy to become the world’s smartest and most connected city. However, becoming a smart city is not easy. The transformation requires a new organizational approach and innovation in management, which the City of Stock
As legislators in recent years have adopted regulations demanding companies to disclose information on their supply chains, a new chapter of corporate transparency has been opened. However, what power such regulations have to initiate a change of corporate behaviour is questionable. In this thesis the most topical of the recently adopted supply chain transparency and due diligence regulations, are
