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While research on the design of heterogeneous concurrent systems has a long and rich history, a unified design methodology and tool support has not emerged so far, and thus the creation of such systems remains a difficult, time-consuming and error-prone process. The absence of principled support for system evaluation and optimization at high abstraction levels makes the quality of the resulting im
BACKGROUND: Androgen insensitivity is caused by mutations in the androgen receptor gene, and is a common etiological factor to ambiguous genitalia in the newborn. This article discusses the role of androgens in sex differentiation, the structure and function of the androgen receptor, the genetic background to androgen insensitivity as well as clinical aspects. MATERIAL AND METHODS: The article is
Attneave's (1968) pointing triangle illusion consists of a display of ipsilateral triangles. Perceiving the display results in the illusion that the triangles point in a certain direction. Spontaneous switches in pointing direction are observed. Blink frequency significantly decreases before the switches witnessing for a nonspecific preparation process to perceptual and motor response events. Sacc
‘Flight shame’ describes an unease about the climate implications of air travel, and bears evidence of a change in social norms that have so far associated flying with social status. This paper discusses whether Fridays for Future demonstrations and ensuing flight shame have influenced social norms regarding the desirability of air travel, and whether this is measurable in a decline in air travel,
1. Dementia is a clinical syndrome with several causes whichcreates impairments in mental ability, personality, affect andsocialisation.2. Information from family members can be very useful in theearly identification of cognitive impairment.3. Patients presenting with cognitive impairment should be evaluatedfor potentially reversible causes, with a range of laboratorytests and investigations.4. Sh
The members of the genus Caldicellulosiruptor have the potential for future integration into a biorefinery system due to their capacity to generate hydrogen close to the theoretical limit of 4 mol H2/mol hexose, use a wide range of sugars and can grow on numerous lignocellulose hydrolysates. However, members of this genus are unable to survive in high sugar concentrations, limiting their ability t
This chapter concerns disabled people’s experiences of barriers to accessing sexuality. It draws on an analysis of materials produced in ten projects by civil society organisations, including self-advocacy organisations, sexual rights organisations and organisations working on behalf of disabled people. These materials comprise books, handbooks, videos, websites and other online materials, and are
Aim of the studyRates of bystander CPR are increasing, yet mortality after out-of-hospital cardiac arrest (OHCA) remains high. The aim of this survey was to explore public knowledge and attitudes to CPR. Our hypotheses were that recent CPR training (< 5 years) would be associated with a high-quality response in a case vignette of OHCA with agonal breathing, and associated with an interest to becom
Droplet microfluidics is a powerful method to characterize chemical reactions at high throughput. Often detection is performed via in-line optical readout, which puts high demands on the detection system and makes detection of low concentration substrates challenging. Here, we have developed a droplet acoustofluidic chip for time-controlled microbead-based reactions that is combined with off-line
We present a microfluidic system to control the position of particles (polystyrene beads or astrocyte cells) in hydrogel droplets using bulk acoustic standing waves. Droplets comprising hydrogel precursor solution, photoinitiator and (bio-)particles were generated and acoustic forces focused the beads to the droplet center line. Droplets were cross-linked by exposure to UV-light. With the acoustic
Quinoa (Chenopodium quinoa Willd.) has gained recent popularity mainly due to its attractive nutritional profile and its ability to grow under extreme conditions such as salinity, acidity, drought, flooding, and frost as well as the functionality of its component. Starch is the main component of quinoa grain which constitutes up to 60% of the dry grain and plays a crucial role in the functional pr
Purpose of review: In comatose cardiac arrest survivors, the electroencephalogram (EEG) is the most widely used test to assess the severity of hypoxic-ischemic brain injury (HIBI) and guide antiseizure treatment. However, a wide variety of EEG patterns are described in literature. Moreover, the value of postarrest seizure treatment is uncertain. Absent N20 waves of short-latency somatosensory-evok
Baserat på fullständiga sammanställningar av subskriptionerne på 2 Timoteusbrevet i 485 grekiska manuskript, presenterar denna studie texttraditionen och utvecklingen av dessa subskriptioner och förklarar deras förhållande till andra subskriptioner, paratexter, de interna material i 1–2 Timoteus, Apostlagärningarna och det bredare. kyrkohistoria. Studien spårar källan/källorna bakom traditionen atBased on full collations of the subscriptions to 2 Timothy in 485 Greek manuscripts, this study presents the textual tradition and development of these subscriptions and explains their relationship to other subscriptions, paratexts, the internal evidence in 1–2 Timothy, Acts, and the wider church history. The study tracks the source(s) behind the tradition that the letter was sent to Timothy, inst
DNA carries the genetic code of life, with different conformations associated with different biological functions. Predicting the conformation of DNA from its primary sequence, although desirable, is a challenging problem owing to the polymorphic nature of DNA. We have deployed a host of machine learning algorithms, including the popular state-of-the-art LightGBM (a gradient boosting model), for b
